Article
Pediatrics
Dinesh Dharel, Nalini Singhal, Christel Wood, Zenon Cieslak, Fabiana Bacchini, Prakesh S. Shah, Xiang Y. Ye, Belal Alshaikh
Summary: Approximately two-thirds of infants born very preterm received mother's own milk at hospital discharge, with rates varying across neonatal intensive care units (NICUs). Supporting mothers to provide breast milk in the first 3 days after birth may be associated with improved mother's own milk feeding rates at discharge.
JOURNAL OF PEDIATRICS
(2021)
Article
Medicine, Research & Experimental
D. Mallardi, C. Tabasso, P. Piemontese, S. Morandi, T. Silvetti, F. Biscarini, P. Cremonesi, B. Castiglioni, V Pica, M. Stuknyte, I De Noni, O. Amato, N. Liotto, F. Mosca, P. Roggero
Summary: The study showed that inoculating PDHM with mother's own milk could restore bacterial growth and personalize the human milk microbiome in PDHM. This personalized effect is beneficial due to the presence of maternal probiotic bacteria in the milk, making PDHM more similar to the mother's own milk.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Pediatrics
Yiming Zhu, Xiaohui Chen, Jingai Zhu, Chengyao Jiang, Zhangbin Yu, Ailing Su
Summary: Early initiation and continued mother's own milk feeding during hospitalization can reduce the risk of moderate and severe bronchopulmonary dysplasia (BPD) in infants with very low birth weight (VLBW).
FRONTIERS IN PEDIATRICS
(2022)
Article
Obstetrics & Gynecology
Anita Esquerra-Zwiers, Michael E. Schoeny, Janet Engstrom, Jennifer Wicks, Jennifer Szotek, Paula Meier, Aloka L. Patel
Summary: This study compared differences in mother's own milk provision and enteral feeding outcomes, as well as differences in preterm formula and donor human milk use in preterm infants. The researchers found that the availability of donor human milk may have varying effects on mother's own milk provision among different racial/ethnic groups.
BREASTFEEDING MEDICINE
(2021)
Article
Nursing
Rebecca Hoban, Hadar Nir, Emily Somerset, Jordan Lewis, Sharon Unger, Deborah L. O'Connor
Summary: This study investigated the cytokines and inflammatory markers in the breastmilk of parents of very preterm infants, as well as their correlations with infant's stool calprotectin. The results showed detectable inflammatory markers in the breastmilk, some of which changed over time, but no correlation was found with infant's stool calprotectin.
JOURNAL OF HUMAN LACTATION
(2023)
Article
Nutrition & Dietetics
Noa Ofek Shlomai, Yonatan Shneor Patt, Yaara Wazana, Tomer Ziv-Baran, Tzipora Strauss, Iris Morag
Summary: This study compared the effects of exclusive breastmilk, mixed feeding, and exclusive formula feeding on preterm infants. The results showed that exclusive formula feeding was not associated with an increased risk of any adverse outcomes in the absence of own mother's breastmilk. Clinicians should take this finding into consideration when deciding on feeding options.
Article
Nutrition & Dietetics
Reka A. Vass, Gabriella Kiss, Edward F. Bell, Robert D. Roghair, Attila Miseta, Jozsef Bodis, Simone Funke, Tibor Ertl
Summary: Pituitary hormones like prolactin and luteinizing hormone were found to be higher in breast milk from mothers of preterm infants compared to term infants. Infant formulas have higher total protein content but do not contain detectable levels of pituitary hormones.
Article
Obstetrics & Gynecology
Deesha D. Mago-Shah, Kamlesh Athavale, Kimberley Fisher, Elizabeth Heyward, David Tanaka, C. Michael Cotten
Summary: This study aimed to identify the daily pumping frequencies associated with producing more than 500 milliliters of milk per day by postnatal day 14 (CTV) for mothers of infants in the NICU. Demographics and daily pumping frequencies were compared between mothers who did and did not experience CTV. The results showed associations between race, insurance, delivery type, birthweight, and CTV. For mothers who experienced CTV, there was a steady increase in average pumping episodes, stabilizing at 5 pumping episodes per day by postnatal day 5 (5 x 5). These mothers were also more likely to pump between 0100 and 0500 (AM pumping). Birthweight, 5 x 5, and AM pumping were independently associated with CTV in multivariable analysis. Supporting NICU mothers to achieve 5 or more daily pumping sessions by postnatal day 5 could improve the likelihood of achieving CTV.
JOURNAL OF PERINATOLOGY
(2023)
Review
Pediatrics
Natalie A. Strobel, Claire Adams, Daniel R. McAullay, Karen M. Edmond
Summary: In preterm and low birth weight infants, feeding with infant formula compared with mother's own milk has little effect on mortality, infection, growth, or neurodevelopment, but increases the risk of developing necrotizing enterocolitis.
Article
Medicine, General & Internal
Teresa Janevic, Kimberly B. Glazer, Luciana Vieira, Ellerie Weber, Joanne Stone, Toni Stern, Angela Bianco, Brian Wagner, Siobhan M. Dolan, Elizabeth A. Howell
Summary: This study found no evidence for increased racial/ethnic disparities in preterm birth in New York City during the early stages of the COVID-19 pandemic, regardless of whether women tested positive or negative for SARS-CoV-2.
Article
Nutrition & Dietetics
Jing Huang, Zhi Zheng, Xiao-yan Zhao, Li-han Huang, Lian Wang, Xiao-lan Zhang, Xin-zhu Lin
Summary: Feeding preterm infants with fresh mother's own milk (MOM) can protect them from complications and improve their outcomes. Compared to pasteurized MOM, feeding fresh MOM leads to a higher survival rate, lower incidence of bronchopulmonary dysplasia, and better feeding and growth outcomes.
MATERNAL AND CHILD NUTRITION
(2023)
Article
Pediatrics
Veronique Demers-Mathieu, Robert K. Huston, Andi M. Markell, Elizabeth A. McCulley, Rachel L. Martin, David C. Dallas
Summary: The study found that pertussis-specific antibodies in mother's breast milk remained stable during infant digestion, while anti-pertussis IgA and IgG from donor breast milk decreased in gastric contents. The constant and variable regions of antibodies, along with maternal immunization, appear to be critical for their stability to proteolytic digestion and pasteurization.
PEDIATRIC RESEARCH
(2021)
Article
Multidisciplinary Sciences
Li-Lian Chen, Jie Liu, Xiao-He Mu, Xi-Yang Zhang, Chuan-Zhong Yang, Xiao-Yun Xiong, Mei-Qi Wang
Summary: The aim of this study was to investigate the impact of oropharyngeal mother's milk administration on salivary secretory immunoglobulin A (sIgA) levels in preterm infants fed by gastric tube. The results showed that oropharyngeal mother's milk administration can improve the salivary sIgA levels of preterm infants.
SCIENTIFIC REPORTS
(2022)
Article
Obstetrics & Gynecology
Gregory Valentine, Steven Ford, Joseph Hagan, Heeju Yang, Jeffery Chen, Nancy Hurst, Kjersti Aagaard, Amy Hair
Summary: The study suggests that promoting mother's own milk consumption in the first 2-4 weeks is crucial for achieving exclusive mother's own milk feeding at discharge, with minimal impact of increasing mother's own milk consumption after 28 days.
JOURNAL OF PERINATOLOGY
(2021)
Article
Microbiology
Monica F. Torrez Lamberti, Natalie A. Harrison, Marion M. Bendixen, Evon M. DeBose-Scarlett, Sharon C. Thompson, Josef Neu, Leslie Ann Parker, Graciela L. Lorca
Summary: The study aimed to determine whether FMOM can be used to personalize DHM and found that FMOM can achieve a similar microbial composition to MOM, making it a feasible option in a milk restoration strategy.
FRONTIERS IN MICROBIOLOGY
(2021)
Review
Obstetrics & Gynecology
Clarisa Poeliniz, Janet L. Engstrom, Rebecca Hoban, Aloka L. Patel, Paula Meier
BREASTFEEDING MEDICINE
(2020)
Article
Pediatrics
Tricia J. Johnson, Andrew Berenz, Jennifer Wicks, Anita Esquerra-Zwiers, Kelly S. Sulo, Megan E. Gross, Jennifer Szotek, Paula Meier, Aloka L. Patel
JOURNAL OF PEDIATRICS
(2020)
Article
Pediatrics
Yanqi Li, Rene Liang Shen, Adejumoke Ayede, Janet Berrington, Frank H. Bloomfield, Olubunmi O. Busari, Barbara E. Cormack, Nicholas D. Embleton, Johannes B. van Goudoever, Gorm Greisen, Zhongqian He, Yan Huang, Xiaodong Li, Hung-Chih Lin, Jiaping Mei, Paula P. Meier, Chuan Nie, Aloka L. Patel, Per T. Sangild, Thomas Skeath, Karen Simmer, Signe Uhlenfeldt, Marita de Waard, Sufen Ye, Xuqiang Ye, Chunyi Zhang, Yanna Zhu, Ping Zhou
JOURNAL OF PEDIATRICS
(2020)
Article
Pediatrics
Rebecca Hoban, Clarisa Medina Poeliniz, Emily Somerset, Ching Tat Lai, Judy Janes, Aloka L. Patel, Donna Geddes, Paula P. Meier
Summary: In breast pump-dependent mothers of preterm infants, the concentrations of sodium and Na:K ratio in the milk were associated with milk volume production on postpartum day 14. These biomarkers may serve as objective measures to detect modifiable lactation problems in a high-risk population.
