Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts

DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation

(2018) Qian Xiao et al.   NATURE MEDICINE

Differential effects on lung and bone metastasis of breast cancer by Wnt signalling inhibitor DKK1

(2017) Xueqian Zhuang et al.   NATURE CELL BIOLOGY

YAP/TAZ at the Roots of Cancer

(2016) Francesca Zanconato et al.   CANCER CELL

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Force Matters: Biomechanical Regulation of Cell Invasion and Migration in Disease

(2016) FuiBoon Kai et al.   TRENDS IN CELL BIOLOGY

HSF1: Guardian of Proteostasis in Cancer

(2016) Chengkai Dai et al.   TRENDS IN CELL BIOLOGY

Microenvironmental regulation of therapeutic response in cancer

(2015) Florian Klemm et al.   TRENDS IN CELL BIOLOGY

Dickkopf-3, a Tissue-Derived Modulator of Local T-Cell Responses

(2015) Michael Meister et al.   Frontiers in Immunology

The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy

(2014) Ruth Scherz-Shouval et al.   CELL

YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

(2014) Luca Azzolin et al.   CELL

Fibroblast heterogeneity in the cancer wound

(2014) Daniel Öhlund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

(2013) Fernando Calvo et al.   NATURE CELL BIOLOGY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles

(2012) Julia Tchou et al.   BMC Medical Genomics

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

(2012) Alexandre Calon et al.   CANCER CELL

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

DKK2 Mediates Osteolysis, Invasiveness, and Metastatic Spread in Ewing Sarcoma

(2012) K. Hauer et al.   CANCER RESEARCH

Role of TAZ as Mediator of Wnt Signaling

(2012) Luca Azzolin et al.   CELL

Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients

(2012) Balázs Győrffy et al.   ENDOCRINE-RELATED CANCER

Modeling Colon Adenocarcinomas in Vitro

(2011) Helmut Dolznig et al.   AMERICAN JOURNAL OF PATHOLOGY

Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

(2011) Jacky G. Goetz et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

(2011) Mina J Bissell et al.   NATURE MEDICINE

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF -TRCP

(2010) B. Zhao et al.   GENES & DEVELOPMENT

Analysis of Dickkopf3 interactions with Wnt signaling receptors

(2010) Rei E. I. Nakamura et al.   GROWTH FACTORS

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Experimentally Derived Metastasis Gene Expression Profile Predicts Recurrence and Death in Patients With Colon Cancer

(2009) J. Joshua Smith et al.   GASTROENTEROLOGY

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

(2009) David A. Barbie et al.   NATURE

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Stromal gene expression predicts clinical outcome in breast cancer

(2008) Greg Finak et al.   NATURE MEDICINE

Intravital imaging of metastatic behavior through a mammary imaging window

(2008) Dmitriy Kedrin et al.   NATURE METHODS