The selenium-containing compound 3-((4-chlorophenyl)selanyl)-1-methyl-1H-indole reverses depressive-like behavior induced by acute restraint stress in mice: modulation of oxido-nitrosative stress and inflammatory pathway

3-(4-Chlorophenylselanyl)-1-methyl-1 H -indole, a new selenium compound elicits an antinociceptive and anti-inflammatory effect in mice

(2018) Paloma T. Birmann et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Organic selenium compounds as potential chemotherapeutic agents for improved cancer treatment

(2018) Valentina Gandin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Targeting glycogen synthase kinase-3 for oxidative stress and neuroinflammation: Opportunities, challenges and future directions for cerebral stroke management

(2018) Anil Kumar Rana et al.   NEUROPHARMACOLOGY

Diselenoamino acid derivatives as GPx mimics and as substrates of TrxR: in vitro and in silico studies

(2018) Jéssie Haigert Sudati et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Antidepressant effects of creatine on amyloid β 1–40 -treated mice: The role of GSK-3β/Nrf 2 pathway

(2018) Julia M. Rosa et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Pharmacological augmentation of endocannabinoid signaling reduces the neuroendocrine response to stress

(2018) Pablo Nicolás Surkin et al.   PSYCHONEUROENDOCRINOLOGY

Selanylimidazopyridine Prevents Lipopolysaccharide-Induced Depressive-Like Behavior in Mice by Targeting Neurotrophins and Inflammatory/Oxidative Mediators

(2018) Micaela Domingues et al.   Frontiers in Neuroscience

Emerging role of amyloid beta in stress response: Implication for depression and diabetes

(2017) Maria Grazia Morgese et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins

(2017) Angela M. Casaril et al.   FREE RADICAL BIOLOGY AND MEDICINE

Safety and efficacy of ebselen for the prevention of noise-induced hearing loss: a randomised, double-blind, placebo-controlled, phase 2 trial

(2017) Jonathan Kil et al.   LANCET

Acute stress regulates phosphorylation of N-methyl- d -aspartate receptor GluN2B at S1284 in hippocampus

(2017) Heng Ai et al.   NEUROSCIENCE

Stressed and Inflamed, Can GSK3 Be Blamed?

(2017) Richard S. Jope et al.   TRENDS IN BIOCHEMICAL SCIENCES

Lymphocyte Levels of Redox-Sensitive Transcription Factors and Antioxidative Enzymes as Indicators of Pro-Oxidative State in Depressive Patients

(2017) Iva Lukic et al.   NEUROPSYCHOBIOLOGY

Acute restraint stress induces specific changes in nitric oxide production and inflammatory markers in the rat hippocampus and striatum

(2016) Hsiao-Jou Cortina Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-  Oligomers in Mice

(2016) J. H. Ledo et al.   JOURNAL OF NEUROSCIENCE

Inflammation Effects on Motivation and Motor Activity: Role of Dopamine

(2016) Jennifer C Felger et al.   NEUROPSYCHOPHARMACOLOGY

Psychosocial stress inhibits additional stress-induced hyperexpression of NO synthases and IL-1β in brain structures

(2016) Anna Gądek-Michalska et al.   Pharmacological Reports

Potential antidepressant-like activity of silymarin in the acute restraint stress in mice: Modulation of corticosterone and oxidative stress response in cerebral cortex and hippocampus

(2016) Vishnu N. Thakare et al.   Pharmacological Reports

Mitochondrial impairment, apoptosis and autophagy in a rat brain as immediate and long-term effects of perinatal phencyclidine treatment — influence of restraint stress

(2016) Gordana Jevtić et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Involvement of monoaminergic system in the antidepressant-like effect of (octylseleno)-xylofuranoside in the mouse tail suspension test

(2016) Lucimar M. Pinto Brod et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Increased activities of both superoxide dismutase and catalase were indicators of acute depressive episodes in patients with major depressive disorder

(2016) Meng-Chang Tsai et al.   PSYCHIATRY RESEARCH

Acute restraint stress induces rapid changes in central redox status and protective antioxidant genes in rats

(2016) Jereme G. Spiers et al.   PSYCHONEUROENDOCRINOLOGY

Effects of the potential lithium-mimetic, ebselen, on impulsivity and emotional processing

(2016) Charles Masaki et al.   PSYCHOPHARMACOLOGY

Paliperidone Prevents Brain Toll-Like Receptor 4 Pathway Activation and Neuroinflammation in Rat Models of Acute and Chronic Restraint Stress

(2015) KS MacDowell et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Posttraumatic Stress Disorder-Like Induction Elevates  -Amyloid Levels, Which Directly Activates Corticotropin-Releasing Factor Neurons to Exacerbate Stress Responses

(2015) N. J. Justice et al.   JOURNAL OF NEUROSCIENCE

Effect of the Putative Lithium Mimetic Ebselen on Brain Myo-Inositol, Sleep and Emotional Processing in Humans

(2015) Nisha Singh et al.   NEUROPSYCHOPHARMACOLOGY

7-Fluoro-1,3-diphenylisoquinoline-1-amine abolishes depressive-like behavior and prefrontal cortical oxidative damage induced by acute restraint stress in mice

(2015) Ana Paula Pesarico et al.   PHYSIOLOGY & BEHAVIOR

Evaluation of the toxicity of α-(phenylselanyl) acetophenone in mice

(2015) Angela M. Casaril et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Sonochemistry: An efficient alternative to the synthesis of 3-selanylindoles using CuI as catalyst

(2015) Beatriz M. Vieira et al.   ULTRASONICS SONOCHEMISTRY

Modulatory Activity of Soluble Beta Amyloid on HPA Axis Function in Rats

(2015) Maria Morgese et al.   CURRENT PHARMACEUTICAL DESIGN

Toll-like 4 receptor inhibitor TAK-242 decreases neuroinflammation in rat brain frontal cortex after stress

(2014) Iciar Gárate et al.   Journal of Neuroinflammation

Antidepressant-like activity of dehydrozingerone: Involvement of the serotonergic and noradrenergic systems

(2014) Débora M. Martinez et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Rodent Models of Depression: Neurotrophic and Neuroinflammatory Biomarkers

(2014) Mikhail Stepanichev et al.   Biomed Research International

Inflammasome-derived IL-1β production induces nitric oxide–mediated resistance to Leishmania

(2013) Djalma S Lima-Junior et al.   NATURE MEDICINE

Inflammatory cytokines in depression: Neurobiological mechanisms and therapeutic implications

(2013) J.C. Felger et al.   NEUROSCIENCE

Agmatine abolishes restraint stress-induced depressive-like behavior and hippocampal antioxidant imbalance in mice

(2013) Andiara E. Freitas et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressants

(2013) Caroline A. Browne et al.   Frontiers in Pharmacology

Fluoxetine modulates hippocampal cell signaling pathways implicated in neuroplasticity in olfactory bulbectomized mice

(2012) Andiara E. Freitas et al.   BEHAVIOURAL BRAIN RESEARCH

Stress-Induced Neuroinflammation: Role of the Toll-Like Receptor-4 Pathway

(2012) Iciar Gárate et al.   BIOLOGICAL PSYCHIATRY

Do antioxidants impair signaling by reactive oxygen species and lipid oxidation products?

(2012) Etsuo Niki   FEBS LETTERS

Propranolol reduces cognitive deficits, amyloid β levels, tau phosphorylation and insulin resistance in response to chronic corticosterone administration

(2012) Marta Dobarro et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Protective Effects of Ascorbic Acid on Behavior and Oxidative Status of Restraint-Stressed Mice

(2012) Morgana Moretti et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Allen Brain Atlas: an integrated spatio-temporal portal for exploring the central nervous system

(2012) Susan M. Sunkin et al.   NUCLEIC ACIDS RESEARCH

Melatonin and structurally similar compounds have differing effects on inflammation and mitochondrial function in endothelial cells under conditions mimicking sepsis

(2011) D.A. Lowes et al.   BRITISH JOURNAL OF ANAESTHESIA

Effects of long-term antidepressant treatment on oxidative status in major depressive disorder: A 24-week follow-up study

(2011) Vahap Ozan Kotan et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Depression and Hypothalamic-Pituitary-Adrenal Activation: A Quantitative Summary of Four Decades of Research

(2011) Cinnamon Stetler et al.   PSYCHOSOMATIC MEDICINE

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness

(2010) Michael Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Nitric Oxide at the Crossroad of Immunoneuroendocrine Interactions

(2009) Valeria Rettori et al.   Annals of the New York Academy of Sciences

Involvement of NOX2 in the Development of Behavioral and Pathologic Alterations in Isolated Rats

(2009) Stefania Schiavone et al.   BIOLOGICAL PSYCHIATRY

Mechanism of glucocorticoid-induced oxidative stress in rat hippocampal slice cultures

(2009) Jung-Man You et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Restraint stress in biobehavioral research: Recent developments

(2009) Tatyana Buynitsky et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Stress as a neuroinflammatory condition in brain: Damaging and protective mechanisms

(2008) Borja García-Bueno et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The course of nitric oxide and superoxide dismutase during treatment of bipolar depressive episode

(2007) Salih Selek et al.   JOURNAL OF AFFECTIVE DISORDERS

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE

Neurohormonal-cytokine interactions: Implications for inflammation, common human diseases and well-being

(2007) Ilia J. Elenkov   NEUROCHEMISTRY INTERNATIONAL