Article
Virology
Natsumi Noji, Kaori Okayama, Mizue Oda, Atsuyoshi Shimada, Mitsuaki Okodo
Summary: The study validated a simple manual microdissection (MMD) maneuver and investigated the HPV infection status of single cells isolated from women with multiple-type infections. The MMD procedure efficiently collected single cells, and most multiple-type infection samples exhibited only one genotype.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Public, Environmental & Occupational Health
Jaime M. Kiff, Madisen Cotter, Elizabeth G. Munro, Molly E. Leonard, Terry K. Morgan, Amanda S. Bruegl
Summary: This study suggests that hrHPV testing may be more accurate than co-testing in postmenopausal women, and cytology does not provide additional clinical value in this population. Women with persistent hrHPV were more likely to develop CIN2+ compared to those who cleared the virus, but no specific risk factors for persistence were identified in the study.
JOURNAL OF WOMENS HEALTH
(2021)
Article
Microbiology
Kaori Okayama, Toshiyuki Sasagawa, Koji Teruya, Mizue Oda, Masahiko Fujii, Hirokazu Kimura, Mitsuaki Okodo
Summary: This study found an association between HPV genotypes and MNCs, high-risk HPV genotypes may be related to atypical changes in MNC morphology, and MNCs may predict squamous intraepithelial lesions.
Article
Obstetrics & Gynecology
Sara Kasraei, Akram Ghahghaei-nezamabadi, Akram Seifollahi, Faezeh Aghajani, Amin Nakhostin-Ansari, Neda Zarei, Afsaneh Tehranian
Summary: There is no significant difference in the risk of high-grade CIN lesions between patients with negative Pap test and positive other HR-HPV compared to patients with positive HPV 16/18. Moreover, there seems to be a high risk of losing patients during the 1-year follow-up.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2022)
Article
Obstetrics & Gynecology
Neal M. Lonky, Lanfang Xu, Diane M. Da Silva, Juan C. Felix, Chun Chao
Summary: This study aimed to evaluate the risk of high-grade cervical lesion diagnosed through colposcopy in women with human papillomavirus vaccination compared to women without vaccination. The results showed that vaccination history did not significantly lower the odds of a cervical intraepithelial neoplasm grade 2+ diagnosis.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Medicine, General & Internal
Mateja Sladic, Pepita Taneska, Branko Cvjeticanin, Mojca Velikonja, Vladimir Smrkolj, Spela Smrkolj
Summary: Persistent infection with HPV is the main cause of cervical precancerous lesions and cancers. HPV vaccines have high efficacy in preventing high-grade CIN3, especially in HPV-naive populations. However, the vaccines do not provide complete protection against all oncogenic HPV genotypes, leading to reported cases of precancerous cervical lesions in vaccinated individuals. Regular cervical screening programs are still recommended for HPV-vaccinated women.
MEDICINA-LITHUANIA
(2022)
Article
Pathology
Daniel L. Miller, Ashleigh Graham, Katelynn E. Davis, Harsimar Kaur, Marissa White, Zahra Maleki, Erika F. Rodriguez
Summary: This retrospective analysis focused on Black and White women with negative cytology and positive high-risk HPV results. The study found disparities in follow-up and diagnosis between the two racial groups.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY
(2022)
Article
Oncology
Huei-Jean Huang, Hsiu-Jung Tung, Lan-Yan Yang, Angel Chao, Yun-Hsin Tang, Hung-Hsueh Chou, Wei-Yang Chang, Ren-Chin Wu, Chu-Chun Huang, Chiao-Yun Lin, Min-Jie Liao, Wei-Chun Chen, Cheng-Tao Lin, Min-Yu Chen, Kuan-Gen Huang, Chin-Jung Wang, Ting-Chang Chang, Chyong-Huey Lai
Summary: This observational study investigated the long-term outcomes and HPV genotype changes after conization for high-grade cervical intraepithelial neoplasia (HG-CIN). Results showed that active surveillance may reduce the severity of progression to cancer, and a majority of patients with recurrent CIN2+ had persistent type-specific HPV infections. Effective therapeutic vaccines for such cases are still needed.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Obstetrics & Gynecology
Diede L. Loopik, Lisanne M. Koenjer, Albert G. Siebers, Willem J. G. Melchers, Ruud L. M. Bekkers
Summary: This study compared the effectiveness of the new high-risk human papillomavirus-based cervical cancer screening program with the previous cytology-based screening program in the Netherlands. The findings showed that high-risk human papillomavirus-based screening can increase the detection of high-grade cervical intraepithelial neoplasia, but also comes with a higher risk of overdiagnosis.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Obstetrics & Gynecology
Line Winther Gustafson, Anne Hammer, Mary Holten Bennetsen, Christina Blach Kristensen, Huda Majeed, Lone Kjeld Petersen, Berit Andersen, Pinar Bor
Summary: The detection of CIN2+ in women aged >= 45 years with TZ3 is underestimated if relying on biopsy results alone. To reduce the risk of underdiagnosis and overtreatment, future studies should explore the use of new biomarkers for risk stratification.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Editorial Material
Obstetrics & Gynecology
Line W. Gustafson, Lone Kjeld Petersen, Pinar Bor, Berit Andersen, Anne Hammer
Summary: Despite significant declines in cervical cancer incidence and mortality rates due to screening, older women continue to experience high rates of cervical cancer, the reasons for which remain unclear. Age-related changes to the cervix can impair the sensitivity of screening and effectiveness of colposcopy in older women.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2021)
Article
Immunology
Takeo Shibata, Sumit Shah, Teresa Evans, Hannah Coleman, Benjamin J. Lieblong, Horace J. Spencer, Charles M. Quick, Toshiyuki Sasagawa, Owen W. Stephens, Erich Peterson, Donald Johann, Yong-Chen Lu, Mayumi Nakagawa
Summary: The use of high-throughput sequencing has shown that HPV vaccine can induce specific T cell expansion in both peripheral blood and cervical tissue. This approach not only confirms the presence of vaccine-specific T cells in the body, but also provides a novel method to assess vaccine-specific responses in various anatomical areas.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Infectious Diseases
Hong-Fang Zhi, Liu-Feng Yang, Jing Ge, Xuan-Tao Yang
Summary: This study analyzed the status of human papillomavirus (HPV) infections in women in Yunnan, China and their correlation with the grade of cervical intraepithelial neoplasia (CIN). The study found that HPV infection in Yunnan was dominated by single infection and high-risk HPV types. Patients aged 30 to 45 years had a higher incidence of high-grade squamous intraepithelial lesions (HSIL), and the most common high-risk HPV subtypes were HPV16, HPV58, and HPV52.
INFECTION AND DRUG RESISTANCE
(2022)
Article
Immunology
Barbara Gardella, Alberto Agarossi, Mattia Dominoni, Isabella Pagano, Susanna Del Frati, Maria Di Giminiani, Selene Cammarata, Chiara Melito, Marianna Francesca Pasquali, Lucia Zanchi, Valeria Savasi, Arsenio Spinillo
Summary: The aim of this study is to evaluate the risk factors for development of CIN2+ in women living with HIV. The results show that women with good immune status and negative Pap smear and HR-HPV test have a low risk for CIN2+.
Article
Oncology
Sayaka Ikeda, Yutaka Ueda, Megumi Hara, Asami Yagi, Tetsuhisa Kitamura, Yuri Kitamura, Hiroshi Konishi, Tadao Kakizoe, Masayuki Sekine, Takayuki Enomoto, Tomotaka Sobue
Summary: This nationwide case-control study in Japan demonstrated a substantial risk reduction in abnormal cytology and CIN among women who did versus those who did not receive HPV vaccination.
Article
Medicine, General & Internal
Sarah E. Stumbar, Nana Aisha Garba, Maria Stevens, Elizabeth Gray, Emiri Uchimaya, Prasad Bhoite
Summary: This study suggests that a brief, interactive sexual history workshop, including a lecture and standardized patient case, is an effective component of medical training for improving students' knowledge of inclusive sexual history and transgender health care. Students perceived the standardized patient case as realistic and found the debriefing session helpful in identifying their own strengths and weaknesses in providing care for transgender patients. The findings also highlight the importance and feasibility of merging teaching on sexual history and transgender health care in undergraduate medical education curricula.
SOUTHERN MEDICAL JOURNAL
(2021)
Article
Primary Health Care
Maria Syl D. de la Cruz, Tomoko Sairenji, Sarah E. Stumbar, Dolapo Babalola, Alexander W. Chessman
Summary: This study aimed to explore attitudes and preferences regarding a national family medicine sub-I curriculum among stakeholders, including unique characteristics of family medicine sub-Is, recommendations for core skills and objectives, and evaluation methods. The study found that adaptability and specificity in evaluation are important aspects of a family medicine sub-I curriculum.
