Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics

Understanding the Connection between Nanoparticle Uptake and Cancer Treatment Efficacy using Mathematical Modeling

(2018) Terisse A. Brocato et al.   Scientific Reports

Impact of silica nanoparticle surface chemistry on protein corona formation and consequential interactions with biological cells

(2017) Andréa Kurtz-Chalot et al.   Materials Science & Engineering C-Materials for Biological Applications

Mesoporous Silica and Organosilica Nanoparticles: Physical Chemistry, Biosafety, Delivery Strategies, and Biomedical Applications

(2017) Jonas G. Croissant et al.   Advanced Healthcare Materials

Mesoporous Silica Nanoparticle-Supported Lipid Bilayers (Protocells) for Active Targeting and Delivery to Individual Leukemia Cells

(2016) Paul N. Durfee et al.   ACS Nano

Radiolabeling, whole-body single photon emission computed tomography/computed tomography imaging, and pharmacokinetics of carbon nanohorns in mice

(2016) Minfang Zhang et al.   International Journal of Nanomedicine

Ligand-targeted theranostic nanomedicines against cancer

(2016) Virginia J. Yao et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

(2016) Yi-Nan Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Mechanism of hard-nanomaterial clearance by the liver

(2016) Kim M. Tsoi et al.   NATURE MATERIALS

Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release

(2016) Hitomi Hosoya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protocells: Modular Mesoporous Silica Nanoparticle-Supported Lipid Bilayers for Drug Delivery

(2016) Kimberly S. Butler et al.   Small

Theory and Experimental Validation of a Spatio-temporal Model of Chemotherapy Transport to Enhance Tumor Cell Kill

(2016) Zhihui Wang et al.   PLoS Computational Biology

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Distribution of Systemically Administered Nanoparticles Reveals a Size-Dependent Effect Immediately following Cardiac Ischaemia-Reperfusion Injury

(2016) David J. Lundy et al.   Scientific Reports

Mesoporous silica as topical nanocarriers for quercetin: characterization and in vitro studies

(2015) Simona Sapino et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Predictive Modeling of Drug Response in Non-Hodgkin’s Lymphoma

(2015) Hermann B. Frieboes et al.   PLoS One

A Novel, Patient-Specific Mathematical Pathology Approach for Assessment of Surgical Volume: Application to Ductal Carcinomain situof The Breast

(2015) Mary E. Edgerton et al.   Analytical Cellular Pathology

Particle Margination and Its Implications on Intravenous Anticancer Drug Delivery

(2014) Erik Carboni et al.   AAPS PHARMSCITECH

Transport properties of pancreatic cancer describe gemcitabine delivery and response

(2014) Eugene J. Koay et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe

(2014) E. Phillips et al.   Science Translational Medicine

Margination of micro- and nano-particles in blood flow and its effect on drug delivery

(2014) Kathrin Müller et al.   Scientific Reports

Mechanistic Modeling Identifies Drug-Uptake History as Predictor of Tumor Drug Resistance and Nano-Carrier-Mediated Response

(2013) Jennifer Pascal et al.   ACS Nano

Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology

(2013) Nicolas Bertrand et al.   ADVANCED DRUG DELIVERY REVIEWS

The absorption, distribution, excretion and toxicity of mesoporous silica nanoparticles in mice following different exposure routes

(2013) Changhui Fu et al.   BIOMATERIALS

In Search of the Chemical Basis of the Hemolytic Potential of Silicas

(2013) Cristina Pavan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

In vivo distribution and antitumor activity of doxorubicin-loaded N-isopropylacrylamide-co-methacrylic acid coated mesoporous silica nanoparticles and safety evaluation

(2013) Yanzuo Chen et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Re-examining the Size/Charge Paradigm: Differing in Vivo Characteristics of Size- and Charge-Matched Mesoporous Silica Nanoparticles

(2013) Jason L. Townson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic development of the protein corona on silica nanoparticles: composition and role in toxicity

(2013) Ninell P. Mortensen et al.   Nanoscale

Impact of Diffusion Barriers to Small Cytotoxic Molecules on the Efficacy of Immunotherapy in Breast Cancer

(2013) Hiranmoy Das et al.   PLoS One

Mechanistic patient-specific predictive correlation of tumor drug response with microenvironment and perfusion measurements

(2013) J. Pascal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the near-wall accumulation of injectable particles in the microcirculation: smaller is not better

(2013) Tae-Rin Lee et al.   Scientific Reports

In vivo biodistribution and pharmacokinetics of silica nanoparticles as a function of geometry, porosity and surface characteristics

(2012) Tian Yu et al.   JOURNAL OF CONTROLLED RELEASE

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

The Shape Effect of Mesoporous Silica Nanoparticles on Biodistribution, Clearance, and Biocompatibility in Vivo

(2011) Xinglu Huang et al.   ACS Nano

Use of Size and a Copolymer Design Feature To Improve the Biodistribution and the Enhanced Permeability and Retention Effect of Doxorubicin-Loaded Mesoporous Silica Nanoparticles in a Murine Xenograft Tumor Model

(2011) Huan Meng et al.   ACS Nano

Particle size-dependent and surface charge-dependent biodistribution of gold nanoparticles after intravenous administration

(2011) Stephanie Hirn et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Bone marrow-targeted liposomal carriers

(2011) Keitaro Sou et al.   Expert Opinion on Drug Delivery

Ultrastable, Redispersible, Small, and Highly Organomodified Mesoporous Silica Nanotherapeutics

(2011) Yu-Shen Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake

(2011) Carl D. Walkey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In vivo tumor suppression efficacy of mesoporous silica nanoparticles-based drug-delivery system: enhanced efficacy by folate modification

(2011) Jie Lu et al.   Nanomedicine-Nanotechnology Biology and Medicine

In Vivo Biodistribution and Clearance Studies Using Multimodal Organically Modified Silica Nanoparticles

(2010) Rajiv Kumar et al.   ACS Nano

Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles

(2010) Jeffrey S. Souris et al.   BIOMATERIALS

Biodistribution, pharmacokinetics and metabolism of interleukin-1 receptor antagonist (IL-1RA) using [18F]-IL1RA and PET imaging in rats

(2010) C Cawthorne et al.   BRITISH JOURNAL OF PHARMACOLOGY

Molecular tracers for the PET and SPECT imaging of disease

(2010) Sally L. Pimlott et al.   CHEMICAL SOCIETY REVIEWS

Impacts of Mesoporous Silica Nanoparticle Size, Pore Ordering, and Pore Integrity on Hemolytic Activity

(2010) Yu-Shen Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In vivo Biodistribution and Urinary Excretion of Mesoporous Silica Nanoparticles: Effects of Particle Size and PEGylation

(2010) Qianjun He et al.   Small

The association of silicon microparticles with endothelial cells in drug delivery to the vasculature

(2009) Rita E. Serda et al.   BIOMATERIALS

Pharmacokinetics and tumor dynamics of the nanoparticle IT-101 from PET imaging and tumor histological measurements

(2009) T. Schluep et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers☆

(2008) I SLOWING et al.   ADVANCED DRUG DELIVERY REVIEWS

In Vivo Study of Biodistribution and Urinary Excretion of Surface-Modified Silica Nanoparticles

(2008) Xiaoxiao He et al.   ANALYTICAL CHEMISTRY

Quantitative Serial Imaging of an 124I Anti-CEA Monoclonal Antibody in Tumor-Bearing Mice

(2008) James R. Bading et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Pharmacokinetics and Biodistribution of Nanoparticles

(2008) Shyh-Dar Li et al.   MOLECULAR PHARMACEUTICS

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS

The margination propensity of spherical particles for vascular targeting in the microcirculation

(2008) Francesco Gentile et al.   JOURNAL OF NANOBIOTECHNOLOGY