Immunosuppressives and biologics during pregnancy and lactation

Long-Term Safety of In Utero Exposure to Anti-TNFα Drugs for the Treatment of Inflammatory Bowel Disease: Results from the Multicenter European TEDDY Study

(2018) M Chaparro et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Use of Biologic Therapy by Pregnant Women With Inflammatory Bowel Disease Does Not Affect Infant Response to Vaccines

(2018) Dawn B. Beaulieu et al.   Clinical Gastroenterology and Hepatology

Vedolizumab Concentrations in the Breast Milk of Nursing Mothers With Inflammatory Bowel Disease

(2018) Mette Julsgaard et al.   GASTROENTEROLOGY

Pregnancy Outcomes after Exposure to Certolizumab Pegol: Updated Results from a Pharmacovigilance Safety Database

(2018) Megan E. B. Clowse et al.   Arthritis & Rheumatology

Drug Safety and Risk of Adverse Outcomes for Pregnant Patients With Inflammatory Bowel Disease

(2017) Uma Mahadevan et al.   GASTROENTEROLOGY

Vedolizumab safety in pregnancy and newborn outcomes

(2017) Mette Julsgaard et al.   GUT

The Effect of Disease Activity on Birth Outcomes in a Nationwide Cohort of Women with Moderate to Severe Inflammatory Bowel Disease

(2017) Heidi Kammerlander et al.   INFLAMMATORY BOWEL DISEASES

Systemic medications used in treatment of common dermatological conditions: Safety profile with respect to pregnancy, breast feeding and content in seminal fluid

(2017) SM Brown et al.   JOURNAL OF DERMATOLOGICAL TREATMENT

Pregnancy and infant outcomes including major congenital malformations among women with chronic inflammatory arthritis or psoriasis, with and without etanercept use

(2017) Wendy J. Carman et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

International multi-centre study of pregnancy outcomes with interleukin-1 inhibitors

(2017) Taryn Youngstein et al.   RHEUMATOLOGY

The use of biologics in pregnant patients with rheumatic disease

(2017) Monika Østensen   Expert Review of Clinical Pharmacology

The EULAR points to consider for use of antirheumatic drugs before pregnancy, and during pregnancy and lactation

(2016) Carina Götestam Skorpen et al.   ANNALS OF THE RHEUMATIC DISEASES

EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome

(2016) L Andreoli et al.   ANNALS OF THE RHEUMATIC DISEASES

Preconception Care Reduces Relapse of Inflammatory Bowel Disease During Pregnancy

(2016) Alison de Lima et al.   Clinical Gastroenterology and Hepatology

Pregnancy Outcomes in the Tofacitinib Safety Databases for Rheumatoid Arthritis and Psoriasis

(2016) Megan E. B. Clowse et al.   DRUG SAFETY

Concentrations of Adalimumab and Infliximab in Mothers and Newborns, and Effects on Infection

(2016) Mette Julsgaard et al.   GASTROENTEROLOGY

The Toronto Consensus Statements for the Management of Inflammatory Bowel Disease in Pregnancy

(2016) Geoffrey C. Nguyen et al.   GASTROENTEROLOGY

Certolizumab treatment during late pregnancy in patients with rheumatic diseases: Low drug levels in cord blood but possible risk for maternal infections. A case series of 13 patients

(2016) Frauke Förger et al.   JOINT BONE SPINE

Anti-Tumour Necrosis Factor α Therapies and Inflammatory Bowel Disease Pregnancy Outcomes: A Meta-analysis

(2016) Zaid Shihab et al.   Journal of Crohns & Colitis

Risk of Serious Infections in Patients with Psoriasis on Biologic Therapies: A Systematic Review and Meta-Analysis

(2016) Zenas Z.N. Yiu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding—Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids: Table 1

(2016) Julia Flint et al.   RHEUMATOLOGY

Tocilizumab use in pregnancy: Analysis of a global safety database including data from clinical trials and post-marketing data

(2016) Maria Hoeltzenbein et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Favorable pregnancy outcome in a patient with systemic lupus erythematosus treated with belimumab: A confirmation report

(2016) Giacomo Emmi et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Pregnancy outcome after TNF-α inhibitor therapy during the first trimester: a prospective multicentre cohort study

(2015) Corinna Weber-Schoendorfer et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Pregnancy during Ustekinumab Treatment for Severe Psoriasis

(2015) Katiucia Rocha et al.   DERMATOLOGY

Su1091 Pregnancy Outcome in Women Treated With Adalimumab for the Treatment of Rheumatoid Arthritis: An Update on the OTIS Autoimmune Diseases in Pregnancy Project

(2015) Christina D. Chambers et al.   GASTROENTEROLOGY

Tailored anti-TNF therapy during pregnancy in patients with IBD: maternal and fetal safety

(2015) A de Lima et al.   GUT

Treating Inflammatory Bowel Disease in Pregnancy: The Issues We Face Today

(2015) Oriana M. Damas et al.   Journal of Crohns & Colitis

Pregnancy outcomes following exposure to abatacept during pregnancy

(2015) Monica Kumar et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

865 PIANO: A 1000 Patient Prospective Registry of Pregnancy Outcomes in Women With IBD Exposed to Immunomodulators and Biologic Therapy

(2015) Uma Mahadevan et al.   GASTROENTEROLOGY

Maternal and foetal adverse events with tumour necrosis factor-alpha inhibitors in inflammatory bowel disease

(2014) P. Deepak et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

OP0041 Pregnancy Outcomes for Systemic Lupus Erythematosus (SLE) Subjects with Conception during Belimumab Intravenous (IV) and Subcutaneous (SC) Placebo-Controlled Clinical Trials and Long Term Extension Trials

(2014) M. Powell et al.   ANNALS OF THE RHEUMATIC DISEASES

Pregnancy outcomes of two patients exposed to ustekinumab in the first trimester

(2014) Claire Sheeran et al.   AUSTRALASIAN JOURNAL OF DERMATOLOGY

The use of biologic therapy in pregnancy

(2014) Benjamin Hassid et al.   CURRENT OPINION IN RHEUMATOLOGY

Anti-TNFα Therapies Are Safe During Pregnancy in Women with Inflammatory Bowel Disease

(2014) Neeraj Narula et al.   INFLAMMATORY BOWEL DISEASES

Birth Outcomes in Women with Inflammatory Bowel Disease

(2014) Gabriella Bröms et al.   INFLAMMATORY BOWEL DISEASES

Inadvertent pregnancy during ustekinumab therapy in a patient with plaque psoriasis and impetigo herpetiformis

(2014) A. Alsenaid et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Anti-TNF-  Therapy May Cause Neonatal Neutropenia

(2014) T. Guiddir et al.   PEDIATRICS

Pregnancy Outcomes in Liver and Cardiothoracic Transplant Recipients: A UK National Cohort Study

(2014) Olaa Mohamed-Ahmed et al.   PLoS One

Self-reported adherence to medical treatment, breastfeeding behaviour, and disease activity during the postpartum period in women with Crohn’s disease

(2014) Mette Julsgaard et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Use of belimumab throughout pregnancy to treat active systemic lupus erythematosus—A case report

(2014) Abhijeet Danve et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Preconception care: screening and management of chronic disease and promoting psychological health

(2014) Zohra S Lassi et al.   Reproductive Health

Brief Report: Anakinra Use During Pregnancy in Patients With Cryopyrin-Associated Periodic Syndromes

(2014) Zenas Chang et al.   Arthritis & Rheumatology

Pregnancy Outcome After Methotrexate Treatment for Rheumatic Disease Prior to or During Early Pregnancy: A Prospective Multicenter Cohort Study

(2014) Corinna Weber-Schoendorfer et al.   Arthritis & Rheumatology

Long-term follow-up of children exposed intrauterine to maternal thiopurine therapy during pregnancy in females with inflammatory bowel disease

(2013) T. G. J. de Meij et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Exposure to abatacept or rituximab in the first trimester of pregnancy in three women with autoimmune diseases

(2013) Mario Ojeda-Uribe et al.   CLINICAL RHEUMATOLOGY

Intrauterine exposure and pharmacology of conventional thiopurine therapy in pregnant patients with inflammatory bowel disease

(2013) Bindia Jharap et al.   GUT

Methotrexate embryopathy after exposure to low weekly doses in early pregnancy

(2013) María Cecilia Martín et al.   REPRODUCTIVE TOXICOLOGY

Pregnancy outcome following gestational exposure to TNF-alpha-inhibitors: A prospective, comparative, observational study

(2013) Orna Diav-Citrin et al.   REPRODUCTIVE TOXICOLOGY

Teratogenicity of mycophenolate confirmed in a prospective study of the European Network of Teratology Information Services

(2012) Maria Hoeltzenbein et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Pregnancy outcome in women exposed to leflunomide before or during pregnancy

(2012) M. Cassina et al.   ARTHRITIS AND RHEUMATISM

Teratogen update: Methotrexate

(2012) Sara C. Hyoun et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

The Effects of Interleukin-6 Signal Blockade on Fertility, Embryo-fetal Development, and Immunization In vivo

(2012) Takayuki Sakurai et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Placental Transfer of Anti–Tumor Necrosis Factor Agents in Pregnant Patients With Inflammatory Bowel Disease

(2012) Uma Mahadevan et al.   Clinical Gastroenterology and Hepatology

Systematic Review and Meta-analysis on the Effects of Thiopurines on Birth Outcomes from Female and Male Patients with Inflammatory Bowel Disease

(2012) Mona Akbari et al.   INFLAMMATORY BOWEL DISEASES

Abatacept therapy and safety management

(2012) Thao Pham et al.   JOINT BONE SPINE

Inflammatory bowel disease and pregnancy: Lack of knowledge is associated with negative views

(2012) Christian P. Selinger et al.   Journal of Crohns & Colitis

The fetal safety of thiopurines for the treatment of inflammatory bowel disease in pregnancy

(2012) J. R. Hutson et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY

High intra-uterine exposure to infliximab following maternal anti-TNF treatment during pregnancy

(2011) Z. Zelinkova et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Anti-TNF therapies and pregnancy: outcome of 130 pregnancies in the British Society for Rheumatology Biologics Register

(2011) S. M. M. Verstappen et al.   ANNALS OF THE RHEUMATIC DISEASES

Long-term safety experience of ustekinumab in patients with moderate-to-severe psoriasis (Part I of II): Results from analyses of general safety parameters from pooled Phase 2 and 3 clinical trials

(2011) Mark Lebwohl et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Perinatal Outcomes of a Pregnancy Complicated by Cancer, Including Neonatal Follow-Up After in Utero Exposure to Chemotherapy

(2010) Elyce Cardonick et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD With the European Crohn's and Colitis Organisation: Pregnancy and Pediatrics

(2010) Uma Mahadevan et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Birth outcomes in women who have taken leflunomide during pregnancy

(2010) Christina D. Chambers et al.   ARTHRITIS AND RHEUMATISM

Development in the cynomolgus macaque following administration of ustekinumab, a human anti-il-12/23p40 monoclonal antibody, during pregnancy and lactation

(2010) Pauline L. Martin et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Pregnancy outcomes after maternal exposure to rituximab

(2010) E. F. Chakravarty et al.   BLOOD

Altered drug metabolism during pregnancy: hormonal regulation of drug-metabolizing enzymes

(2010) Hyunyoung Jeong   Expert Opinion on Drug Metabolism & Toxicology

Self-reported adherence to medical treatment prior to and during pregnancy among women with ulcerative colitis

(2010) Mette Julsgaard et al.   INFLAMMATORY BOWEL DISEASES

Case Report: Fatal case of disseminated BCG infection in an infant born to a mother taking infliximab for Crohn's Disease

(2010) Kuldeep Cheent et al.   Journal of Crohns & Colitis

Long-term follow-up of babies exposed to azathioprine in utero and via breastfeeding

(2010) Sieglinde Angelberger et al.   Journal of Crohns & Colitis

Etanercept concentrations in maternal serum, umbilical cord serum, breast milk and child serum during breastfeeding

(2010) B. G. Berthelsen et al.   RHEUMATOLOGY

Etanercept during pregnancy and lactation in a patient with rheumatoid arthritis: drug levels in maternal serum, cord blood, breast milk and the infant's serum

(2009) A Murashima et al.   ANNALS OF THE RHEUMATIC DISEASES

A patient's wish: anakinra in pregnancy

(2009) C T Berger et al.   ANNALS OF THE RHEUMATIC DISEASES

Reproductive wish represents an important factor influencing therapeutic strategy in inflammatory bowel diseases

(2009) Zuzana Zelinkova et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Azathioprine treatment during lactation

(2008) L. A. CHRISTENSEN et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Relapses of Inflammatory Bowel Disease During Pregnancy: In-Hospital Management and Birth Outcomes

(2008) Deepa Reddy et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Rituximab Administration in Third Trimester of Pregnancy Suppresses Neonatal B-Cell Development

(2008) D. T. Klink et al.   Clinical & Developmental Immunology

Fear and fertility in inflammatory bowel disease: A mismatch of perception and reality affects family planning decisions

(2008) Réme Mountifield et al.   INFLAMMATORY BOWEL DISEASES

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

(2008) Craig L Leonardi et al.   LANCET

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)

(2008) Kim A Papp et al.   LANCET