Repeated rectal application of a hyperosmolar lubricant is associated with microbiota shifts but does not affect PrEP drug concentrations: results from a randomized trial in men who have sex with men

Short Communication: Anatomic Site of Sampling and the Rectal Mucosal Microbiota in HIV Negative Men Who Have Sex with Men Engaging in Condomless Receptive Anal Intercourse

(2018) Nicole A. Pescatore et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Inflammation and pharmacokinetics: potential implications for HIV-infection

(2017) Sharon M. Seifert et al.   Expert Opinion on Drug Metabolism & Toxicology

The immune response to Prevotella bacteria in chronic inflammatory disease

(2017) Jeppe Madura Larsen   IMMUNOLOGY

Levels of Intracellular Phosphorylated Tenofovir and Emtricitabine Correlate With Natural Substrate Concentrations in Peripheral Blood Mononuclear Cells of Persons Prescribed Daily Oral Truvada for HIV Pre-exposure Prophylaxis

(2017) Richard E. Haaland et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women

(2017) Nichole R. Klatt et al.   SCIENCE

Efficacy of oral pre-exposure prophylaxis (PrEP) for HIV among women with abnormal vaginal microbiota: a post-hoc analysis of the randomised, placebo-controlled Partners PrEP Study

(2017) Renee Heffron et al.   Lancet HIV

Intracellular Tenofovir and Emtricitabine Anabolites in Genital, Rectal, and Blood Compartments from First Dose to Steady State

(2016) Sharon M. Seifert et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Intestinal microbiome disruption in patients in a long-term acute care hospital: A case for development of microbiome disruption indices to improve infection prevention

(2016) Alison Laufer Halpin et al.   AMERICAN JOURNAL OF INFECTION CONTROL

The rectal mucosa and condomless receptive anal intercourse in HIV-negative MSM: implications for HIV transmission and prevention

(2016) C F Kelley et al.   Mucosal Immunology

Prevotella in the gut: choose carefully

(2016) Ruth E. Ley   Nature Reviews Gastroenterology & Hepatology

Use of a Prospective Sex Diary to Study Anal Lubricant and Enema Use Among High Risk Men Who Have Sex With Men—Implications for Human Immunodeficiency Virus Prevention

(2016) Charlotte-Paige Melanie Rolle et al.   SEXUALLY TRANSMITTED DISEASES

Interpreting Prevotella and Bacteroides as biomarkers of diet and lifestyle

(2016) Anastassia Gorvitovskaia et al.   Microbiome

Gut Microbiota Linked to Sexual Preference and HIV Infection

(2016) Marc Noguera-Julian et al.   EBioMedicine

Pharmacokinetic profile of raltegravir, elvitegravir and dolutegravir in plasma and mucosal secretions in rhesus macaques

(2015) Ivana Massud et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection

(2015) Jean-Michel Molina et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mucosal effects of tenofovir 1% gel

(2015) Florian Hladik et al.   eLife

Rectal Application of a Highly Osmolar Personal Lubricant in a Macaque Model Induces Acute Cytotoxicity but Does Not Increase Risk of SHIV Infection

(2015) Sundaram A. Vishwanathan et al.   PLoS One

HIV Protective Efficacy and Correlates of Tenofovir Blood Concentrations in a Clinical Trial of PrEP for HIV Prevention

(2014) Deborah Donnell et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Senior Thai Fecal Microbiota Comparison Between Vegetarians and Non-Vegetarians Using PCR-DGGE and Real-Time PCR

(2014) Supatjaree Ruengsomwong et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia

(2014) S M Dillon et al.   Mucosal Immunology

Effect of Mobile Phase pH and Organic Content on LC--MS Analysis of Nucleoside and Nucleotide HIV Reverse Transcriptase Inhibitors

(2013) Z. Kuklenyik et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Is Wetter Better? An Evaluation of Over-the-Counter Personal Lubricants for Safety and Anti-HIV-1 Activity

(2012) Charlene S. Dezzutti et al.   PLoS One

Emtricitabine-Tenofovir Concentrations and Pre-Exposure Prophylaxis Efficacy in Men Who Have Sex with Men

(2012) P. L. Anderson et al.   Science Translational Medicine

Identification of Personal Lubricants That Can Cause Rectal Epithelial Cell Damage and Enhance HIV Type 1 Replication in Vitro

(2011) Othell Begay et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Generation of Multimillion-Sequence 16S rRNA Gene Libraries from Complex Microbial Communities by Assembling Paired-End Illumina Reads

(2011) Andrea K. Bartram et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Natural Substrate Concentrations Can Modulate the Prophylactic Efficacy of Nucleotide HIV Reverse Transcriptase Inhibitors

(2011) J. G. Garcia-Lerma et al.   JOURNAL OF VIROLOGY

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

The Slippery Slope: Lubricant Use and Rectal Sexually Transmitted Infections: A Newly Identified Risk

(2011) Pamina M. Gorbach et al.   SEXUALLY TRANSMITTED DISEASES

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men

(2010) Robert M. Grant et al.   NEW ENGLAND JOURNAL OF MEDICINE

PyNAST: a flexible tool for aligning sequences to a template alignment

(2009) J. G. Caporaso et al.   BIOINFORMATICS

On-line coupling of anion exchange and ion-pair chromatography for measurement of intracellular triphosphate metabolites of reverse transcriptase inhibitors

(2009) Zsuzsanna Kuklenyik et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

FastTree: Computing Large Minimum Evolution Trees with Profiles instead of a Distance Matrix

(2009) M. N. Price et al.   MOLECULAR BIOLOGY AND EVOLUTION

Mucosal Irritation Potential of Personal Lubricants Relates to Product Osmolality as Detected by the Slug Mucosal Irritation Assay

(2008) Els Adriaens et al.   SEXUALLY TRANSMITTED DISEASES