Ginseng metabolite protopanaxadiol interferes with lipid metabolism and induces endoplasmic reticulum stress and p53 activation to promote cancer cell death

Lipid-dependent regulation of the unfolded protein response

(2015) Romain Volmer et al.   CURRENT OPINION IN CELL BIOLOGY

TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiol

(2015) Zhiyu Zhang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Protopanaxadiol, an Active Ginseng Metabolite, Significantly Enhances the Effects of Fluorouracil on Colon Cancer

(2015) Chong-Zhi Wang et al.   Nutrients

Activation of the endoplasmic reticulum unfolded protein response by lipid disequilibrium without disturbed proteostasis in vivo

(2014) N. S. Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anticancer compound Oplopantriol A kills cancer cells through inducing ER stress and BH3 proteins Bim and Noxa

(2014) H R Jin et al.   Cell Death & Disease

Compound K, a Ginsenoside Metabolite, Inhibits Colon Cancer Growth via Multiple Pathways Including p53-p21 Interactions

(2013) Zhiyu Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The antitumor natural compound falcarindiol promotes cancer cell death by inducing endoplasmic reticulum stress

(2012) H R Jin et al.   Cell Death & Disease

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Specific Killing of Rb Mutant Cancer Cells by Inactivating TSC2

(2010) Binghui Li et al.   CANCER CELL

Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53

(2010) Binghui Li et al.   CANCER LETTERS

Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways

(2010) L Zhang et al.   CELL DEATH AND DIFFERENTIATION