Mechanisms of fear learning and extinction: synaptic plasticity–fear memory connection

Excitatory connections between the prelimbic and infralimbic medial prefrontal cortex show a role for the prelimbic cortex in fear extinction

(2018) Roger Marek et al.   NATURE NEUROSCIENCE

Hippocampus-driven feed-forward inhibition of the prefrontal cortex mediates relapse of extinguished fear

(2018) Roger Marek et al.   NATURE NEUROSCIENCE

Fear extinction requires infralimbic cortex projections to the basolateral amygdala

(2018) Daniel W. Bloodgood et al.   Translational Psychiatry

Encoding of danger by parabrachial CGRP neurons

(2018) Carlos A. Campos et al.   NATURE

Prefrontal cortical control of a brainstem social behavior circuit

(2017) Tamara B Franklin et al.   NATURE NEUROSCIENCE

The central amygdala controls learning in the lateral amygdala

(2017) Kai Yu et al.   NATURE NEUROSCIENCE

Encoding of Discriminative Fear Memory by Input-Specific LTP in the Amygdala

(2017) Woong Bin Kim et al.   NEURON

Memory Erasure Experiments Indicate a Critical Role of CaMKII in Memory Storage

(2017) Tom Rossetti et al.   NEURON

Amount of fear extinction changes its underlying mechanisms

(2017) Bobae An et al.   eLife

New Learning and Unlearning: Strangers or Accomplices in Threat Memory Attenuation?

(2016) Roger L. Clem et al.   TRENDS IN NEUROSCIENCES

Revisiting the Role of Infralimbic Cortex in Fear Extinction with Optogenetics

(2015) F. H. Do-Monte et al.   JOURNAL OF NEUROSCIENCE

Sensory Inputs to Intercalated Cells Provide Fear-Learning Modulated Inhibition to the Basolateral Amygdala

(2015) Douglas Asede et al.   NEURON

mGluR2/3 in the Lateral Amygdala is Required for Fear Extinction: Cortical Input Synapses onto the Lateral Amygdala as a Target Site of the mGluR2/3 Action

(2015) Jihye Kim et al.   NEUROPSYCHOPHARMACOLOGY

Selective Control of Fear Expression by Optogenetic Manipulation of Infralimbic Cortex after Extinction

(2015) Hyung-Su Kim et al.   NEUROPSYCHOPHARMACOLOGY

Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders

(2015) N. Singewald et al.   PHARMACOLOGY & THERAPEUTICS

Prefrontal and Auditory Input to Intercalated Neurons of the Amygdala

(2015) Cornelia Strobel et al.   Cell Reports

Prefrontal inputs to the amygdala instruct fear extinction memory formation

(2015) O. Bukalo et al.   Science Advances

Mechanisms to medicines: elucidating neural and molecular substrates of fear extinction to identify novel treatments for anxiety disorders

(2014) Olena Bukalo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Long-term potentiation at excitatory synaptic inputs to the intercalated cell masses of the amygdala

(2014) Chiung-Chun Huang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Decreased Anxiety-Like Behavior and G q/11-Dependent Responses in the Amygdala of Mice Lacking TRPC4 Channels

(2014) A. Riccio et al.   JOURNAL OF NEUROSCIENCE

Pathway-Selective Adjustment of Prefrontal-Amygdala Transmission during Fear Encoding

(2014) M. Arruda-Carvalho et al.   JOURNAL OF NEUROSCIENCE

Synaptic Plasticity Associated with a Memory Engram in the Basolateral Amygdala

(2014) A. Nonaka et al.   JOURNAL OF NEUROSCIENCE

Engineering a memory with LTD and LTP

(2014) Sadegh Nabavi et al.   NATURE

Neuronal encoding of the switch from specific to generalized fear

(2014) Supriya Ghosh et al.   NATURE NEUROSCIENCE

Long-Range Connectivity Defines Behavioral Specificity of Amygdala Neurons

(2014) Verena Senn et al.   NEURON

Amygdala Microcircuits Controlling Learned Fear

(2014) Sevil Duvarci et al.   NEURON

Optogenetics to study the circuits of fear- and depression-like behaviors: A critical analysis

(2014) Catherine Belzung et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Optogenetic dissection of amygdala functioning

(2014) Ryan T. LaLumiere   Frontiers in Behavioral Neuroscience

Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression

(2013) Julien Courtin et al.   NATURE

Experience-dependent modification of a central amygdala fear circuit

(2013) Haohong Li et al.   NATURE NEUROSCIENCE

Synaptic Encoding of Fear Extinction in mPFC-amygdala Circuits

(2013) Jun-Hyeong Cho et al.   NEURON

The synaptic plasticity and memory hypothesis: encoding, storage and persistence

(2013) T. Takeuchi et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Learning and reconsolidation implicate different synaptic mechanisms

(2013) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Creating a False Memory in the Hippocampus

(2013) S. Ramirez et al.   SCIENCE

Long-Term Neural Correlates of Reversible Fear Learning in the Lateral Amygdala

(2012) B. An et al.   JOURNAL OF NEUROSCIENCE

Neural and cellular mechanisms of fear and extinction memory formation

(2012) Caitlin A. Orsini et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Generation of a Synthetic Memory Trace

(2012) A. R. Garner et al.   SCIENCE

Modulation of medial prefrontal cortical activity using in vivo recordings and optogenetics

(2012) Guangchen Ji et al.   Molecular Brain

Controlling the Elements: An Optogenetic Approach to Understanding the Neural Circuits of Fear