Editorial Material
Primary Health Care
Sarah E. Stumbar
Article
Medicine, General & Internal
Sarah E. Stumbar, Nana Aisha Garba, MariaSyl de la Cruz, Prasad Bhoite, Emiri Uchiyama
Summary: The study aimed to assess students' perceptions and satisfaction with a workshop on sexual history taking and transgender health. The results showed that students overwhelmingly believed that the participation of sexual and gender minority community members as standardized patients in the workshop helped improve their knowledge, attitudes, and skills in providing care for this population.
SOUTHERN MEDICAL JOURNAL
(2022)
Article
Medicine, General & Internal
Sarah E. Stumbar, Marthena Phan, Marquita Samuels
Summary: This study evaluated the impact of a narrative medicine elective course on medical students at Florida International University Herbert Wertheim College of Medicine. The results showed that students believed the course taught them strategies for improving patient care and personal well-being, which they planned to continue practicing in the future. These findings indicate that the practice of narrative medicine during medical school may provide opportunities to promote reflection and resilience.
SOUTHERN MEDICAL JOURNAL
(2023)
Letter
Education, Scientific Disciplines
Suzanne Minor, Sarah E. Stumbar
Editorial Material
Medicine, General & Internal
Sarah Eisenstein Stumbar
Summary: In this narrative medicine essay, a family physician reflects on her deceased aunt's life in the 1970s and explores the shared genetics that connect their histories. Through her writing, she envisions a future that her aunt could not have experienced.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Medicine, General & Internal
Sarah E. Stumbar, Nana Aisha Garba, Suzanne Minor, Rebecca Toonkel, Rodolfo Bonnin, Vivian Obeso
Summary: Recent disease modeling indicates an increase in the frequency and severity of pandemics. Medical educators need to learn from the COVID-19 experience to develop systematic strategies for training medical students in the management of emerging diseases. This study reports on a survey conducted among students at Florida International University Herbert Wertheim College of Medicine regarding their experiences in caring for COVID-19 patients.
SOUTHERN MEDICAL JOURNAL
(2023)
Article
Medicine, General & Internal
Shweta Akhouri, Anna Virani, Suzanne Minor, Marquita N. Samuels, Sarah E. Stumbar
Summary: The flipped classroom approach enhances engagement and learning by allowing students to learn independently before applying knowledge in group settings. During the COVID-19 pandemic, electronic learning methodologies were widely used to ensure student safety and continue remote teaching. Student-led teaching provides innovative ways to deliver key content and allows students to teach their peers.
SOUTHERN MEDICAL JOURNAL
(2023)
Article
Medicine, General & Internal
Sahar Ajabshir, Sarah Stumbar, Innah Lachica, Kevin Gates, Zafar Qureshi, Fatma Huffman
Summary: The study finds a high prevalence of nutrition-related chronic diseases among uninsured adults in South Florida, particularly obesity and hypertension. This highlights the need for tailored nutrition education programs in free clinic settings.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Education, Scientific Disciplines
Suzanne Minor, Sarah Stumbar
Summary: Scholarly writing and working in teams are essential skills for medical education faculty. Collaborative writing brings together team members from different departments, professions, and universities to maximize resources and skill sets for high-quality projects and manuscripts. This article provides detailed guidance for planning and successfully writing medical education submissions collaboratively.
MEDICAL SCIENCE EDUCATOR
(2022)
Letter
Medicine, General & Internal
Sarah E. Stumbar, Marquita Samuels, Suzanne Minor
SOUTHERN MEDICAL JOURNAL
(2021)
Article
Health Policy & Services
Frederick Anderson, Alan L. Wells, Lisa Bard Levine, Sarah E. Stumbar, Michael Maurer, Lisa Gwynn
Summary: The MAVEN Project in Miami, Florida piloted telehealth consults between primary care providers and specialists in three clinics for the uninsured. Preliminary findings suggest that this approach may improve care quality, provider knowledge, and confidence, showcasing innovative healthcare delivery for the uninsured.
JOURNAL OF HEALTH CARE FOR THE POOR AND UNDERSERVED
(2021)
Meeting Abstract
Medicine, General & Internal
Joseph Jude Burns, Maria K. Hargroves, Sarah E. Stumbar
SOUTHERN MEDICAL JOURNAL
(2021)
