Activation of orexin system facilitates anesthesia emergence and pain control

Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models

(2017) Yoko Irukayama-Tomobe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemogenetics revealed: DREADD occupancy and activation via converted clozapine

(2017) Juan L. Gomez et al.   SCIENCE

Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia

(2016) Norman E. Taylor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concurrent and robust regulation of feeding behaviors and metabolism by orexin neurons

(2014) Ayumu Inutsuka et al.   NEUROPHARMACOLOGY

Designer receptor manipulations reveal a role of the locus coeruleus noradrenergic system in isoflurane general anesthesia

(2014) E. M. Vazey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Orexin (Hypocretin) Receptor Agonists and Antagonists for Treatment of Sleep Disorders

(2013) Michihiro Mieda et al.   CNS DRUGS

Orexin-A Facilitates Emergence from Propofol Anesthesia in the Rat

(2012) Li-Na Zhang et al.   ANESTHESIA AND ANALGESIA

Orexin A Decreases Ketamine-Induced Anesthesia Time in the Rat: The Relevance to Brain Noradrenergic Neuronal Activity

(2009) Ryuji Tose et al.   ANESTHESIA AND ANALGESIA

Activation of orexin signal in basal forebrain facilitates the emergence from sevoflurane anesthesia in rat

(2009) Hailong Dong et al.   NEUROPEPTIDES

GABAA receptor membrane trafficking regulates spine maturity

(2009) T. C. Jacob et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The dual role of the orexin/hypocretin system in modulating wakefulness and respiratory drive

(2008) Christian Gestreau et al.   CURRENT OPINION IN PULMONARY MEDICINE

General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

(2008) Nicholas P. Franks   NATURE REVIEWS NEUROSCIENCE

An essential role for orexins in emergence from general anesthesia

(2008) M. B. Kelz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GABAA receptor subtypes underlying general anesthesia

(2007) Robert P. Bonin et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR