Review
Psychiatry
Jessica P. Y. Hua, Samantha V. Abram, Judith M. Ford
Summary: This study provides an updated systematic review on the efficacy and tolerability of cerebellar stimulation in mitigating symptoms of schizophrenia. The results suggest that cerebellar stimulation can alleviate certain clinical symptoms and improve brain connectivity and neuro-oscillations in schizophrenia. However, there is no consistent evidence for cognitive improvements following cerebellar stimulation.
FRONTIERS IN PSYCHIATRY
(2022)
Review
Behavioral Sciences
Pablo Solana, Julio Santiago
Summary: According to the embodied cognition view, comprehending action-related language requires the participation of sensorimotor processes. While most studies support this view, a significant portion of them lack statistical power and show signs of publication bias.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Review
Clinical Neurology
Giordano D'Urso, Elena Toscano, Annarita Barone, Mario Palermo, Bernardo Dell'Osso, Giorgio Di Lorenzo, Antonio Mantovani, Giovanni Martinotti, Michele Fornaro, Felice Iasevoli, Andrea de Bartolomeis
Summary: Despite multiple available treatments for bipolar depression, many patients do not respond well. Transcranial direct current stimulation (tDCS) has shown promise in treating resistant cases, although further research is needed to determine optimal dosing, timing, and safety considerations.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2023)
Article
Anesthesiology
Guillermo Garcia-Barajas, Diego Serrano-Munoz, Julio Gomez-Soriano, Juan Avendano-Coy, Josue Fernandez-Carnero, Alvaro Megia Garcia, Antonio Segura-Fragosa, Julian Taylor
Summary: The study aimed to assess the effects of DCS applied to the SO region on pain perception, finding that neither SO-DCS nor M1-DCS enhanced heterotopic CPM but both showed significant inhibitory effects on tonic cold pain. Further confirmation is needed on the general effects of active DCS compared to sham on tonic cold pain.
Article
Cell Biology
Tatsuro Kohno, Kaori Takaki, Kaori Kishita, Kazunori Mitsutake, Nozomu Tofuku, Iwao Kishita
Summary: AIT (R) (AT-04) has been shown to have significant analgesic effects on neuropathic pain. The study revealed the mechanism of action of AT-04 in alleviating pain, involving the descending pain modulatory system and the opioid analgesic system.
CELLULAR AND MOLECULAR NEUROBIOLOGY
(2023)
Review
Endocrinology & Metabolism
Xiaoli Liao, Miao Chen, Yamin Li
Summary: The present study aimed to review evidence from postmortem brain and PET studies on the role of glia induced neuroinflammation in the pathogenesis of ASD. The findings from postmortem studies showed increased microglial number and density, as well as increased GFAP protein and mRNA expression in ASD subjects. However, the outcomes of PET studies were inconsistent, with one reporting increased TSPO expression and two reporting decreased TSPO expression in ASD subjects.
FRONTIERS IN NEUROENDOCRINOLOGY
(2023)
Article
Education & Educational Research
Wendy J. Rodgers, Hannah Morris-Mathews, John Elwood Romig, Elizabeth Bettini
Summary: Classroom observation research is crucial in the field of education for students with disabilities, but many studies do not provide evidence to support the validity of observation instruments. Findings indicate that while reporting levels of evidence have remained relatively constant over time, there has been a consistent decrease in the number of observations per teacher and a significant increase in reporting teacher participant characteristics.
REVIEW OF EDUCATIONAL RESEARCH
(2022)
Article
Astronomy & Astrophysics
Gergely Hajdu, Grzegorz Pietrzynski, Johanna Jurcsik, Marcio Catelan, Paulina Karczmarek, Bogumil Pilecki, Igor Soszynski, Andrzej Udalski, Ian B. Thompson
Summary: This study identifies 87 candidates for RR Lyrae variable stars in binary systems, with orbital periods predominantly above 1000 days and peak occurrence rate between 3000 and 4000 days. The eccentricities of these candidates are concentrated between 0.25 and 0.3, with a trimodal distribution of mass functions suggesting the presence of three distinct groups of companions.
