Article
Geriatrics & Gerontology
Kota Yamauchi, Kenichi Kumagae, Kei Goto, Eisei Harayama, Shota Tanaka, Risa Hagiwara, Yoshiko Uchida, Sota Kuroyama, Yasuhiro Koyanagi, Shuji Arakawa
Summary: The study found a close relationship between ambulation ability at discharge from an acute hospital and the risk of pneumonia and death in stroke patients 1 year after the stroke episode. The higher the degree of ambulatory impairment, the higher the risk of pneumonia and death for patients.
GERIATRICS & GERONTOLOGY INTERNATIONAL
(2022)
Article
Neurosciences
Susanne Palmcrantz, Anneli Wall, Katarina Skough Vreede, Pavel Lindberg, Anna Danielsson, Katharina S. Sunnerhagen, Charlotte K. Hager, Jorgen Borg
Summary: This study examined the impact of training with an electromechanically assisted gait training (EAGT) system, specifically the Hybrid Assistive Limb(R) (HAL), integrated with conventional rehabilitation on long-term improvements in individuals post-stroke. The findings suggest that intensive conventional gait training induced significant improvements while the integration of treadmill-based EAGT did not provide additional value in this study sample.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Health Care Sciences & Services
Jong Taek Lee, Eunhee Park, Tae-Du Jung
Summary: This study developed a framework for classifying dependence in ambulation using a 3D convolutional neural network on video data recorded by smartphones during inpatient rehabilitation therapy for stroke patients. The proposed framework can alert clinicians or caregivers when stroke patients with dependent ambulation move alone without assistance, facilitating the design of individualized rehabilitation strategies.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Rehabilitation
Caroline M. Stretton, Suzie Mudge, Nicola M. Kayes, Kathryn M. McPherson
Summary: Understanding the personal experiences of stroke survivors in real-world walking is crucial for tailoring interventions to meet their specific needs. This study found that real-world walking provided opportunities for freedom, progress, and hope for recovery, but also presented challenges and negative emotions. Stroke survivors used everyday routines, planning skills, and confidence-building experiences to overcome obstacles and achieve their walking goals. They also relied on social resources and connections. Successful progress in real-world walking enhanced confidence, hope, and psychological well-being.
DISABILITY AND REHABILITATION
(2022)
Article
Clinical Neurology
Mercedes Paniagua-Monrobel, Isabel Escobio-Prieto, Eleonora Magni, Alejandro Galan-Mercant, David Lucena-Anton, Elena Pinero-Pinto, Carlos Luque-Moreno
Summary: Physical therapy is essential for functional recovery after a stroke. This study analyzed clinical history data of stroke patients who received physical therapy to identify a preferential patient profile for early treatment. The results indicate that younger patients with hemorrhagic stroke, particularly on the left side or bilateral, are more suitable for early physical therapy.
FRONTIERS IN NEUROLOGY
(2023)
Article
Medicine, General & Internal
Masatsugu Okamura, Masaaki Konishi, Akiko Sagara, Yasuo Shimizu, Takeshi Nakamura
Summary: Early mobilization was found to be associated with favorable discharge disposition and functional status in patients with subarachnoid hemorrhage in this retrospective study, suggesting the potential benefits of early rehabilitation in this patient population.
Article
Clinical Neurology
Saleh M. Aloraini
Summary: This study investigated the effectiveness of constraint-induced movement therapy for the lower extremity (CIMT-LE) in improving balance and ambulation among stroke survivors. The results showed that the CIMT-LE program led to significant clinical improvements in lower extremity motor recovery, postural balance, and gait speed. These improvements were retained even three months after the conclusion of the program.
NEUROREHABILITATION
(2022)
Article
Medicine, General & Internal
Daham Kim, Jae-Hyung Kim, Si-Woon Park, Hyung-Wook Han, Sang Joon An, Yeong In Kim, Hyo Jin Ju, YoonHee Choi, Doo Young Kim
Summary: This retrospective study investigated the usefulness of videofluoroscopic swallowing study (VFSS) in predicting long-term all-cause mortality in subacute stroke patients. The study found that the recommended dietary type and VFSS parameters, including fluid penetration and aspiration, were significant risk factors for mortality. Therefore, it is important to classify the degree of dysphagia using VFSS and determine appropriate dietary and rehabilitation interventions for subacute stroke patients.
Article
Engineering, Biomedical
Ling-Fung Yeung, Cathy C. Y. Lau, Charles W. K. Lai, Yannie O. Y. Soo, Man-Lok Chan, Raymond K. Y. Tong
Summary: This study found that robot-assisted stair training can be more effective in improving gait recovery and promoting independence than conventional training. Patients using SCAR robot showed significant improvement in gait recovery, while patients using PAAR robot demonstrated greater increase in walking speed.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2021)
Editorial Material
Clinical Neurology
Farooq Azam Rathore, Shaikh Nabi Bukhsh Nazir
Summary: This study summarized the evidence on the effects of antiepileptic drugs (AEDs) on the prevention of post-stroke seizures. The findings showed that AEDs were not effective in preventing seizures after a stroke and did not affect the mortality rate. However, due to the low certainty of the evidence, it is still unclear whether routine use of AEDs is necessary for the prevention of post-stroke seizures.
NEUROREHABILITATION
(2023)
Article
Rehabilitation
Merel-Anne Brehm, Hilde E. Ploeger, Frans Nollet
Summary: The simplified 3-level self-reported ambulation classification by Perry is a clinically meaningful tool for polio survivors, as it consistently corresponds to differences in objective and self-reported indicators of physical mobility. Categories of household walkers, limited community walkers, and full community walkers showed significant differences in walked distance, energy cost, SF36-PF, and FSS scores, with walked distance and SF36-PF score significantly associated with functional ambulation level.
ANNALS OF PHYSICAL AND REHABILITATION MEDICINE
(2021)
Article
Clinical Neurology
Shengde Li, Shiyuan Fang, Dingding Zhang, Yixiu Lu, Longde Wang, Bin Peng
Summary: This study aimed to investigate whether sequential therapy by rehabilitation could reduce the in-hospital mortality of patients treated with reperfusion therapy. The study found that among patients with ischemic stroke treated with intravenous thrombolysis or endovascular therapy, sequential therapy by rehabilitation was associated with lower all-cause in-hospital mortality.
FRONTIERS IN NEUROLOGY
(2022)
Article
Rehabilitation
David A. Snowdon, Vatthana Sounthakith, Jessica Kolic, Sarah Brooks, Sinead Scanlon, Nicholas F. Taylor
Summary: The study found that only about one-third of inpatients discharged home from a publicly funded rehabilitation center met the criteria for community ambulation, with walking 315 meters continuously and ascending/descending steps being the least commonly met criteria. Female patients, those with a high comorbidity index, or a traumatic orthopaedic diagnosis were less likely to meet all criteria, while patients with a higher admission functional independence walk item score or higher ambulatory self-confidence were more likely to meet all criteria.
DISABILITY AND REHABILITATION
(2021)
Article
Medicine, General & Internal
Dong-Yup Yoo, Jung-Kyu Choi, Chang-Yoon Baek, Jung-Bin Shin
Summary: This study aimed to investigate the impact of intensive rehabilitation on the long-term prognosis of patients with stroke. Through analyzing data from the National Health Insurance Service database, it was found that stroke patients who received both physical therapy and occupational therapy had a better long-term prognosis compared to those who received only one treatment. This study emphasizes the importance of intensive rehabilitation in stroke patients.
Article
Orthopedics
Ching-Yi Wang, Yueh-Chi Chen, Chun-Hou Wang
Summary: PASS score is significantly related to walking status at admission and at 3 months post stroke. The identified 9 items suggest possible interventions for acute rehabilitation.
Article
Clinical Neurology
Alvin S. Das, Elif Gokcal, Robert W. Regenhardt, Mitchell J. Horn, Kristin Schwab, Nader Daoud, Anand Viswanathan, W. Taylor Kimberly, Joshua N. Goldstein, Alessandro Biffi, Natalia Rost, Jonathan Rosand, Lee H. Schwamm, Steven M. Greenberg, M. Edip Gurol
Summary: This study aimed to evaluate whether non-haemorrhagic imaging markers (NHIM) can discriminate cerebral amyloid angiopathy (CAA) from hypertensive cerebral small vessel disease (HTN-cSVD) among patients with isolated lobar intracerebral haemorrhage (isolated-LICH). The study found that NHIM can differentiate HTN-cSVD from CAA using left ventricular hypertrophy (LVH) as a marker for HTN-cSVD.
STROKE AND VASCULAR NEUROLOGY
(2023)
Article
Clinical Neurology
Chun-Juan Wang, Hong-Qiu Gu, Xin-Miao Zhang, Yong Jiang, Hao Li, Janet Prvu Bettger, Xia Meng, Ke-Hui Dong, Run-Qi Wangqin, Xin Yang, Meng Wang, Chelsea Liu, Li-Ping Liu, Bei-Sha Tang, Guo-Zhong Li, Yu-Ming Xu, Zhi-Yi He, Yi Yang, Winnie Yip, Gregg C. Fonarow, Lee H. Schwamm, Ying Xian, Xing-Quan Zhao, Yi-Long Wang, Yongjun Wang, Zixiao Li
Summary: The hospital admission rate for ischemic stroke in China increased from 2005 to 2015, along with an increase in the prevalence of risk factors. Improvements were seen in stroke diagnostics and secondary prevention treatments, as well as a decrease in discharge against medical advice and in-hospital mortality. Disparities between rural and urban hospitals narrowed, but differences in management and outcomes persisted.
STROKE AND VASCULAR NEUROLOGY
(2023)
Article
Clinical Neurology
Jay B. B. Lusk, Ailin Song, Shakthi Unnithan, Hussein R. R. Al-Khalidi, Alen Delic, Adam de Havenon, Valerie Biousse, Matthew Schrag, Sven Poli, Jonathan P. P. Piccini, Ying Xian, Emily C. C. O'Brien, Brian Mac Grory
Summary: This retrospective observational cohort study found an inverse association between atrial fibrillation (AF) and central retinal artery occlusion (CRAO) in a large representative sample of hospitalized patients. This study contributes to our understanding of the relationship between AF and CRAO.
Meeting Abstract
Clinical Neurology
Brian C. Mac Grory, DaJuanicia Holmes, Shreyansh Shah, Adrian F. Hernandez, Roland Matsouaka, Gregg C. Fonarow, Jeffrey L. Saver, Deepak Bhatt, Eric E. Smith, Lee H. Schwamm, Mathew J. Reeves, Martin Unverdorben, Mary Birmingham, Eric D. Peterson, Ying Xian
Article
Clinical Neurology
Lidia M. V. R. Moura, Maria A. A. Donahue, Zhiyu Yan, Louisa H. H. Smith, John Hsu, Joseph P. P. Newhouse, Lee H. H. Schwamm, Sebastien Haneuse, Sonia Hernandez-Diaz, Deborah Blacker
Meeting Abstract
Clinical Neurology
Jay B. Lusk, Ailin Song, Shakthi Unnithan, Hussein R. Al-Khalidi, Jonathan P. Piccini, Ying Xian, Emily C. O'Brien, Brian C. Mac Grory
Meeting Abstract
Clinical Neurology
Shreyansh Shah, Dajuanicia N. Simon, Brian Mac Grory, Roland Matsouaka, Jeffrey L. Saver, Mathew J. Reeves, Deepak Bhatt, Eric E. Smith, Lee H. Schwamm, Gregg C. Fonarow, Adrian F. Hernandez, Eric D. Peterson, Ying Xian
Meeting Abstract
Clinical Neurology
Aaron N. LacKamp, Jeremy M. Weber, Brian Mac Grory, Adrien Caye, Chaeli Stenuf, Tiffany Barkley, Steven Messe, Brooke Alhanti, Rosalia G. Blanco, Gregg C. Fonarow, Ying Xian, Halinder S. Mangat
Article
Neurosciences
Bruno Bacellar Pedreira, Korilyn Sauser Zachrison, Aneesh Singhal, Zhiyu Yan, Jamary Oliveira-Filho, Lee H. H. Schwamm
Summary: The study aimed to examine the differences in outcomes for patients with atrial fibrillation (AF) admitted with a recurrent stroke, stratified according to the presumed etiology of the stroke. The results showed no difference in discharge outcomes between stroke etiologies of cardioembolic and undetermined. This question warrants further investigation in larger samples to better understand the importance of stroke mechanism and secondary prophylaxis.
ARQUIVOS DE NEURO-PSIQUIATRIA
(2023)
Article
Cardiac & Cardiovascular Systems
Shumei Man, Nicole Solomon, Brian Mac Grory, Brooke Alhanti, Ken Uchino, Jeffrey L. Saver, Eric E. Smith, Ying Xian, Deepak L. Bhatt, Lee H. Schwamm, Muhammad Shazam Hussain, Gregg C. Fonarow
Summary: Shorter door-to-needle times are associated with better long-term functional outcomes and lower mortality among older stroke patients treated with IVT only or IVT+EVT. These findings support efforts to accelerate thrombolytic administration in all eligible patients, including those receiving EVT.
Article
Medicine, General & Internal
Brian Mac Grory, DaJuanicia N. Holmes, Roland A. Matsouaka, Shreyansh Shah, Cherylee W. J. Chang, Richard Rison, Jenelle Jindal, Christine Holmstedt, William R. Logan, Candy Corral, Jason S. Mackey, Joey R. Gee, David Bonovich, James Walker, Toby Gropen, Curtis Benesch, Jonathan Dissin, Hemant Pandey, David Wang, Martin Unverdorben, Adrian F. Hernandez, Mathew Reeves, Eric E. Smith, Lee H. Schwamm, Deepak L. Bhatt, Jeffrey L. Saver, Gregg C. Fonarow, Eric D. Peterson, Ying Xian
Summary: The use of oral vitamin K antagonists (VKAs) may increase the risk of complications for patients undergoing endovascular thrombectomy for acute ischemic stroke caused by large vessel occlusion. Recent use of VKAs with an international normalized ratio (INR) greater than 1.7 is associated with a significantly higher risk of symptomatic intracranial hemorrhage (sICH) compared to no use of anticoagulants.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Clinical Neurology
Alvin S. S. Das, Elif Gokcal, Alessandro Biffi, Robert W. W. Regenhardt, Marco Pasi, Avia A. Abramovitz Fouks, Anand Viswanathan, Joshua Goldstein, Lee H. H. Schwamm, Jonathan Rosand, Steven M. M. Greenberg, M. Edip Gurol
Summary: This study examined the association between cerebral amyloid angiopathy (CAA) markers and mixed intracerebral hemorrhage (ICH) with cortical superficial siderosis (cSS). The results showed that patients with mixed ICH/cSS(+) had higher frequencies of CAA imaging markers and a higher risk of ICH recurrence compared to patients without cSS.
Editorial Material
Clinical Neurology
Lee H. Schwamm, Gisele Sampaio Silva
Article
Medicine, General & Internal
Chun-Juan Wang, Hong-Qiu Gu, Li-Xia Zong, Xin-Miao Zhang, Qi Zhou, Yong Jiang, Hao Li, Xia Meng, Xin Yang, Meng Wang, Xiao-Chuan Huo, Run-Qi Wangqin, Yu-Zhang Bei, Xiu-Hui Qi, Xiao-Yun Liu, Shi-Qiang Hu, Zhi-Min Wang, Xing-Quan Zhao, Yi-Long Wang, Li-Ping Liu, Xu-Dong Ma, Louise Morgan, Ying Xian, Lee H. Schwamm, Yong-Jun Wang, Zi-Xiao Li
Summary: A problem-oriented, culturally adapted, targeted quality improvement intervention was evaluated in China to improve reperfusion therapy for acute ischemic stroke patients. The intervention did not improve the reperfusion therapy rate overall, but it showed effectiveness in secondary hospitals.
Article
Geriatrics & Gerontology
Nan Wang, Hanzhang Xu, Jessica S. West, Truls Ostbye, Bei Wu, Ying Xian, Matthew E. Dupre
Summary: This study aimed to assess factors associated with the perceived risk of developing Alzheimer's disease and related dementias (ADRD) and how it related to cognitive function. The findings showed that the perceived risk of developing ADRD was associated with cognitive function, which has important implications for increasing public awareness and developing interventions to prevent ADRD.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)