Challenges recruiting to a proof-of-concept pharmaceutical trial for a rare disease: the trigeminal neuralgia experience

Safety and efficacy of a Nav1.7 selective sodium channel blocker in patients with trigeminal neuralgia: a double-blind, placebo-controlled, randomised withdrawal phase 2a trial

(2017) Joanna M Zakrzewska et al.   LANCET NEUROLOGY

Evaluating the impact of trigeminal neuralgia

(2017) Joanna M. Zakrzewska et al.   PAIN

Participation of the elderly, women, and minorities in pivotal trials supporting 2011–2013 U.S. Food and Drug Administration approvals

(2016) Nicholas S. Downing et al.   Trials

Innovative research methods for studying treatments for rare diseases: methodological review

(2014) J. J. Gagne et al.   BMJ-British Medical Journal

The International Classification of Headache Disorders, 3rd edition (beta version)

(2013)   CEPHALALGIA

Clinical Trials in Rare Disease

(2013) Erika F. Augustine et al.   JOURNAL OF CHILD NEUROLOGY

Novel design for a phase IIa placebo-controlled, double-blind randomized withdrawal study to evaluate the safety and efficacy of CNV1014802 in patients with trigeminal neuralgia

(2013) Joanna M Zakrzewska et al.   Trials

Study design attributes influenced patients' willingness to participate in clinical research: a randomized vignette-based study

(2010) Thomas Agoritsas et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Incidence of facial pain in the general population

(2009) Joseph S.H.A. Koopman et al.   PAIN

Incidence rates and treatment of neuropathic pain conditions in the general population☆

(2008) Jeanne P. Dieleman et al.   PAIN