ASTROPHYSICAL JOURNAL
(2021)
Article
Green & Sustainable Science & Technology
Jose de Lucio, Francisco Seijo
Summary: Our research indicates that initiatives in biosphere reserves can enhance community resilience, but governmental obstacles and institutional legacy effects continue to constrain the ability of BR managers.
SUSTAINABILITY SCIENCE
(2021)
Review
Green & Sustainable Science & Technology
Flavio Mattos, Joao Luiz Calmon
Summary: Since the publication of the Guidelines for Social Life Cycle Assessment (S-LCA) of Products by UNEP and SETAC in 2009, there has been an increase in research and publications using this tool to assess the social impacts of products and services. This article aims to survey current S-LCA models applied to MSWMS involving waste pickers and their organizations, in order to identify opportunities for research to expand the understanding and application of this tool. The analysis of selected articles reveals paths for improving the elements chosen for S-LCA models applied to MSWMS involving waste pickers.
Article
Agricultural Economics & Policy
Steffen Mink, Daria Loginova, Stefan Mann
Summary: The return of wolves in Swiss mountains has led to concerns over the closure of farms due to the damage caused to sheep and goat herds. This study examines the relationship between wolf attacks and the decline of Alpine summer farms. By analyzing farm structure data and monitoring data on wolf attacks from 2004 to 2021, the study finds that while occasional and infrequent wolf attacks have little impact on farming systems, a high number of attacks in a region leads to a faster decrease in grazing systems vulnerable to such attacks. However, systems with better herd protection tend to see an increase in areas with frequent wolf attacks.
JOURNAL OF AGRICULTURAL ECONOMICS
(2023)
Article
Agriculture, Multidisciplinary
Almudena Gomez-Ramos, Margarita Rico Gonzalez
Summary: Green Public Food Procurement (GPFP) is a valuable tool for achieving ecological transition objectives, and this study proposes a set of sustainability and health indicators to evaluate its performance. The results of two case studies in Spain show that certain factors, such as short marketing circuits and food sovereignty, contribute to improved economic sustainability and health performance. However, the implementation of renewable energies and the circular economy on a local scale is lacking, affecting environmental performance. These indicators can be used to drive sustainable food certification and change the current food model.
AGROECOLOGY AND SUSTAINABLE FOOD SYSTEMS
(2023)
Article
Economics
Marcela Parada-Contzen
Summary: This paper studies the design of investment policies in defined contribution retirement systems and estimates a dynamic system of correlated equations to fully model the individual's decision-making process. The results indicate that individuals opt for safer plans despite inertia and that mandating higher contributions does not significantly crowd out other behaviors.
B E JOURNAL OF ECONOMIC ANALYSIS & POLICY
(2022)
Review
Endocrinology & Metabolism
Alhanouf S. Al-Alsheikh, Shahd Alabdulkader, Alexander D. Miras, Anthony P. Goldstone
Summary: This systematic review collected studies on obesity interventions using positron emission tomography and single-photon emission computed tomography. From 604 publications, 22 met inclusion criteria, assessing bariatric surgery and dietary interventions with imaging techniques. The review summarizes the findings and correlations with clinical outcomes, eating behavior, and mechanistic mediators, but limitations in study designs hindered robust conclusions.
Article
Medical Laboratory Technology
Dalielah Jappie, Allen Rodgers, Neil Ravenscroft, Dawn Webber, Mayur Danny Gohel
Summary: This study found that urinary glycosaminoglycans (GAGs) have an inhibitory effect on calcium oxalate (CaOx) stone formation, with higher concentrations and stronger inhibition in the black population. This may contribute to the lower occurrence rate of kidney stones in black individuals.
CLINICA CHIMICA ACTA
(2022)
Article
Cell & Tissue Engineering
Tanira Giara Mello, Paulo Henrique Rosado-de-Castro, Raquel Maria Pereira Campos, Juliana Ferreira Vasques, William Simoes Rangel-Junior, Raphael Santos de Almeida Rezende de Mattos, Teresa Puig-Pijuan, Bernd Uwe Foerster, Bianca Gutfilen, Sergio Augusto Lopes Souza, Johannes Boltze, Fernando Fernandes Paiva, Rosalia Mendez-Otero, Pedro Moreno Pimentel-Coelho
STEM CELLS AND DEVELOPMENT
(2020)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Camila Edith Stachera Stasiak, Fabricius Rocha Cardoso, Sergio Altino de Almeida, Paulo Henrique Rosado-de-Castro
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2021)
Article
Multidisciplinary Sciences
Natalia dos Reis Ferreira, Carlos Miguel Machado Marto, Aleli Torres de Oliveira, Maria Joao Rodrigues, Marcos Fabio DosSantos
Summary: This study aims to develop a core outcome sets (COS) for clinical trials in intra-articular TMD and masticatory muscle disorders. By conducting systematic reviews and international Delphi surveys, the study aims to determine the core outcomes for TMD management interventions, reducing publication bias and enabling proper comparison of results.
Article
Neurosciences
Brenda de Souza Moura, Xiao-Su Hu, Marcos F. DosSantos, Alexandre F. DaSilva
Summary: This study aimed to investigate the analgesic effects of tDCS in head and neck cancer patients undergoing chemoradiation therapy and explore the underlying brain mechanisms. The study protocol included remote and in-clinic tDCS sessions, and brain imaging was performed using fNIRS and EEG. Preliminary results suggest that tDCS may reduce pain by modulating the connections between S1 and PFC.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2022)
Article
Medicine, Research & Experimental
Tanira Giara Mello, Paulo Henrique Rosado-de-Castro, Juliana Ferreira Vasques, Carolina Pinhao, Tayna Monteiro Santos, Renata Rodrigues de Lima, Bernd Uwe Foerster, Fernando Fernandes Paiva, Rosalia Mendez-Otero, Pedro Moreno Pimentel-Coelho
Summary: Intravenous injection of human umbilical cord-derived mesenchymal stromal cells (hUC-MSC) shows limited efficacy in the treatment of intracerebral hemorrhage (ICH), especially in severe cases. Hyperacute treatment with hUC-MSC does not significantly improve the survival rate, motor function, or residual hematoma volume in severe ICH. Further optimization of hUC-MSC-based therapies is needed.
Article
Cell Biology
Adriana Ximenes-da-Silva, Daniela Capra, Carolina Kaminski Sanz, Carmelita Bastos Mendes, Juliana de Mattos Coelho Aguiar, Vivaldo Moura-Neto, Marcos F. DosSantos
Summary: The inner ear, along with peripheral and central auditory pathways, plays a crucial role in hearing processing. Aquaporins (AQP) are integral membrane proteins that regulate water and ionic flow in the inner ear, and their expression changes are essential to auditory physiology and pathophysiological processes.
EUROPEAN JOURNAL OF CELL BIOLOGY
(2022)
Letter
Cardiac & Cardiovascular Systems
Remy Martins-Goncalves, Mariana M. Campos, Lohanna Palhinha, Isaclaudia G. Azevedo-Quintanilha, Mayara Abud Mendes, Jairo Ramos Temerozo, Julia Toledo-Mendes, Paulo H. Rosado-de-Castro, Fernando A. Bozza, Rosana Souza Rodrigues, Eugenio D. Hottz, Patricia T. Bozza
CIRCULATION RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Natalia R. Ferreira, Aleli T. Oliveira, Carolina Kaminski Sanz, Fabio R. Guedes, Maria Joao Rodrigues, Eduardo Grossmann, Marcos F. DosSantos
Summary: This study compared the efficacy of two protocols using high molecular weight hyaluronic acid (HA) intra-articular injection in patients with temporomandibular joint (TMJ) osteoarthritis, and evaluated the predictive role of subchondral bone changes and psychosocial factors in HA treatment. The results showed that both protocols were effective in reducing pain intensity and functional limitation caused by osteoarthritis, with the three-injection protocol showing more significant improvement in all outcomes.
CRANIO-THE JOURNAL OF CRANIOMANDIBULAR & SLEEP PRACTICE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Glaucia Marques Dias, Eduardo Grossmann, Antonio Carlos Pires Carvalho, Karina Lopes Devito, Marcos Fabio dos Santos, Luciano Ambrosio Ferreira
Summary: This study investigated the changes in MRI of TMJ with anterior displacement disk without reduction (DDwoR) and its correlation to clinical symptoms. The results showed that TMJ degeneration, effusion, disc's shape and position were associated with pain's intensity and chronicity.