JOURNAL OF PEDIATRICS
(2021)
Correction
Obstetrics & Gynecology
Kousiki Patra, Michelle M. Greene, Grace Tobin, Gina Casini, Anita L. Esquerra-Zwiers, Paula P. Meier, Aloka L. Patel
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Kousiki Patra, Michelle M. Greene, Grace Tobin, Gina Casini, Anita L. Esquerra-Zwiers, Paula P. Meier, Aloka L. Patel
Summary: The study aimed to evaluate the impact of donor milk on neurodevelopmental outcome in VLBW infants. Results showed no differences in neurodevelopmental outcome between infants who received donor milk and those who did not, possibly due to similar intake of mother's own milk at different time points.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Anita Esquerra-Zwiers, Michael E. Schoeny, Janet Engstrom, Jennifer Wicks, Jennifer Szotek, Paula Meier, Aloka L. Patel
Summary: This study compared differences in mother's own milk provision and enteral feeding outcomes, as well as differences in preterm formula and donor human milk use in preterm infants. The researchers found that the availability of donor human milk may have varying effects on mother's own milk provision among different racial/ethnic groups.
BREASTFEEDING MEDICINE
(2021)
Article
Nutrition & Dietetics
Meghan B. Azad, Nathan C. Nickel, Lars Bode, Meredith Brockway, Amy Brown, Christina Chambers, Camie Goldhammer, Katie Hinde, Michelle McGuire, Daniel Munblit, Aloka L. Patel, Rafael Perez-Escamilla, Kathleen M. Rasmussen, Natalie Shenker, Bridget E. Young, Luisa Zuccolo
Summary: This paper summarizes a workshop that focused on breastfeeding and human milk research, identifying key research areas, barriers, and proposing an action plan. Priority research areas include increasing breastfeeding rates, raising awareness of benefits, studying different modes of milk feeding, and understanding the health effects of breastfeeding.
MATERNAL AND CHILD NUTRITION
(2021)
Review
Obstetrics & Gynecology
Rebecca Hoban, Rakhee M. Bowker, Megan E. Gross, Aloka L. Patel
Summary: Breastfeeding is crucial for the health of premature infants in the NICU, but there are significant racial and economic disparities in breast milk provision that need to be addressed. Helping mothers improve breastfeeding skills and providing support is essential.
SEMINARS IN PERINATOLOGY
(2021)
Article
Pediatrics
Brandy L. Frost, Aloka L. Patel, Daniel T. Robinson, Carol Lynn Berseth, Timothy Cooper, Michael Caplan
Summary: The study examined the feasibility of providing a concentrated emulsified long-chain polyunsaturated fatty acids (LCPUFA) supplement to very low birth weight infants and evaluated the effect on blood LCPUFA concentrations. Results indicated that supplementation with 360 mg of combined DHA and ARA significantly increased blood levels of DHA and ARA in the first 8 weeks of life.
JOURNAL OF PEDIATRICS
(2021)
Article
Nutrition & Dietetics
Alexis Artman, Annie Huang, Rakhee Bowker, Leah Cerwinske, Shaun Cooper, Tricia Johnson, Aloka L. Patel
Summary: The study found a significant association between maternal age, gestational age, infant birth weight, and race/ethnicity with the receipt of adjusted vitamin D dose for VLBW and very preterm infants, but no significant associations were found between health indicators and vitamin D dose.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2022)
Article
Pediatrics
Tricia J. Johnson, Paula P. Meier, Michael E. Schoeny, Amelia Bucek, Judy E. Janes, Jesse J. Kwiek, John A. F. Zupancic, Sarah A. Keim, Aloka L. Patel
Summary: This study aims to test the effectiveness and cost-effectiveness of an intervention that offsets the costs of pumping breast milk for Black very low birth weight and very preterm infants, in order to increase the likelihood of receiving mother's own milk at the time of discharge.
Article
Obstetrics & Gynecology
Clarisa Medina Poeliniz, Rebecca Hoban, Michael E. Schoeny, Janet L. Engstrom, Aloka L. Patel, Paula Meier
Summary: There is limited knowledge about secretory activation in overweight and obese mothers who are breast pump dependent with a premature infant in the neonatal intensive care unit. Research suggests that there is delayed or impaired SA in this population, with the window of opportunity for research and clinical interventions being the first 1-7 days postpartum.
BREASTFEEDING MEDICINE
(2022)
Article
Economics
Tricia J. Johnson, Aloka L. Patel, Michael E. Schoeny, Paula P. Meier
Summary: This study aimed to determine the relationship between hospitalization costs and mother's own milk (MOM) dose for very low birth weight infants and quantify the incremental cost of complications that can be prevented with MOM intake. The results showed that reducing preventable complications through MOM intake has significant cost implications.
PHARMACOECONOMICS-OPEN
(2022)
Review
Pediatrics
Aloka L. Patel, Tricia J. Johnson, Paula P. Meier
Summary: VLBW infants are more likely to be born to black mothers, who are less likely to provide MOM due to economic factors and family responsibilities. The lack of MOM leads to high costs associated with substitutes, exacerbating the disparities faced by black mothers.
PEDIATRIC RESEARCH
(2021)