Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes

Inflammatory stress of pancreatic beta cells drives release of extracellular heat-shock protein 90α

(2017) Gail J. Ocaña et al.   IMMUNOLOGY

Identification of HSP90 inhibitors as a novel class of senolytics

(2017) Heike Fuhrmann-Stroissnigg et al.   Nature Communications

Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes

(2016) Renecia A. Watkins et al.   Translational Research

Staging Presymptomatic Type 1 Diabetes: A Scientific Statement of JDRF, the Endocrine Society, and the American Diabetes Association

(2015) Richard A. Insel et al.   DIABETES CARE

Predictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY)

(2015) Andrea K. Steck et al.   DIABETES CARE

Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms

(2015) Flora Brozzi et al.   DIABETOLOGIA

Drivers of age-related inflammation and strategies for healthspan extension

(2015) Emily L. Goldberg et al.   IMMUNOLOGICAL REVIEWS

Nonparametric tests

(2014) Martin Krzywinski et al.   NATURE METHODS

Established and emerging biomarkers for the prediction of type 1 diabetes: a systematic review

(2014) Renecia A. Watkins et al.   Translational Research

Aberrant Expression and Secretion of Heat Shock Protein 90 in Patients with Bullous Pemphigoid

(2013) Stefan Tukaj et al.   PLoS One

Restoration of the Unfolded Protein Response in Pancreatic   Cells Protects Mice Against Type 1 Diabetes

(2013) F. Engin et al.   Science Translational Medicine

The pancreatic β cell and type 1 diabetes: innocent bystander or active participant?

(2013) Scott A. Soleimanpour et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Islet  -Cell Endoplasmic Reticulum Stress Precedes the Onset of Type 1 Diabetes in the Nonobese Diabetic Mouse Model

(2012) S. A. Tersey et al.   DIABETES

Fall in C-Peptide During First 2 Years From Diagnosis: Evidence of at Least Two Distinct Phases From Composite Type 1 Diabetes TrialNet Data

(2012) C. J. Greenbaum et al.   DIABETES

Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes

(2012) I. Marhfour et al.   DIABETOLOGIA

Secreted heat shock protein-90 (Hsp90) in wound healing and cancer

(2011) Wei Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

How Does Type 1 Diabetes Develop?: The Notion of Homicide or  -Cell Suicide Revisited

(2011) M. A. Atkinson et al.   DIABETES

Glucose Excursions Between States of Glycemia With Progression to Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1)

(2010) J. M. Sosenko et al.   DIABETES

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Progression to Diabetes in Relatives of Type 1 Diabetic Patients: Mechanisms and Mode of Onset

(2009) E. Ferrannini et al.   DIABETES

Trends of Earlier and Later Responses of C-peptide to Oral Glucose Challenges With Progression to Type 1 Diabetes in Diabetes Prevention Trial-Type 1 Participants

(2009) J. M. Sosenko et al.   DIABETES CARE

Assessing the Performance of Prediction Models

(2009) Ewout W. Steyerberg et al.   EPIDEMIOLOGY

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results

(2008) Jeffrey L Mahon et al.   PEDIATRIC DIABETES