4.5 Article

Simulation study on X-ray phase contrast imaging with dual-phase gratings

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s11548-018-1872-x

Keywords

Phase contrast imaging; Talbot-Lau; Grating-based interferometry; Dual-phase grating

Funding

  1. Siemens Healthineers
  2. German Research Foundation (DFG)
  3. International Max Planck Research School for the Physics of Light
  4. Deutsche Forschungsgemeinschaft [289363653]

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PurposeTwo phase gratings in an X-ray grating interferometers can solve several technical challenges for clinical use of X-ray phase contrast. In this work, we adapt and evaluate this setup design to clinical X-ray sources and detectors in a simulation study.MethodsFor a given set of gratings, we optimize the remaining parameter space of a dual-phase grating setup using a numerical wave front simulation. The simulation results are validated with experimentally obtained visibility measurements on a setup with a microfocus tube and a clinical X-ray detector. We then confirm by simulation that the Lau condition for the G0 grating also holds for two phase gratings. Furthermore, we use a G0 grating with a fixed period to search for periods of matching phase grating configurations.ResultsSimulated and experimental visibilities agree very well. We show that the Lau condition for a dual-phase grating setup requires the interference patterns of the first phase grating to constructively overlay at the second phase grating. Furthermore, a total of three setup variants for given G0 periods were designed with the simulation, resulting in visibilities between 4.5 and 9.1%.ConclusionDual-phase gratings can be used and optimized for a medical X-ray source and detector. The obtained visibilities are somewhat lower than for other Talbot-Lau interferometers and are a tradeoff between setup length and spatial resolution (or additional phase stepping, respectively). However, these disadvantage appears minor compared to the overall better photon statistics, and the fact that dual-phase grating setups can be expected to scale to higher X-ray energies.

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