Article
Medicine, General & Internal
Gerard P. Slobogean, Sheila Sprague, Jeffrey L. Wells, Lehana Thabane, C. Daniel Mullins, Anthony D. Harris, Amber Wood Msn, Roman M. Natoli, Todd O. McKinley, William Obremskey, Phillip M. Mitchell, Jennifer E. Hagen, Marissa Pazik, Stephen J. Warner, Joshua L. Gary, Herman Johal, Jodi L. Gallant, Kyle J. Jeray, Stephanie L. Tanner, Justin Fowler, Sarah N. Pierrie, Robert O'Toole, Andrea L. Howe, Michael J. Prayson, Jennifer Jerele, Christina L. Boulton, Jason Lowe, Niloofar Dehghan, Michael D. McKee, Saam Morshed, Meir T. Marmor, Ernesto Guerra-Farfan, Yaiza Garcia-Sanchez, Francesc Marcano-Fernandez, Laia Martinez-Carreres, Nathan N. O'Hara, Shannon Dodds, David Pogorzelski, Sofia Bzovsky, Diane Heels-Ansdell, Olivia Paige Szasz, Gregory J. Della Rocca, Robert D. Zura, Lucas S. Marchand, Joan N. Hebden, Joseph T. Patterson, Christopher Lee, Lyndsay M. O'Hara, Debra Marvel, Jana E. Palmer, I. Leah Gitajn, Jean-Claude G. D'alleyrand, Jessica C. Rivera, Franca Mossuto, Manjari Joshi, Jeff Friedrich, Gordon Guyatt, P. J. Devereaux, Mohit Bhandari
Summary: This study compared the effect of aqueous 10% povidone-iodine and aqueous 4% chlorhexidine gluconate on the risk of surgical site infection in patients with open fractures requiring surgery. The results showed no significant difference between the two groups. Either aqueous 10% povidone-iodine or aqueous 4% chlorhexidine gluconate can be selected for skin antisepsis in patients with open fractures based on availability, contraindications, or cost.
Article
Public, Environmental & Occupational Health
S. J. Monstrey, D. Lepelletier, A. Simon, G. Touati, S. Vogt, F. Favalli
Summary: This study investigated the impact of different application techniques on the antiseptic activity of alcoholic povidone-iodine solution. The results showed significant antiseptic activity with all modes of application, and greater efficacy was achieved with back-and-forth friction method compared to concentric circle method. These findings suggest that application technique may influence antiseptic activity, and comparable application techniques should be considered when comparing the efficacy of different antiseptic substances.
JOURNAL OF HOSPITAL INFECTION
(2022)
Article
Reproductive Biology
Juan E. Romano, Renato G. Zanoni, Beatrice Mislei, Diego Bucci, Domenico Mion, Gaetano Mari
Summary: The study estimated the number of colonies forming units (CFU) in penile mucosa and semen and compared the effect of two antiseptic solutions used to reduce bacterial counts in those areas. The results showed that flushing the preputial cavity with 0.05% chlorhexidine digluconate or 1% povidone-iodine solution reduced the CFU counts in penile mucosa and semen.
Review
Nursing
Li Li, Yu Wang, Shouyan Wang
Summary: This study conducted a systematic review and meta-analysis to evaluate the efficacy of chlorhexidine and povidone-iodine in preventing postoperative surgical site infections (SSI) and relevant bacterial data. The results indicated that chlorhexidine was more effective than povidone-iodine in preventing SSI, and the two disinfectants had different effects on bacterial colonization depending on the type of incision.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2022)
Article
Ophthalmology
Seung Min Lee, Jong Ho Park, Chul Hun Jang, Iksoo Byon
Summary: Intravitreal injection of povidone-iodine was effective in treating VRE endophthalmitis, even at low concentrations. High-concentration intravitreal vancomycin injection can also be used to treat resistant strains within the safety threshold.
EXPERIMENTAL EYE RESEARCH
(2021)
Article
Agriculture, Dairy & Animal Science
Maurizio Isola, Cristina Piccinotti, Massimiliano Magro, Luca Fasolato, Fabio Vianello, Maria Luisa Menandro, Parastoo Memarian, Melissa Rossi, Maria Elena Falomo
Summary: Horse hooves can be susceptible to secondary infections, and effective disinfectants are crucial in preventing such complications. IA demonstrated strong bactericidal activity in vitro and enhanced the effectiveness of CHx and PI in hoof disinfection, showing potential applications in pre-surgical procedures for reducing infection risks.
