ROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells
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Title
ROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells
Authors
Keywords
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Journal
Scientific Reports
Volume 8, Issue 1, Pages -
Publisher
Springer Nature America, Inc
Online
2018-11-05
DOI
10.1038/s41598-018-35109-9
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- (2013) Xindong Liu et al. IMMUNOLOGICAL REVIEWS
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- (2012) C. S. Ma et al. BLOOD
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