(2011) Joshua P. Johansen et al.   BIOLOGICAL PSYCHIATRY

Physiological identification and infralimbic responsiveness of rat intercalated amygdala neurons

(2011) Alon Amir et al.   JOURNAL OF NEUROPHYSIOLOGY

Different Fear States Engage Distinct Networks within the Intercalated Cell Clusters of the Amygdala

(2011) D. Busti et al.   JOURNAL OF NEUROSCIENCE

Central Amygdala Activity during Fear Conditioning

(2011) S. Duvarci et al.   JOURNAL OF NEUROSCIENCE

Functional connectivity of the main intercalated nucleus of the mouse amygdala

(2011) Mirosława Mańko et al.   JOURNAL OF PHYSIOLOGY-LONDON

Coactivation of thalamic and cortical pathways induces input timing–dependent plasticity in amygdala

(2011) Jun-Hyeong Cho et al.   NATURE NEUROSCIENCE

Optogenetics in Neural Systems

(2011) Ofer Yizhar et al.   NEURON

Memory for Fear Extinction Requires mGluR5-Mediated Activation of Infralimbic Neurons

(2010) Darah E. Fontanez-Nuin et al.   CEREBRAL CORTEX

Neuronal circuits of fear extinction

(2010) Cyril Herry et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The medial geniculate, not the amygdala, as the root of auditory fear conditioning

(2010) Norman M. Weinberger   HEARING RESEARCH

Endogenous GluR1-containing AMPA receptors translocate to asymmetric synapses in the lateral amygdala during the early phase of fear memory formation: An electron microscopic immunocytochemical study

(2010) Hermina Nedelescu et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Dissociation of within- and between-Session Extinction of Conditioned Fear

(2010) W. Plendl et al.   JOURNAL OF NEUROSCIENCE

Encoding of conditioned fear in central amygdala inhibitory circuits

(2010) Stephane Ciocchi et al.   NATURE

Synaptic correlates of fear extinction in the amygdala

(2010) Taiju Amano et al.   NATURE NEUROSCIENCE

Dissociable Roles of Prelimbic and Infralimbic Cortices, Ventral Hippocampus and Basolateral Amygdala in the Expression and Extinction of Conditioned Fear

(2010) Demetrio Sierra-Mercado et al.   NEUROPSYCHOPHARMACOLOGY

Plastic Synaptic Networks of the Amygdala for the Acquisition, Expression, and Extinction of Conditioned Fear

(2010) Hans-Christian Pape et al.   PHYSIOLOGICAL REVIEWS

Optical activation of lateral amygdala pyramidal cells instructs associative fear learning

(2010) Joshua P. Johansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium-Permeable AMPA Receptor Dynamics Mediate Fear Memory Erasure

(2010) R. L. Clem et al.   SCIENCE

Essential Role for TRPC5 in Amygdala Function and Fear-Related Behavior

(2009) Antonio Riccio et al.   CELL

Extinction of cued fear memory involves a distinct form of depotentiation at cortical input synapses onto the lateral amygdala

(2009) Ingie Hong et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cornering the Fear Engram: Long-Term Synaptic Changes in the Lateral Nucleus of the Amygdala after Fear Conditioning

(2009) J.-T. Kwon et al.   JOURNAL OF NEUROSCIENCE

Early extinction after fear conditioning yields a context-independent and short-term suppression of conditional freezing in rats

(2009) C.-h. Chang et al.   LEARNING & MEMORY

Selective Erasure of a Fear Memory

(2009) J.-H. Han et al.   SCIENCE

Extinction-Reconsolidation Boundaries: Key to Persistent Attenuation of Fear Memories

(2009) M.-H. Monfils et al.   SCIENCE

Dissociable Roles for the Ventromedial Prefrontal Cortex and Amygdala in Fear Extinction: NR2B Contribution

(2008) F. Sotres-Bayon et al.   CEREBRAL CORTEX

A Biologically Realistic Network Model of Acquisition and Extinction of Conditioned Fear Associations in Lateral Amygdala Neurons

(2008) Guoshi Li et al.   JOURNAL OF NEUROPHYSIOLOGY

Fear Conditioning and Extinction Differentially Modify the Intrinsic Excitability of Infralimbic Neurons

(2008) E. Santini et al.   JOURNAL OF NEUROSCIENCE

Evidence for recovery of fear following immediate extinction in rats and humans

(2008) D. Schiller et al.   LEARNING & MEMORY

Immediate extinction causes a less durable loss of performance than delayed extinction following either fear or appetitive conditioning

(2008) A. M. Woods et al.   LEARNING & MEMORY

Amygdala intercalated neurons are required for expression of fear extinction

(2008) Ekaterina Likhtik et al.   NATURE

Switching on and off fear by distinct neuronal circuits

(2008) Cyril Herry et al.   NATURE

Neuropeptide S-Mediated Control of Fear Expression and Extinction: Role of Intercalated GABAergic Neurons in the Amygdala

(2008) Kay Jüngling et al.   NEURON

Unconditioned stimulus pathways to the amygdala: Effects of lesions of the posterior intralaminar thalamus on foot-shock-induced c-Fos expression in the subdivisions of the lateral amygdala

(2008) E. Lanuza et al.   NEUROSCIENCE

cAMP/PKA signaling and RIM1  mediate presynaptic LTP in the lateral amygdala

(2008) E. Fourcaudot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA