Cardiac Progenitor Cell–Derived Extracellular Vesicles Reduce Infarct Size and Associate with Increased Cardiovascular Cell Proliferation

Stem cell-inspired secretome-rich injectable hydrogel to repair injured cardiac tissue

(2018) Renae Waters et al.   Acta Biomaterialia

miRNAs that Induce Human Cardiomyocyte Proliferation Converge on the Hippo Pathway

(2018) Marta Diez-Cuñado et al.   Cell Reports

Hippo pathway deficiency reverses systolic heart failure after infarction

(2017) John P. Leach et al.   NATURE

Dystrophin–glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation

(2017) Yuka Morikawa et al.   NATURE

Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model

(2017) Shi-Cong Tao et al.   Theranostics

Exosomes derived from platelet-rich plasma promote the re-epithelization of chronic cutaneous wounds via activation of YAP in a diabetic rat model

(2017) Shang-Chun Guo et al.   Theranostics

Myocardial reparative functions of exosomes from mesenchymal stem cells are enhanced by hypoxia treatment of the cells via transferring microRNA-210 in an nSMase2-dependent way

(2017) Jinyun Zhu et al.   Artificial Cells Nanomedicine and Biotechnology

Regulation of Tissue Growth by the Mammalian Hippo Signaling Pathway

(2017) Kevin I. Watt et al.   Frontiers in Physiology

A Deep Proteome Analysis Identifies the Complete Secretome as the Functional Unit of Human Cardiac Progenitor CellsNovelty and Significance

(2016) Sudhish Sharma et al.   CIRCULATION RESEARCH

Exosomes derived from dendritic cells improve cardiac function via activation of CD4+ T lymphocytes after myocardial infarction

(2016) Haibo Liu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Exosomes from Cardiomyocyte Progenitor Cells and Mesenchymal Stem Cells Stimulate Angiogenesis Via EMMPRIN

(2016) Krijn R. Vrijsen et al.   Advanced Healthcare Materials

In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior

(2015) Anoek Zomer et al.   CELL

Dynamics of Cell Generation and Turnover in the Human Heart

(2015) Olaf Bergmann et al.   CELL

Embryonic Stem Cell-Derived Exosomes Promote Endogenous Repair Mechanisms and Enhance Cardiac Function Following Myocardial Infarction

(2015) M. Khan et al.   CIRCULATION RESEARCH

Plasma Exosomes Protect the Myocardium From Ischemia-Reperfusion Injury

(2015) Jose M. Vicencio et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Yes-associated protein regulates the growth of human non-small cell lung cancer in response to matrix stiffness

(2015) YONGGANG YUAN et al.   Molecular Medicine Reports

Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction

(2014) L. Barile et al.   CARDIOVASCULAR RESEARCH

Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas

(2014) Alizée Boin et al.   NEURO-ONCOLOGY

ENDOGLIN Is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-Induced Angiogenesis

(2014) Zhen Liu et al.   PLoS One

Exosomes as Critical Agents of Cardiac Regeneration Triggered by Cell Therapy

(2014) Ahmed Gamal-Eldin Ibrahim et al.   Stem Cell Reports

miR-375 Inhibits Proliferation of Mouse Pancreatic Progenitor Cells by Targeting YAP1

(2013) Zhen-Wu Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Hippo signaling impedes adult heart regeneration

(2013) T. Heallen et al.   DEVELOPMENT

Meis1 regulates postnatal cardiomyocyte cell cycle arrest

(2013) Ahmed I. Mahmoud et al.   NATURE

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury

(2013) Fatih Arslan et al.   Stem Cell Research

Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression

(2012) A. Bobrie et al.   CANCER RESEARCH

MicroRNA-214 inhibits angiogenesis by targeting Quaking and reducing angiogenic growth factor release

(2012) Alain van Mil et al.   CARDIOVASCULAR RESEARCH

A fibronectin-fibrinogen-tropoelastin coating reduces smooth muscle cell growth but improves endothelial cell function

(2012) Claudia Tersteeg et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Low oxygen tension positively influences cardiomyocyte progenitor cell function

(2011) Angelique A. M. van Oorschot et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cardiomyogenic differentiation-independent improvement of cardiac function by human cardiomyocyte progenitor cell injection in ischaemic mouse hearts

(2011) Melina C. den Haan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction

(2011) Leo Timmers et al.   Stem Cell Research

New insights into paracrine mechanisms of human cardiac progenitor cells

(2010) Hagen Maxeiner et al.   EUROPEAN JOURNAL OF HEART FAILURE

Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium

(2009) Anke M. Smits et al.   CARDIOVASCULAR RESEARCH

Gastric cancer exosomes promote tumour cell proliferation through PI3K/Akt and MAPK/ERK activation

(2009) J.-L. Qu et al.   DIGESTIVE AND LIVER DISEASE

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Human cardiomyocyte progenitor cells differentiate into functional mature cardiomyocytes: an in vitro model for studying human cardiac physiology and pathophysiology

(2009) Anke M Smits et al.   Nature Protocols

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

TGF-β1 induces efficient differentiation of human cardiomyocyte progenitor cells into functional cardiomyocytes in vitro

(2008) Marie-José Goumans et al.   Stem Cell Research

Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium

(2008) Leo Timmers et al.   Stem Cell Research