The APOE ε4 allele is associated with a reduction in FEV1/FVC in women: A cross-sectional analysis of the Long Life Family Study

Genome-wide association study on the FEV 1 /FVC ratio in never-smokers identifies HHIP and FAM13A

(2017) Diana A. van der Plaat et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Chronic Hypoxia Accentuates Dysanaptic Lung Growth

(2016) Conrado J. Llapur et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Emerging Roles of Apolipoprotein E and Apolipoprotein A-I in the Pathogenesis and Treatment of Lung Disease

(2016) Xianglan Yao et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Age, APOE and sex: Triad of risk of Alzheimer’s disease

(2016) Brandalyn C. Riedel et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Association Between Mortality and Heritability of the Scale of Aging Vigor in Epidemiology

(2016) Jason L. Sanders et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Health and function of participants in the Long Life Family Study: A comparison with other cohorts

(2016) Anne B. Newman et al.   Aging-US

Serum Apolipoprotein A-I and Large High-Density Lipoprotein Particles Are Positively Correlated with FEV1in Atopic Asthma

(2015) Amisha V. Barochia et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Apolipoprotein E deficiency and high-fat diet cooperate to trigger lipidosis and inflammation in the lung via the toll-like receptor 4 pathway

(2015) QIUFANG OUYANG et al.   Molecular Medicine Reports

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

(2015) María Soler Artigas et al.   Nature Communications

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

(2015) Louise V Wain et al.   Lancet Respiratory Medicine

APOε4 is associated with enhanced in vivo innate immune responses in human subjects

(2014) Stephen C. Gale et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Apolipoprotein E-Deficient Mice Are Susceptible to the Development of Acute Lung Injury

(2014) Cory M. Yamashita et al.   RESPIRATION

Age, Gender, and Cancer but Not Neurodegenerative and Cardiovascular Diseases Strongly Modulate Systemic Effect of the Apolipoprotein E4 Allele on Lifespan

(2014) Alexander M. Kulminski et al.   PLoS Genetics

The role of lipid-related genes, aging-related processes, and environment in healthspan

(2013) Alexander M. Kulminski et al.   AGING CELL

Dysanaptic growth of lung and airway in children with post-infectious bronchiolitis obliterans

(2013) Ricardo A. Mosquera et al.   Clinical Respiratory Journal

Genome-wide association study of lung function phenotypes in a founder population

(2013) Tsung-Chieh Yao et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Activation of the TLR4 signaling pathway and abnormal cholesterol efflux lead to emphysema in ApoE-deficient mice

(2012) Monica Goldklang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Multi-ethnic reference values for spirometry for the 3–95-yr age range: the global lung function 2012 equations

(2012) Philip H. Quanjer et al.   EUROPEAN RESPIRATORY JOURNAL

Apolipoproteins and Apolipoprotein Mimetic Peptides Modulate Phagocyte Trafficking through Chemotactic Activity

(2012) Jennifer H. Madenspacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apolipoprotein E and familial longevity

(2012) Nicole Schupf et al.   NEUROBIOLOGY OF AGING

Paigen Diet–Fed Apolipoprotein E Knockout Mice Develop Severe Pulmonary Hypertension in an Interleukin-1–Dependent Manner

(2011) Allan Lawrie et al.   AMERICAN JOURNAL OF PATHOLOGY

Apolipoprotein E and Peptide Mimetics Modulate Inflammation by Binding the SET Protein and Activating Protein Phosphatase 2A

(2011) D. J. Christensen et al.   JOURNAL OF IMMUNOLOGY

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

(2011) María Soler Artigas et al.   NATURE GENETICS

Developmental Alveologenesis: New Roles for ApoE and LDL Receptor

(2011) Donald Massaro et al.   PEDIATRIC RESEARCH

ApoE-Deficient Mice on Cholate-Containing High-Fat Diet Reveal a Pathology Similar to Lung Sarcoidosis

(2010) Andriy O. Samokhin et al.   AMERICAN JOURNAL OF PATHOLOGY

Apolipoprotein E Negatively Regulates House Dust Mite–induced Asthma via a Low-Density Lipoprotein Receptor–mediated Pathway

(2010) Xianglan Yao et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Emphysema is associated with increased inflammation in lungs of atherosclerosis-prone mice by cigarette smoke: implications in comorbidities of COPD

(2010) Gnanapragasam Arunachalam et al.   Journal of Inflammation-London

“Predicting” parental longevity from offspring endophenotypes: Data from the Long Life Family Study (LLFS)

(2010) Anatoli I. Yashin et al.   MECHANISMS OF AGEING AND DEVELOPMENT

A Family Longevity Selection Score: Ranking Sibships by Their Longevity, Size, and Availability for Study

(2009) Paola Sebastiani et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

High-fat diet induces lung remodeling in ApoE-deficient mice: an association with an increase in circulatory and lung inflammatory factors

(2009) Amarjit S Naura et al.   LABORATORY INVESTIGATION

Genome-wide association study identifies five loci associated with lung function

(2009) Emmanouela Repapi et al.   NATURE GENETICS

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

(2009) Dana B Hancock et al.   NATURE GENETICS

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice

(2009) Nicklas Jacobsen et al.   Particle and Fibre Toxicology

Evolution of the human lifespan and diseases of aging: Roles of infection, inflammation, and nutrition

(2009) C. E. Finch   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Genome-Wide Association Study of Pulmonary Function Measures in the Framingham Heart Study

(2009) Jemma B. Wilk et al.   PLoS Genetics

Apoetm1Unc mice have impaired alveologenesis, low lung function, and rapid loss of lung function

(2008) Donald Massaro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

An antiproliferative BMP-2/PPARγ/apoE axis in human and murine SMCs and its role in pulmonary hypertension

(2008) Georg Hansmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Infection induces a positive acute phase apolipoprotein E response from a negative acute phase gene: role of hepatic LDL receptors

(2008) Li Li et al.   JOURNAL OF LIPID RESEARCH

Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS

(2008) Robert W. Mahley et al.   JOURNAL OF LIPID RESEARCH

APOE-related mortality: Effect of dementia, cardiovascular disease and gender

(2008) Lina Rosvall et al.   NEUROBIOLOGY OF AGING

Apolipoprotein E4 enhances attachment of Chlamydophila (Chlamydia) pneumoniae elementary bodies to host cells

(2007) Hervé C. Gérard et al.   MICROBIAL PATHOGENESIS