Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional Heterogeneity

Modulation of transcriptional burst frequency by histone acetylation

(2018) Damien Nicolas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The CRISPR tool kit for genome editing and beyond

(2018) Mazhar Adli   Nature Communications

GCN5 Regulates FGF Signaling and Activates Selective MYC Target Genes during Early Embryoid Body Differentiation

(2018) Li Wang et al.   Stem Cell Reports

Cell population structure prior to bifurcation predicts efficiency of directed differentiation in human induced pluripotent cells

(2017) Rhishikesh Bargaje et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors

(2017) Jayme L. Dahlin et al.   Nature Communications

Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex

(2016) Anzy Miller et al.   DEVELOPMENT

Transition states and cell fate decisions in epigenetic landscapes

(2016) Naomi Moris et al.   NATURE REVIEWS GENETICS

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

(2016) Konstantinos Tzelepis et al.   Cell Reports

Single-Cell-Based Analysis Highlights a Surge in Cell-to-Cell Molecular Variability Preceding Irreversible Commitment in a Differentiation Process

(2016) Angélique Richard et al.   PLOS BIOLOGY

Cell Fate Decision as High-Dimensional Critical State Transition

(2016) Mitra Mojtahedi et al.   PLOS BIOLOGY

Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming

(2015) Calley L. Hirsch et al.   GENES & DEVELOPMENT

Single-Cell Network Analysis Identifies DDIT3 as a Nodal Lineage Regulator in Hematopoiesis

(2015) Cristina Pina et al.   Cell Reports

Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency

(2014) Elsa Abranches et al.   DEVELOPMENT

Validation of noise models for single-cell transcriptomics

(2014) Dominic Grün et al.   NATURE METHODS

Controlling low rates of cell differentiation through noise and ultrahigh feedback

(2014) R. Ahrends et al.   SCIENCE

An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells

(2014) D. A. Turner et al.   Biology Open

Generation and Characterization of a Novel Mouse Embryonic Stem Cell Line with a Dynamic Reporter of Nanog Expression

(2013) Elsa Abranches et al.   PLoS One

Transcriptional Regulation of Lineage Commitment - A Stochastic Model of Cell Fate Decisions

(2013) Jose Teles et al.   PLoS Computational Biology

Single cell lineage analysis of mouse embryonic stem cells at the exit from pluripotency

(2013) J. Trott et al.   Biology Open

Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

(2012) Yosef Buganim et al.   CELL

Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations

(2012) Y. Luo et al.   Journal of the Royal Society Interface

Expression Noise and Acetylation Profiles Distinguish HDAC Functions

(2012) Leehee Weinberger et al.   MOLECULAR CELL

Inferring rules of lineage commitment in haematopoiesis

(2012) Cristina Pina et al.   NATURE CELL BIOLOGY

Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity

(2012) Ben D. MacArthur et al.   NATURE CELL BIOLOGY

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

(2010) Qihuang Jin et al.   EMBO JOURNAL

Functional roles for noise in genetic circuits

(2010) Avigdor Eldar et al.   NATURE

Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells

(2009) Tibor Kalmar et al.   PLOS BIOLOGY

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

A core Klf circuitry regulates self-renewal of embryonic stem cells

(2008) Jianming Jiang et al.   NATURE CELL BIOLOGY