Journal
ACTA DERMATO-VENEREOLOGICA
Volume 96, Issue 3, Pages 361-366Publisher
ACTA DERMATO-VENEREOLOGICA
DOI: 10.2340/00015555-2280
Keywords
haemodialysis; IFSI classification; itch; pruritus; uremic itch; xerosis
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Funding
- Fresenius Medical Care Deutschland GmbH, Germany
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The German Epidemiological Haemodialysis Itch Study (GEHIS) has shown that more than one-third of haemodialysis patients have chronic itch (CI). As part of GE-HIS, 216 patients with current CI were offered a dermatological examination, of whom 177 were investigated. According to the clinical classification of the International Forum for the Study of Itch (IFSI), 43.5% (n=77) of the patients examined had CI with no skin lesions (IFSI II), 37.9% (n=67) had secondary scratch lesions (IFSI HI), and 18.6% (n=33) primarily had diseased skin (IFSI I). Severity of CI and itch-related quality of life (ItchyQoL) showed a significant association only with IFSI HI. Of the patients in this study, 89.8% (n=159) had xerosis cutis. Only 40.4% (n=80) had ever sought medical help for CI, 46.4% (n=32) of whom were in the category IFSI III. Only 32.4% (n=77) had ever received any treatment for CI and these patients had significantly more severe CI. The current analyses demonstrate that CI is a frequently disregarded symptom in haemodialysis patients.
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