Article
Pediatrics
Silvia L. Verhofste, Amy L. Conrad, Rebecca J. Johnson, Emily J. Steinbach, Janice M. Staber, Lyndsay A. Harshman
Summary: This study examined the self-concept of children with CKD and its influence on academic achievement. The findings showed that despite having a chronic disease, children with CKD have a positive self-concept, which may predict their academic success.
PEDIATRIC NEPHROLOGY
(2023)
Article
Pediatrics
Siah Kim, Anita Van Zwieten, Jennifer Lorenzo, Rabia Khalid, Suncica Lah, Kerry Chen, Madeleine Didsbury, Anna Francis, Steven Mctaggart, Amanda Walker, Fiona E. Mackie, Chanel Prestidge, Armando Teixeira-Pinto, Allison Tong, Katrina Blazek, Belinda Barton, Jonathan C. Craig, Germaine Wong
Summary: Children with chronic kidney disease (CKD) have cognitive and academic challenges, especially those undergoing kidney replacement therapy (KRT). Regardless of CKD stage, academic performance declines as children grow older.
PEDIATRIC NEPHROLOGY
(2022)
Review
Nutrition & Dietetics
Adriana Mocanu, Roxana Alexandra Bogos, Tudor Ilie Lazaruc, Laura Mihaela Trandafir, Vasile Valeriu Lupu, Ileana Ioniuc, Mirabela Alecsa, Anca Ivanov, Ancuta Lupu, Iuliana Magdalena Starcea
Summary: The human intestinal microbiota plays a crucial role in promoting health and preventing disease. It is influenced by factors such as diet, genetics, and environment. In pediatric patients, the gut microbiota is vulnerable to disruption and has been linked to chronic kidney disease.
Article
Medicine, Research & Experimental
Miguel A. Villasis-Keever, Jessie N. Zurita-Cruz, Juana Serret-Montoya, Andrea Ponce de Leon-Herrera, Penelope Galvan-Heredia, Claudia del Carmen Zepeda-Martinez, Gabriela Alegria-Torres, Carolina Hernandez-Hernandez, Sara Alonso-Flores, Lourdes Barbosa-Cortes, Luis Antonio Arenas-Aguayo
Summary: Although the frequency of cardiometabolic factors in patients with chronic diseases is lower than in obese and overweight children, hypertriglyceridemia, hypoalphalipoproteinemia, and systemic arterial hypertension are still common.
ARCHIVES OF MEDICAL RESEARCH
(2021)
Article
Neurosciences
Peter J. Duquette, Debbie S. Gipson, Stephen R. Hooper
Summary: Children with chronic kidney disease may have specific deficits in multiple attention dimensions, particularly for those with more severe disease.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Review
Biology
Lavinia Capossela, Serena Ferretti, Silvia D'Alonzo, Lorenzo Di Sarno, Valeria Pansini, Antonietta Curatola, Antonio Chiaretti, Antonio Gatto
Summary: Mineral and bone disorder (MBD) is common in pediatric patients with chronic kidney disease (CKD) and leads to disorders in bone remodeling. However, the lack of bone biopsy data and validated methods to evaluate bone morphology in children has made it challenging to effectively assess renal osteodystrophy in pediatric CKD. This review aims to explore the pathogenesis, diagnosis, and treatment of CKD-MBD in children and the effects of renal osteodystrophy on the growing skeleton.
Article
Pediatrics
Katherine L. Kurzinski, Yunwen Xu, Derek K. Ng, Susan L. Furth, George J. Schwartz, Bradley A. Warady
Summary: This study aimed to evaluate the prevalence and risk factors for hyperkalemia in pediatric chronic kidney disease (CKD). The study found that hyperkalemia was more common in children with advanced stage CKD, glomerular disease, low -CO2, and the use of ACEi/ARB therapy. These findings can help clinicians identify high-risk patients and initiate potassium-lowering therapy earlier.
PEDIATRIC NEPHROLOGY
(2023)
Review
Oncology
Kim T. Vuong, Catherine Joseph, Joseph R. Angelo
Summary: While AKI after HCT is well-described in pediatric patients, limited literature exists regarding the long-term renal consequences, development of CKD, and CKD care in these patients. CKD affects almost 50% of patients after HCT with various causes, and as renal function declines, mortality increases. This review aims to summarize definitions, etiologies, and management strategies for AKI and CKD post-HCT, with a focus on early identification, intervention, and discussion of ESKD and renal transplant.
FRONTIERS IN ONCOLOGY
(2023)
Article
Urology & Nephrology
Rebecca M. Lombel, Paul R. Brakeman, Bryan S. Sack, Lavjay Butani
Summary: The causes of pediatric ESRD are different from those in adults, with congenital anomalies of the kidney and urinary tract being the most common. These structural abnormalities require coordinated care with pediatric urology teams. Pediatric nephrologists and urologists often encounter cases such as antenatal hydronephrosis, obstructive uropathies, and vesicoureteral reflux.
ADVANCES IN CHRONIC KIDNEY DISEASE
(2022)
Article
Endocrinology & Metabolism
Miguel Angel Villasis-Keever, Jessie Nallely Zurita-Cruz, Claudia Zepeda-Martinez, Gabriela Alegria-Torres, Juana Serret-Montoya, Maria de Jesus Estrada-Loza, Beatriz Carolina Hernandez-Hernandez, Sara Alonso-Flores, Monica Zavala-Serret
Summary: The study found that adipokines may have an impact on cardiac function in children undergoing kidney replacement therapy, especially in the long term. Free leptin, leptin, and left ventricular ejection fraction (LVEF) at the beginning of follow-up were associated with the decrease in LVEF at the 24-month follow-up.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Wei-Ting Liao, Wei-Ling Chen, You-Lin Tain, Chien-Ning Hsu
Summary: Cardiovascular disease is the leading cause of death among patients with chronic kidney disease, including both adults and children. Hypertension is one of the risk factors for cardiovascular disease. Monitoring blood pressure, cardiac sonography, and assessing arterial stiffness can help detect subclinical cardiovascular disease in pediatric chronic kidney disease patients. Congenital anomalies of the kidney and urinary tract are the main causes of pediatric chronic kidney disease. Complement factor H and related proteins are associated with cardiovascular disease risk in children with chronic kidney disease.
Article
Medicine, General & Internal
Na Ri Kang, Yo Han Ahn, Eujin Park, Keum Hwa Lee, Hee Sun Baek, Seong Heon Kim, Heeyeon Cho, Min Hyun Cho, Jae Il Shin, Joo Hoon Lee, Hae Il Cheong, Hee Gyung Kang, Young Seo Park, Il-Soo Ha, Duk-Soo Moon, Kyoung Hee Han
Summary: This study investigated the intelligence levels and risk factors for low intelligence in children and adolescents with CKD, finding that participants with short stature, failure to thrive, more severe CKD stage, longer duration of CKD, and those who were Medicare or Medicaid beneficiaries had significantly lower intelligence levels. The association between intelligence and longer duration of CKD and growth failure remained significant after controlling for demographic and clinical variables, highlighting the importance of early interventions such as kidney transplantation.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2021)
Review
Pediatrics
Andrea Grund, Manish D. Sinha, Dieter Haffner, Maren Leifheit-Nestler
Summary: FGF23 is a key factor in the development of cardiovascular risk factors in pediatric CKD patients, with limited data on its prevalence and determinants in this population. Current research mainly focuses on the impact of FGF23 in adult CKD, and further investigation is needed for pediatric CKD patients.
FRONTIERS IN PEDIATRICS
(2021)
Article
Psychology, Multidisciplinary
Jesus Alfonso D. Datu, Weipeng Yang
Summary: Academic buoyancy refers to students' ability to deal with obstacles in school contexts and has been found to be related to academic motivational dimensions and achievement. This study shows that academic buoyancy has indirect effects on achievement through autonomous motivation, highlighting the importance of cultivating students' capability to handle daily academic challenges for academic success.
CURRENT PSYCHOLOGY
(2021)
Article
Genetics & Heredity
Xiaoyuan Wang, Huijie Xiao, Yong Yao, Ke Xu, Xiaoyu Liu, Baige Su, Hongwen Zhang, Na Guan, Xuhui Zhong, Yanqin Zhang, Jie Ding, Fang Wang
Summary: In Chinese children, the common causative genes for non-glomerular renal dysfunction caused by renal hypodysplasia and cystic kidney diseases vary with age and CKD stage at disease onset. These findings have the potential to improve management and genetic counseling of these diseases in clinical practice.
FRONTIERS IN GENETICS
(2021)