CRANIO-THE JOURNAL OF CRANIOMANDIBULAR & SLEEP PRACTICE
(2023)
Review
Neurosciences
Andre Quincozes-Santos, Larissa Daniele Bobermin, Naithan Ludian Fernandes Costa, Natalie K. Thomaz, Romulo Rodrigo de Souza Almeida, Walter O. Beys-da-Silva, Lucelia Santi, Rafael L. Rosa, Daniela Capra, Juliana M. Coelho-Aguiar, Marcos Fabio DosSantos, Manoela Heringer, Elizabeth O. Cirne-Lima, Jorge Almeida Guimaraes, Lavinia Schuler-Faccini, Carlos-Alberto Goncalves, Vivaldo Moura-Neto, Diogo Onofre Souza
Summary: Zika virus infects glial cells in both the central and peripheral nervous systems, leading to neurological complications and potential neurodevelopmental disorders. Understanding the changes in glial cell functions, including inflammatory response, oxidative stress, mitochondrial dysfunction, calcium and glutamate homeostasis, neural metabolism, and neuron-glia communication, may contribute to the development of preventive and therapeutic strategies against Zika virus-induced neurodegeneration.
Article
Biochemistry & Molecular Biology
Carla Pires Verissimo, Lionete Gall Acosta Filha, Fabio Jorge Moreira da Silva, Harrison Westgarth, Juliana De Mattos Coelho Aguiar, Bruno Pontes, Vivaldo Moura-Neto, Parisa Gazerani, Marcos F. DosSantos
Summary: Multiple studies have shown that glial cells, including both central and peripheral glial cells, are involved in pain pathophysiology. However, the study of peripheral glial cells, particularly satellite glial cells (SGCs), is challenging and controversial in vitro. In this study, the researchers successfully developed a research protocol to establish primary mixed neuronal-glia cell cultures obtained from neonate mice's trigeminal ganglion cells (TGCs). Through morphological and immunocytochemical analysis, they found evidence of plasticity in cultured SGCs and their relationship with neurons.
CURRENT ISSUES IN MOLECULAR BIOLOGY
(2022)
Review
Clinical Neurology
Natalia dos Reis Ferreira, Carolina Kaminski Sanz, Aline Raybolt, Claudia Maria Pereira, Marcos Fabio DosSantos
Summary: The temporomandibular joint (TMD) is an important component of complex biological mechanisms such as the immune system and inflammatory processes. Hyaluronic acid (HA) plays a crucial role in injury and healing, while its degradation product, low molecular weight HA, may act as damage-associated molecular patterns (DAMPs) to trigger immune responses.
FRONTIERS IN PAIN RESEARCH
(2022)
Article
Medicine, General & Internal
Rafael Rossini, Eduardo Grossmann, Rodrigo L. Poluha, Enio T. Setogutti, Marcos Fabio Dos Santos
Summary: Arthrocentesis combined with hyaluronic acid injection significantly improves pain perception and maximum mouth opening in patients with unilateral disc displacement without reduction (DDwoR) in the mid-term follow-up period.
Review
Biochemistry & Molecular Biology
Luiz Henrique Medeiros Geraldo, Tania Cristina Leite de Sampaio Spohr, Rackele Ferreira do Amaral, Anna Carolina Carvalho da Fonseca, Celina Garcia, Fabio de Almeida Mendes, Catarina Freitas, Marcos Fabio dosSantos, Flavia Regina Souza Lima
Summary: Lysophosphatidic acid (LPA) is a versatile bioactive phospholipid that can signal through specific receptors to have diverse effects in central nervous system development and angiogenesis, as well as acting as a potent mediator in neuropathic pain, neurodegenerative diseases, and cancer progression. Understanding the production and signaling mechanisms of LPA is crucial for comprehending its biological functions in the central nervous system in both health and disease states.
SIGNAL TRANSDUCTION AND TARGETED THERAPY
(2021)
