Concept of histone deacetylases in cancer: Reflections on esophageal carcinogenesis and treatment

Silence of HDAC6 suppressed esophageal squamous cell carcinoma proliferation and migration by disrupting chaperone function of HSP90

(2018) Hua Tao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Depletion of HDAC1, 7 and 8 by Histone Deacetylase Inhibition Confers Elimination of Pancreatic Cancer Stem Cells in Combination with Gemcitabine

(2018) Mao-Hua Cai et al.   Scientific Reports

Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner

(2017) Vivek Kumar Mishra et al.   NUCLEIC ACIDS RESEARCH

A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis

(2017) Bing-yan Zhu et al.   Oncotarget

Overexpressed HDAC4 is associated with poor survival and promotes tumor progression in esophageal carcinoma

(2016) Li-Si Zeng et al.   Aging-US

Suppression of Tumor Growth and Muscle Wasting in a Transgenic Mouse Model of Pancreatic Cancer by the Novel Histone Deacetylase Inhibitor AR-42

(2016) Sally E. Henderson et al.   NEOPLASIA

Impact of Histone Deacetylase Inhibitors on microRNA Expression and Cancer Therapy: A Review

(2015) Saira R. Ali et al.   DRUG DEVELOPMENT RESEARCH

Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine

(2015) Theresa D Ahrens et al.   Epigenetics

Inhibitory effects of valproic acid in DNA double-strand break repair after irradiation in esophageal squamous carcinoma cells

(2015) NAOKI MAKITA et al.   ONCOLOGY REPORTS

Esophageal cancer: Risk factors, screening and endoscopic treatment in Western and Eastern countries

(2015) María José Domper Arnal   WORLD JOURNAL OF GASTROENTEROLOGY

HDAC4 as a potential therapeutic target in neurodegenerative diseases: a summary of recent achievements

(2015) Michal Mielcarek et al.   Frontiers in Cellular Neuroscience

Targeting Histone Deacetylases for Cancer Therapy: From Molecular Mechanisms to Clinical Implications

(2014) Zhiming Li et al.   International Journal of Biological Sciences

Upregulation of KLF4 by methylseleninic acid in human esophageal squamous cell carcinoma cells: Modification of histone H3 acetylation through HAT/HDAC interplay

(2014) Chenfei Hu et al.   MOLECULAR CARCINOGENESIS

Immunohistochemical analysis on potential new molecular targets for esophageal cancer

(2013) J. Maurer et al.   DISEASES OF THE ESOPHAGUS

Oesophageal carcinoma

(2013) Arjun Pennathur et al.   LANCET

Growth inhibition of pancreatic cancer cells by histone deacetylase inhibitor belinostat through suppression of multiple pathways including HIF, NFkB, and mTOR signaling in vitro and in vivo

(2013) Wenwen Chien et al.   MOLECULAR CARCINOGENESIS

Histone deacetylase inhibitors and pancreatic cancer: Are there any promising clinical trials?

(2013) Ioannis Koutsounas   WORLD JOURNAL OF GASTROENTEROLOGY

Effects of DNA methyltransferase 1 inhibition on esophageal squamous cell carcinoma

(2011) Shu-Lei Zhao et al.   DISEASES OF THE ESOPHAGUS

Expression of class I histone deacetylases (HDAC1 and HDAC2) in oesophageal adenocarcinomas: an immunohistochemical study

(2010) R. Langer et al.   JOURNAL OF CLINICAL PATHOLOGY

An unusual tumor of the esophagus

(2010) George Rakovich et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair

(2010) J.- H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin

(2009) X Wu et al.   BRITISH JOURNAL OF CANCER