Silencing TNFα with lipidoid nanoparticles downregulates both TNFα and MCP-1 in an in vitro co-culture model of diabetic foot ulcers

Published 2016 View Full Article

Authors

Keywords

Diabetic foot ulcer, Chronic wound, Lipidoid nanoparticle, Lipid nanoparticle, siRNA delivery, Tumor necrosis factor α (TNFα), Monocyte chemotactant protein (MCP-1/CCL2), Wound co-culture

Journal

Acta Biomaterialia

Volume 32, Issue -, Pages 120-128

Publisher

Elsevier BV

Online

2015-12-17

DOI

10.1016/j.actbio.2015.12.023

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