Glycyl Radical Enzyme-Associated Microcompartments: Redox-Replete Bacterial Organelles

Characterization of 1,2-Propanediol Dehydratases Reveals Distinct Mechanisms for B12-Dependent and Glycyl Radical Enzymes

(2018) Benjamin J. Levin et al.   BIOCHEMISTRY

A Bacterial Microcompartment Is Used for Choline Fermentation by Escherichia coli 536

(2018) Taylor I. Herring et al.   JOURNAL OF BACTERIOLOGY

Discovery of enzymes for toluene synthesis from anoxic microbial communities

(2018) Harry R. Beller et al.   Nature Chemical Biology

Bacterial microcompartments

(2018) Cheryl A. Kerfeld et al.   NATURE REVIEWS MICROBIOLOGY

Discovering radical-dependent enzymes in the human gut microbiota

(2018) Benjamin J Levin et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Assembly principles and structure of a 6.5-MDa bacterial microcompartment shell

(2017) Markus Sutter et al.   SCIENCE

A systems-level model reveals that 1,2-Propanediol utilization microcompartments enhance pathway flux through intermediate sequestration

(2017) Christopher M. Jakobson et al.   PLoS Computational Biology

In Vitro Characterization and Concerted Function of Three Core Enzymes of a Glycyl Radical Enzyme - Associated Bacterial Microcompartment

(2017) Jan Zarzycki et al.   Scientific Reports

1,2-Propanediol Dehydration inRoseburia inulinivorans

(2016) Joseph W. LaMattina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Function of a Bacterial Microcompartment Shell Protein Engineered to Bind a [4Fe-4S] Cluster

(2016) Clément Aussignargues et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Employing bacterial microcompartment technology to engineer a shell-free enzyme-aggregate for enhanced 1,2-propanediol production in Escherichia coli

(2016) Matthew J. Lee et al.   METABOLIC ENGINEERING

Insight into Coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans

(2016) Laura R. Tuck et al.   Scientific Reports

The Structural Basis of Coenzyme A Recycling in a Bacterial Organelle

(2016) Onur Erbilgin et al.   PLOS BIOLOGY

Bioinformatic Characterization of Glycyl Radical Enzyme-Associated Bacterial Microcompartments

(2015) Jan Zarzycki et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Auxiliary iron–sulfur cofactors in radical SAM enzymes

(2015) Nicholas D. Lanz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Anaerobic choline metabolism in microcompartments promotes growth and swarming of P roteus mirabilis

(2015) Eleanor Jameson et al.   ENVIRONMENTAL MICROBIOLOGY

Structure and Function of CutC Choline Lyase from Human Microbiota BacteriumKlebsiella pneumoniae

(2015) Gints Kalnins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial microcompartments and the modular construction of microbial metabolism

(2015) Cheryl A. Kerfeld et al.   TRENDS IN MICROBIOLOGY

Characterization and Detection of a Widely Distributed Gene Cluster That Predicts Anaerobic Choline Utilization by Human Gut Bacteria

(2015) Ana Martínez-del Campo et al.   mBio

Regulation of fucose and 1,2-propanediol utilization by Salmonella enterica serovar Typhimurium

(2015) Lena Staib et al.   Frontiers in Microbiology

Characterization of Choline Trimethylamine-Lyase Expands the Chemistry of Glycyl Radical Enzymes

(2014) Smaranda Craciun et al.   ACS Chemical Biology

Glycyl radical activating enzymes: Structure, mechanism, and substrate interactions

(2014) Krista A. Shisler et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Identification of a Unique Fe-S Cluster Binding Site in a Glycyl-Radical Type Microcompartment Shell Protein

(2014) Michael C. Thompson et al.   JOURNAL OF MOLECULAR BIOLOGY

Solution Structure of a Bacterial Microcompartment Targeting Peptide and Its Application in the Construction of an Ethanol Bioreactor

