Increasing FIM2/3 antigen-content improves efficacy of Bordetella pertussis vaccines in mice in vivo without altering vaccine-induced human reactogenicity biomarkers in vitro

Title
Increasing FIM2/3 antigen-content improves efficacy of Bordetella pertussis vaccines in mice in vivo without altering vaccine-induced human reactogenicity biomarkers in vitro
Authors
Keywords
Bordetella pertussis, Fimbriae, Pertactin, Acellular pertussis vaccines, Whole cell pertussis vaccines, Reactogenicity
Journal
VACCINE
Volume 37, Issue 1, Pages 80-89
Publisher
Elsevier BV
Online
2018-11-24
DOI
10.1016/j.vaccine.2018.11.028

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