Role of androgen receptor splice variants, their clinical relevance and treatment options
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Role of androgen receptor splice variants, their clinical relevance and treatment options
Authors
Keywords
Androgen receptor, Splice variant, AR-V, Clinical relevance
Journal
WORLD JOURNAL OF UROLOGY
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2019-01-19
DOI
10.1007/s00345-018-02619-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Bedeutung der Androgenrezeptor-Spleißvariante AR-V7 für Prognose und Therapie des fortgeschrittenen Prostatakarzinoms
- (2018) P. Thelen et al. AKTUELLE UROLOGIE
- Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases
- (2018) Heini M. L. Kallio et al. BRITISH JOURNAL OF CANCER
- Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer
- (2018) Michael A. Moses et al. CANCER RESEARCH
- Bipolar androgen therapy in men with metastatic castration-resistant prostate cancer after progression on enzalutamide: an open-label, phase 2, multicohort study
- (2018) Benjamin A Teply et al. LANCET ONCOLOGY
- H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers
- (2018) Michael Seiler et al. NATURE MEDICINE
- Overexpression of nuclear AR-V7 protein in primary prostate cancer is an independent negative prognostic marker in men with high-risk disease receiving adjuvant therapy
- (2018) Xin Chen et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer
- (2018) Ling Cai et al. MOLECULAR CELL
- Androgen receptor isoforms expression in benign prostatic hyperplasia and primary prostate cancer
- (2018) Ana Caroline Hillebrand et al. PLoS One
- Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer
- (2018) Chengfei Liu et al. Nature Communications
- Bipolar Androgen Therapy: A Paradoxical Approach for the Treatment of Castration-resistant Prostate Cancer
- (2017) Michael T. Schweizer et al. EUROPEAN UROLOGY
- Comprehensive Profiling of the Androgen Receptor in Liquid Biopsies from Castration-resistant Prostate Cancer Reveals Novel Intra-AR Structural Variation and Splice Variant Expression Patterns
- (2017) Bram De Laere et al. EUROPEAN UROLOGY
- Expression of AR-V7 in Circulating Tumour Cells Does Not Preclude Response to Next Generation Androgen Deprivation Therapy in Patients with Castration Resistant Prostate Cancer
- (2017) Christof Bernemann et al. EUROPEAN UROLOGY
- EAU-ESTRO-SIOG Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent
- (2017) Nicolas Mottet et al. EUROPEAN UROLOGY
- Clinical Significance of Androgen Receptor Splice Variant-7 mRNA Detection in Circulating Tumor Cells of Men With Metastatic Castration-Resistant Prostate Cancer Treated With First- and Second-Line Abiraterone and Enzalutamide
- (2017) Emmanuel S. Antonarakis et al. JOURNAL OF CLINICAL ONCOLOGY
- C-terminally truncated constitutively active androgen receptor variants and their biologic and clinical significance in castration-resistant prostate cancer
- (2017) Anca Azoitei et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Ipatasertib plus paclitaxel versus placebo plus paclitaxel as first-line therapy for metastatic triple-negative breast cancer (LOTUS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
- (2017) Sung-Bae Kim et al. LANCET ONCOLOGY
- Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells
- (2016) R. Ferraldeschi et al. CANCER RESEARCH
- The importance of non-nuclear AR signaling in prostate cancer progression and therapeutic resistance
- (2016) Jelani C. Zarif et al. CELLULAR SIGNALLING
- Testosterone in Androgen Receptor Signaling and DNA Repair: Enemy or Frenemy?
- (2016) M. L. K. Chua et al. CLINICAL CANCER RESEARCH
- The PI3K AKT pathway in the pathogenesis of prostate cancer
- (2016) Xiaofei Wen Frontiers in Bioscience-Landmark
- Histone deacetylases function as novel potential therapeutic targets for cancer
- (2016) Hui Zhang et al. HEPATOLOGY RESEARCH
- Galeterone for the treatment of advanced prostate cancer: the evidence to date
- (2016) Emmanuel Antonarakis et al. Drug Design Development and Therapy
- Critical role of androgen receptor level in prostate cancer cell resistance to new generation antiandrogen enzalutamide
- (2016) Julia Hoefer et al. Oncotarget
- Association of AR-V7 on Circulating Tumor Cells as a Treatment-Specific Biomarker With Outcomes and Survival in Castration-Resistant Prostate Cancer
- (2016) Howard I. Scher et al. JAMA Oncology
- Efficacy of Cabazitaxel in Castration-resistant Prostate Cancer Is Independent of the Presence of AR-V7 in Circulating Tumor Cells
- (2015) Wendy Onstenk et al. EUROPEAN UROLOGY
- Role of BioResponse 3,3′-Diindolylmethane in the Treatment of Human Prostate Cancer: Clinical Experience
- (2015) Yiwei Li et al. MEDICAL PRINCIPLES AND PRACTICE
- Therapy escape mechanisms in the malignant prostate
- (2015) Frédéric R. Santer et al. SEMINARS IN CANCER BIOLOGY
- Expression of androgen receptor splice variants in clinical breast cancers
- (2015) Theresa E. Hickey et al. Oncotarget
- Androgen Receptor Splice Variant 7 and Efficacy of Taxane Chemotherapy in Patients With Metastatic Castration-Resistant Prostate Cancer
- (2015) Emmanuel S. Antonarakis et al. JAMA Oncology
- Scientific Rationale Supporting the Clinical Development Strategy for the Investigational Aurora A Kinase Inhibitor Alisertib in Cancer
- (2015) Huifeng Niu et al. Frontiers in Oncology
- Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors
- (2015) Joanna L Gillis et al. Oncotarget
- Niclosamide Inhibits Androgen Receptor Variants Expression and Overcomes Enzalutamide Resistance in Castration-Resistant Prostate Cancer
- (2014) C. Liu et al. CLINICAL CANCER RESEARCH
- Androgen receptor and its splice variant, AR-V7, differentially regulate FOXA1 sensitive genes in LNCaP prostate cancer cells
- (2014) William C. Krause et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
- (2014) Jacques Ferlay et al. INTERNATIONAL JOURNAL OF CANCER
- Mechanisms of the androgen receptor splicing in prostate cancer cells
- (2013) L L Liu et al. ONCOGENE
- Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer
- (2012) R. Hu et al. CANCER RESEARCH
- Androgen Receptor Splice Variants Mediate Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cell Lines
- (2012) Y. Li et al. CANCER RESEARCH
- Stepwise androgen receptor dimerization
- (2012) M. E. van Royen et al. JOURNAL OF CELL SCIENCE
- EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent
- (2012) K. Xu et al. SCIENCE
- AR-Q640X, a model to study the effects of constitutively active C-terminally truncated AR variants in prostate cancer cells
- (2012) Wolfgang Streicher et al. WORLD JOURNAL OF UROLOGY
- Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1
- (2011) Changmeng Cai et al. CANCER CELL
- Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants
- (2011) Elahe A. Mostaghel et al. CLINICAL CANCER RESEARCH
- Androgen Receptor Cofactors in Prostate Cancer: Potential Therapeutic Targets of Castration-Resistant Prostate Cancer
- (2011) Masaki Shiota et al. CURRENT CANCER DRUG TARGETS
- Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer
- (2011) Biswajyoti Sahu et al. EMBO JOURNAL
- Clinical and Biochemical Consequences of CYP17A1 Inhibition with Abiraterone Given with and without Exogenous Glucocorticoids in Castrate Men with Advanced Prostate Cancer
- (2011) Gerhardt Attard et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Abiraterone and Increased Survival in Metastatic Prostate Cancer
- (2011) Johann S. de Bono et al. NEW ENGLAND JOURNAL OF MEDICINE
- Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival
- (2011) Emma Hörnberg et al. PLoS One
- Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1–2 study
- (2010) Howard I Scher et al. LANCET
- Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
- (2009) C. Tran et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search