(2014) Andrew D. Lawrence et al.   ACS Synthetic Biology

A Taxonomy of Bacterial Microcompartment Loci Constructed by a Novel Scoring Method

(2014) Seth D. Axen et al.   PLoS Computational Biology

Flavodoxin cofactor binding induces structural changes that are required for protein–protein interactions with NADP+ oxidoreductase and pyruvate formate-lyase activating enzyme

(2013) Adam V. Crain et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

A rapid flow cytometry assay for the relative quantification of protein encapsulation into bacterial microcompartments

(2013) Edward Y. Kim et al.   Biotechnology Journal

Biogenesis of a Bacterial Organelle: The Carboxysome Assembly Pathway

(2013) Jeffrey C. Cameron et al.   CELL

Pyruvate Formate-lyase and Its Activation by Pyruvate Formate-lyase Activating Enzyme

(2013) Adam V. Crain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of a Bacterial Microcompartment in the Metabolism of Fucose and Rhamnose by Clostridium phytofermentans

(2013) Elsa Petit et al.   PLoS One

Elucidating Essential Role of Conserved Carboxysomal Protein CcmN Reveals Common Feature of Bacterial Microcompartment Assembly

(2012) James N. Kinney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineered Protein Nano-Compartments for Targeted Enzyme Localization

(2012) Swati Choudhary et al.   PLoS One

The PduQ Enzyme Is an Alcohol Dehydrogenase Used to Recycle NAD+ Internally within the Pdu Microcompartment of Salmonella enterica

(2012) Shouqiang Cheng et al.   PLoS One

Interactions between the termini of lumen enzymes and shell proteins mediate enzyme encapsulation into bacterial microcompartments

(2012) C. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

(2012) S. Craciun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of PduT, a trimeric bacterial microcompartment protein with a 4Fe–4S cluster-binding site

(2011) Allan Pang et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Insights into Radical Generation by the Radical SAM Superfamily

(2011) Jessica L. Vey et al.   CHEMICAL REVIEWS

The N-Terminal Region of the Medium Subunit (PduD) Packages Adenosylcobalamin-Dependent Diol Dehydratase (PduCDE) into the Pdu Microcompartment

(2011) C. Fan et al.   JOURNAL OF BACTERIOLOGY

Characterization of the PduS Cobalamin Reductase of Salmonella enterica and Its Role in the Pdu Microcompartment

(2010) S. Cheng et al.   JOURNAL OF BACTERIOLOGY

Crystal Structures of Ethanolamine Ammonia-lyase Complexed with Coenzyme B12Analogs and Substrates

(2010) Naoki Shibata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insight into the Mechanisms of Transport across theSalmonella entericaPdu Microcompartment Shell

(2010) Christopher S. Crowley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterisation of PduS, the pdu Metabolosome Corrin Reductase, and Evidence of Substructural Organisation within the Bacterial Microcompartment

(2010) Joshua B. Parsons et al.   PLoS One

Dihydroflavin-driven Adenosylation of 4-Coordinate Co(II) Corrinoids

(2009) Paola E. Mera et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Structural Analysis of a Novel Carboxysome Shell Protein with Implications for Metabolite Transport

(2009) Michael G. Klein et al.   JOURNAL OF MOLECULAR BIOLOGY

Choline: an essential nutrient for public health

(2009) Steven H Zeisel et al.   NUTRITION REVIEWS

Rapid Pathway Evolution Facilitated by Horizontal Gene Transfers across Prokaryotic Lineages

(2009) Wataru Iwasaki et al.   PLoS Genetics

Biochemical and Structural Insights into Bacterial Organelle Form and Biogenesis

(2008) Joshua B. Parsons et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for glycyl radical formation by pyruvate formate-lyase activating enzyme

(2008) J. L. Vey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic-Level Models of the Bacterial Carboxysome Shell

(2008) S. Tanaka et al.   SCIENCE