Intracellular Signaling Mechanisms Involved in the Biological Effects of the Xanthophyll Carotenoid Astaxanthin to Prevent the Photo-aging of the Skin in a Reactive Oxygen Species Depletion-independent Manner: The Key Role of Mitogen and Stress-activated

The stem cell factor-stimulated melanogenesis in human melanocytes can be abrogated by interrupting the phosphorylation of MSK1: evidence for involvement of the p38/MSK1/CREB/MITF axis

(2018) Takao Niwano et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

The Inhibitory Effects of Anti-Oxidants on Ultraviolet-Induced Up-Regulation of the Wrinkling-Inducing Enzyme Neutral Endopeptidase in Human Fibroblasts

(2016) Hiroaki Nakajima et al.   PLoS One

UVB Stimulates the Expression of Endothelin B Receptor in Human Melanocytes via a Sequential Activation of the p38/MSK1/CREB/MITF Pathway Which Can Be Interrupted by a French Maritime Pine Bark Extract through a Direct Inactivation of MSK1

(2015) Hideki Tagashira et al.   PLoS One

The UVB-Stimulated Expression of Transglutaminase 1 Is Mediated Predominantly via the NFκB Signaling Pathway: New Evidence of Its Significant Attenuation through the Specific Interruption of the p38/MSK1/NFκBp65 Ser276 Axis

(2015) Shuko Terazawa et al.   PLoS One

Withaferin A abolishes the stem cell factor-stimulated pigmentation of human epidermal equivalents by interrupting the auto-phosphorylation of c-KIT in human melanocytes

(2014) Shuko Terazawa et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Inhibitors of Intracellular Signaling Pathways that Lead to Stimulated Epidermal Pigmentation: Perspective of Anti-Pigmenting Agents

(2014) Genji Imokawa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Key Role of CRF in the Skin Stress Response System

(2013) Andrzej T. Slominski et al.   ENDOCRINE REVIEWS

Abrogating effect of a xanthophyll carotenoid astaxanthin on the stem cell factor-induced stimulation of human epidermal pigmentation

(2012) Hiroaki Nakajima et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Astaxanthin attenuates the UVB-induced secretion of prostaglandin E2 and interleukin-8 in human keratinocytes by interrupting MSK1 phosphorylation in a ROS depletion-independent manner

(2012) Shuko Terazawa et al.   EXPERIMENTAL DERMATOLOGY

Regulation of melanocyte pivotal transcription factor MITF by some other transcription factors

(2011) Ping Wan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

L-tyrosine and L-dihydroxyphenylalanine as hormone-like regulators of melanocyte functions

(2011) Andrzej Slominski et al.   Pigment Cell & Melanoma Research

Down-regulation of IL-6 production by astaxanthin via ERK-, MSK-, and NF-κB-mediated signals in activated microglia

(2010) Yeon Hyang Kim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Astaxanthin Inhibits Glutamate Release in Rat Cerebral Cortex Nerve Terminals via Suppression of Voltage-Dependent Ca2+Entry and Mitogen-Activated Protein Kinase Signaling Pathway

(2010) Tzu Yu Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Tangeretin Reduces Ultraviolet B (UVB)-Induced Cyclooxygenase-2 Expression in Mouse Epidermal Cells by Blocking Mitogen-Activated Protein Kinase (MAPK) Activation and Reactive Oxygen Species (ROS) Generation

(2010) Ji Hye Yoon et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Homoisoflavanone inhibits UVB-induced skin inflammation through reduced cyclooxygenase-2 expression and NF-κB nuclear localization

(2010) Seulgi Hur et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

A single UVB exposure increases the expression of functional KIT in human melanocytes by up-regulating MITF expression through the phosphorylation of p38/CREB

(2009) Yuki Mizutani et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Ser276 Phosphorylation of NF-kB p65 by MSK1 Controls SCF Expression in Inflammation

(2009) Laurent Reber et al.   PLoS One

Hepatocyte Growth Factor Suppresses Proinflammatory NFκB Activation through GSK3β Inactivation in Renal Tubular Epithelial Cells

(2008) Rujun Gong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epistatic connections between microphthalmia-associated transcription factor and endothelin signaling in Waardenburg syndrome and other pigmentary disorders

(2007) Kayo Sato-Jin et al.   FASEB JOURNAL