The protein kinase p38α destabilizes p63 to limit epidermal stem cell frequency and tumorigenic potential

Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling

(2016) D. Peng et al.   CANCER RESEARCH

Identification of Susceptibility Loci for Cutaneous Squamous Cell Carcinoma

(2016) Maryam M. Asgari et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma

(2016) Harvind S. Chahal et al.   Nature Communications

Stem Cell Heterogeneity and Plasticity in Epithelia

(2015) Giacomo Donati et al.   Cell Stem Cell

Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation

(2015) E. N. Kouwenhoven et al.   EMBO REPORTS

Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer

(2015) Erica J Childs et al.   NATURE GENETICS

Dual Function of p38α MAPK in Colon Cancer: Suppression of Colitis-Associated Tumor Initiation but Requirement for Cancer Cell Survival

(2014) Jalaj Gupta et al.   CANCER CELL

Inhibition of p38 MAPK Signaling Augments Skin Tumorigenesis via NOX2 Driven ROS Generation

(2014) Liang Liu et al.   PLoS One

Plasticity of epithelial stem cells in tissue regeneration

(2014) C. Blanpain et al.   SCIENCE

Sunlight UV-Induced Skin Cancer Relies upon Activation of the p38  Signaling Pathway

(2013) K. Liu et al.   CANCER RESEARCH

FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma

(2013) Matthew R. Ramsey et al.   JOURNAL OF CLINICAL INVESTIGATION

TCPA: a resource for cancer functional proteomics data

(2013) Jun Li et al.   NATURE METHODS

 Np63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation

(2012) R.-A. Romano et al.   DEVELOPMENT

Critical Appraisal of the Side Population Assay in Stem Cell and Cancer Stem Cell Research

(2011) Anna Golebiewska et al.   Cell Stem Cell

ΔNp63α Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis

(2011) William M. Keyes et al.   Cell Stem Cell

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

(2011) Adam Freund et al.   EMBO JOURNAL

p38 MAP kinase plays a functional role in UVB-Induced mouse skin carcinogenesis

(2011) Sally E. Dickinson et al.   MOLECULAR CARCINOGENESIS

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

(2011) Benjamin Beck et al.   NATURE

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Opposing roles for calcineurin and ATF3 in squamous skin cancer

(2010) Xunwei Wu et al.   NATURE

Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations

(2010) Daiki Miki et al.   NATURE GENETICS

TAp63 Prevents Premature Aging by Promoting Adult Stem Cell Maintenance

(2009) Xiaohua Su et al.   Cell Stem Cell

Hepatocyte Necrosis Induced by Oxidative Stress and IL-1α Release Mediate Carcinogen-Induced Compensatory Proliferation and Liver Tumorigenesis

(2008) Toshiharu Sakurai et al.   CANCER CELL

Sequence variant on 8q24 confers susceptibility to urinary bladder cancer

(2008) Lambertus A Kiemeney et al.   NATURE GENETICS

The kinase p38α serves cell type–specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression

(2008) Chun Kim et al.   NATURE IMMUNOLOGY