Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides
Authors
Keywords
-
Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-12-28
DOI
10.1038/s41467-018-07826-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Neglected tropical diseases: progress towards addressing the chronic pandemic
- (2017) David H Molyneux et al. LANCET
- A Test-and-Not-Treat Strategy for Onchocerciasis in Loa loa–Endemic Areas
- (2017) Joseph Kamgno et al. NEW ENGLAND JOURNAL OF MEDICINE
- Perturbed cholesterol and vesicular trafficking associated with dengue blocking in Wolbachia-infected Aedes aegypti cells
- (2017) Vincent Geoghegan et al. Nature Communications
- Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa
- (2017) Peter U. Fischer et al. PLoS Neglected Tropical Diseases
- Discovery of Second Generation Reversible Covalent DPP1 Inhibitors Leading to an Oxazepane Amidoacetonitrile Based Clinical Candidate (AZD7986)
- (2016) Kevin Doyle et al. JOURNAL OF MEDICINAL CHEMISTRY
- Factors Associated with Ivermectin Non-Compliance and Its Potential Role in Sustaining Onchocerca volvulus Transmission in the West Region of Cameroon
- (2016) Laura Senyonjo et al. PLoS Neglected Tropical Diseases
- Doxycycline Leads to Sterility and Enhanced Killing of FemaleOnchocerca volvulusWorms in an Area With Persistent Microfilaridermia After Repeated Ivermectin Treatment: A Randomized, Placebo-Controlled, Double-Blind Trial
- (2015) Alexander Yaw Debrah et al. CLINICAL INFECTIOUS DISEASES
- DataWarrior: An Open-Source Program For Chemistry Aware Data Visualization And Analysis
- (2015) Thomas Sander et al. Journal of Chemical Information and Modeling
- Sm16, a major component of Schistosoma mansoni cercarial excretory/secretory products, prevents macrophage classical activation and delays antigen processing
- (2015) David E Sanin et al. Parasites & Vectors
- Therapeutic Efficacy and Macrofilaricidal Activity of Doxycycline for the Treatment of River Blindness
- (2014) Martin Walker et al. CLINICAL INFECTIOUS DISEASES
- Optimization of Pyrrolamide Topoisomerase II Inhibitors Toward Identification of an Antibacterial Clinical Candidate (AZD5099)
- (2014) Gregory S. Basarab et al. JOURNAL OF MEDICINAL CHEMISTRY
- The role of modern drug discovery in the fight against neglected and tropical diseases
- (2014) Jeremy N. Burrows et al. MedChemComm
- Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis
- (2014) Kelly L. Johnston et al. International Journal for Parasitology-Drugs and Drug Resistance
- Anti-Wolbachia drug discovery and development: safe macrofilaricides for onchocerciasis and lymphatic filariasis
- (2013) MARK J. TAYLOR et al. PARASITOLOGY
- Impact of Lipophilic Efficiency on Compound Quality
- (2012) Ákos Tarcsay et al. JOURNAL OF MEDICINAL CHEMISTRY
- P. falciparum In Vitro Killing Rates Allow to Discriminate between Different Antimalarial Mode-of-Action
- (2012) Laura M. Sanz et al. PLoS One
- Extended-Connectivity Fingerprints
- (2010) David Rogers et al. Journal of Chemical Information and Modeling
- New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
- (2010) Jonathan B. Baell et al. JOURNAL OF MEDICINAL CHEMISTRY
- Using an intravenous catheter to carry out abdominal lavage in the gerbil
- (2010) Kathryn G. Griffiths et al. LAB ANIMAL
- Macrofilaricidal Activity after Doxycycline Only Treatment of Onchocerca volvulus in an Area of Loa loa Co-Endemicity: A Randomized Controlled Trial
- (2010) Joseph D. Turner et al. PLoS Neglected Tropical Diseases
- WolbachiaLipoprotein Stimulates Innate and Adaptive Immunity through Toll-like Receptors 2 and 6 to Induce Disease Manifestations of Filariasis
- (2009) Joseph D. Turner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started