Article
Ophthalmology
Ferhina S. Ali, Thomas L. Jenkins, Ranjodh S. Boparai, Anthony Obeid, Martha E. Ryan, Turner D. Wibblesman, Allen Chiang, Sunir J. Garg
Summary: The study compared the effects of using topical povidone-iodine and aqueous chlorhexidine on patient pain scores, ocular surface characteristics, and antimicrobial efficacy during intravitreal injections. Results showed that povidone-iodine caused greater ocular discomfort and corneal epitheliopathy, while aqueous chlorhexidine may be a better tolerated alternative.
OPHTHALMOLOGY RETINA
(2021)
Article
Medicine, General & Internal
Summary: A trial conducted in low-income and middle-income countries did not demonstrate benefits of 2% alcoholic chlorhexidine skin preparation compared with povidone-iodine, or triclosan-coated sutures compared with non-coated sutures, in preventing surgical site infections in cleancontaminated or contaminated or dirty surgical wounds. Both interventions are more costly than alternatives, and these results do not endorse routine use.
Article
Dermatology
Panfeng Wang, Dandan Wang, Lingqiao Zhang
Summary: This study conducted a systematic evaluation to assess the efficacy of chlorhexidine and povidone-iodine as primary components in preventing surgical site infection (SSI). The meta-analysis results indicated that chlorhexidine was more effective than povidone-iodine in reducing the incidence of surgical site wound infections, superficial SSIs, and deep SSIs.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Alina Chelmus-Burlacu, Eric Tang, Dragos Pieptu
Summary: This study evaluated the effects of chlorhexidine and povidone-iodine on cellular constructs and found that povidone-iodine had a greater inhibitory effect on cell migration and sprouting, although it had minimal effects at low concentrations.
Review
Dermatology
Dunyao Bai, Fan Zhou, Liuting Wu
Summary: Surgical site infections (SSIs) have a significant impact on patient health and healthcare costs. This meta-analysis examines the effectiveness of antiseptics, chlorhexidine and povidone-iodine, in reducing SSIs and concludes that chlorhexidine is more effective than povidone-iodine.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Public, Environmental & Occupational Health
Dorothea Doerfel, Matthias Maiwald, Georg Daeschlein, Gerald Mueller, Robert Hudek, Ojan Assadian, Gunter Kampf, Thomas Kohlmann, Julian Camill Harnoss, Axel Kramer
Summary: This study compared the effects of two antiseptics on skin microbiota, demonstrating that one antiseptic was more effective in removing anaerobic bacteria.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2021)
Article
Ophthalmology
Agni Malmin, Vilde M. Thomseth, Per T. Forland, Ayyad Z. Khan, Hanne B. Hetland, Xiangjun Chen, Inga-Britt K. Haugen, Tor P. Utheim, Vegard A. Forsaa
Summary: This study aimed to investigate the effects of serial intravitreal injections (IVIs) on the ocular surface and meibomian glands (MGs) in patients treated with anti-vascular endothelial growth factor (anti-VEGF) for neovascular age-related macular degeneration (nAMD). The results showed that repeated IVIs with preoperative povidone-iodine (PVP-I) application were associated with reduced MG loss, increased tear volume, and reduced signs of inflammation compared with fellow nontreated eyes.
Article
Ophthalmology
Seung Min Lee, Jong Ho Park, Su Youn Suh, Sang Min Lee, Iksoo Byon
Summary: Intravitreal administration of povidone-iodine demonstrated efficacy in treating Candida albicans endophthalmitis by reducing inflammation and fungal growth. However, the combination with voriconazole did not show a synergistic effect. The findings suggest that povidone-iodine may be a useful treatment option for this condition.
EXPERIMENTAL EYE RESEARCH
(2021)
Article
Anatomy & Morphology
Zumrut Ceren Ozduman, Burcu Oglakci, Mirac Dogan, Ceren Deger, Evrim Eliguzeloglu Dalkilic
Summary: This study compared the effect of different mouthwashes during the COVID-19 pandemic on the bond strength of universal adhesive to enamel. The results showed that in the self-etch mode, the group without mouthwash had significantly higher bond strength than other mouthwash groups; in the etch-and-rinse mode, teeth without mouthwash had significantly higher bond strength than the chlorhexidine and povidone-iodine groups.
MICROSCOPY RESEARCH AND TECHNIQUE
(2022)
