Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans

Circulating T FH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity

(2018) Marios Koutsakos et al.   Science Translational Medicine

Influenza

(2018) Florian Krammer et al.   Nature Reviews Disease Primers

Lack of Heterologous Cross-reactivity toward HLA-A*02:01 Restricted Viral Epitopes Is Underpinned by Distinct αβT Cell Receptor Signatures

(2016) Emma J. Grant et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

(2016) David K. Cole et al.   JOURNAL OF CLINICAL INVESTIGATION

A Role of Influenza Virus Exposure History in Determining Pandemic Susceptibility and CD8+T Cell Responses

(2016) Sergio M. Quiñones-Parra et al.   JOURNAL OF VIROLOGY

Hydrophobic CDR3 residues promote the development of self-reactive T cells

(2016) Brian D Stadinski et al.   NATURE IMMUNOLOGY

Molecular basis for universal HLA-A*0201–restricted CD8+T-cell immunity against influenza viruses

(2016) Sophie A. Valkenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human influenza viruses and CD8 + T cell responses

(2016) Emma J Grant et al.   Current Opinion in Virology

T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules

(2015) Jamie Rossjohn et al.   Annual Review of Immunology

T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+Cells

(2015) Melissa J. Rist et al.   JOURNAL OF IMMUNOLOGY

MX1: a bending-magnet crystallography beamline serving both chemical and macromolecular crystallography communities at the Australian Synchrotron

(2015) Nathan Philip Cowieson et al.   JOURNAL OF SYNCHROTRON RADIATION

Oseltamivir Prophylaxis Reduces Inflammation and Facilitates Establishment of Cross-Strain Protective T Cell Memory to Influenza Viruses

(2015) Nicola L. Bird et al.   PLoS One

Deconstructing the Peptide-MHC Specificity of T Cell Recognition

(2014) Michael E. Birnbaum et al.   CELL

Recognition of Distinct Cross-Reactive Virus-Specific CD8+ T Cells Reveals a Unique TCR Signature in a Clinical Setting

(2014) T. H. O. Nguyen et al.   JOURNAL OF IMMUNOLOGY

Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities

(2014) S. Quinones-Parra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Memory CD4 T Cell-Mediated Immunity against Influenza A Virus: More than a Little Helpful

(2013) K. Kai McKinstry et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8+ T Cells

(2013) Kristin Ladell et al.   IMMUNITY

Nucleoprotein of influenza A virus is a major target of immunodominant CD8+ T-cell responses

(2013) Emma Grant et al.   IMMUNOLOGY AND CELL BIOLOGY

HLA Peptide Length Preferences Control CD8+ T Cell Responses

(2013) M. J. Rist et al.   JOURNAL OF IMMUNOLOGY

Human Cytotoxic T Lymphocytes Directed to Seasonal Influenza A Viruses Cross-React with the Newly Emerging H7N9 Virus

(2013) C. E. van de Sandt et al.   JOURNAL OF VIROLOGY

Cellular immune correlates of protection against symptomatic pandemic influenza

(2013) Saranya Sridhar et al.   NATURE MEDICINE

Acute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptides

(2013) Sophie A. Valkenburg et al.   Nature Communications

Cooperativity Between CD8+ T Cells, Non-Neutralizing Antibodies, and Alveolar Macrophages Is Important for Heterosubtypic Influenza Virus Immunity

(2013) Brian J. Laidlaw et al.   PLoS Pathogens

Exploiting structure similarity in refinement: automated NCS and target-structure restraints inBUSTER

(2012) Oliver S. Smart et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Human T-cells directed to seasonal influenza A virus cross-react with 2009 pandemic influenza A (H1N1) and swine-origin triple-reassortant H3N2 influenza viruses

(2012) M. L. B. Hillaire et al.   JOURNAL OF GENERAL VIROLOGY

Early Priming Minimizes the Age-Related Immune Compromise of CD8+ T Cell Diversity and Function

(2012) Sophie A. Valkenburg et al.   PLoS Pathogens

A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

(2011) Linda Wooldridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fitness Costs and Diversity of the Cytotoxic T Lymphocyte (CTL) Response Determine the Rate of CTL Escape during Acute and Chronic Phases of HIV Infection

(2011) V. V. Ganusov et al.   JOURNAL OF VIROLOGY

Systematic identification of immunodominant CD8+ T-cell responses to influenza A virus in HLA-A2 individuals

(2011) C. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Fixing an irrelevant TCRα chain reveals the importance of TCRβ diversity for optimal TCRαβ pairing and function of virus-specific CD8+ T cells

(2010) Sophie A. Valkenburg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-React against 2009 Pandemic H1N1 Influenza Virus

(2010) W. Tu et al.   JOURNAL OF VIROLOGY

Cross-reactive CD8+T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses

(2010) Stephanie Gras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

(2010) Sophie A. Valkenburg et al.   PLoS Pathogens

The Shaping of T Cell Receptor Recognition by Self-Tolerance

(2009) Stephanie Gras et al.   IMMUNITY

T Cell Allorecognition via Molecular Mimicry

(2009) Whitney A. Macdonald et al.   IMMUNITY

Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition

(2009) Julia K. Archbold et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structural Bases for the Affinity-Driven Selection of a Public TCR against a Dominant Human Cytomegalovirus Epitope

(2009) S. Gras et al.   JOURNAL OF IMMUNOLOGY

T-Cell Tolerance for Variability in an HLA Class I-Presented Influenza A Virus Epitope

(2009) A. Wahl et al.   JOURNAL OF VIROLOGY

Cross-Recognition of Avian H5N1 Influenza Virus by Human Cytotoxic T-Lymphocyte Populations Directed to Human Influenza A Virus

(2008) J. H. C. M. Kreijtz et al.   JOURNAL OF VIROLOGY

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH