Journal
STEM CELL RESEARCH
Volume 34, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.scr.2018.101380
Keywords
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Funding
- Australian National Health & Medical Research Council [GNT1117596, GNT1079004, GNT1098255]
- Australian Government National Health and Medical Research Council Independent Research Institute
- Victorian Government's Operational Infrastructure Support Program
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We describe the generation and characterization of 5 human induced pluripotent stem cell (iPSC) lines derived from peripheral blood mononuclear cells (PBMCs) of healthy adult individuals. The PBMCs were reprogrammed using non-integrating Sendai viruses containing the reprogramming factors POU5F1 (OCT4), SOX2, KLF4 and MYC. The iPSC lines exhibited a normal karyotype, expressed pluripotency markers and differentiated into cells representative of the three embryonic germ layers. These iPSC lines can be used as controls in studying disease mechanisms.
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