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Synthesis of meta-Carboranyl-(S)-homocysteine Sulfoxide

Journal

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
Volume 54, Issue 10, Pages 1579-1582

Publisher

MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1070428018100251

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Funding

  1. Russian Foundation for Basic Research [16-33-60 122]

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New (S)-homocysteine derivatives containing a meta-carborane fragment were synthesized. m-Carboranyl-(S)-homocysteine sulfoxide was obtained as a mixture of diastereoisomers. The reduction of the side-chain carboxy group of N-tert-butoxycarbonyl-(S)-aspartic acid -tert-butyl ester with sodium tetrahydridoborate was not accompanied by racemization.

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