Verapamil Attenuated Prediabetic Neuropathy in High-Fat Diet-Fed Mice through Inhibiting TXNIP-Mediated Apoptosis and Inflammation

MiR-34a Regulates Axonal Growth of Dorsal Root Ganglia Neurons by Targeting FOXP2 and VAT1 in Postnatal and Adult Mouse

(2018) Longfei Jia et al.   MOLECULAR NEUROBIOLOGY

Verapamil and beta cell function in adults with recent-onset type 1 diabetes

(2018) Fernando Ovalle et al.   NATURE MEDICINE

Thioredoxin interacting protein mediates lipid-induced impairment of glucose uptake in skeletal muscle

(2016) Ashok Mandala et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Diabetic Neuropathy: A Position Statement by the American Diabetes Association

(2016) Rodica Pop-Busui et al.   DIABETES CARE

Single nucleotide polymorphisms in the Trx2/TXNIP and TrxR2 genes of the mitochondrial thioredoxin antioxidant system and the risk of diabetic retinopathy in patients with Type 2 diabetes mellitus

(2016) Sara Mankoc Ramus et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats

(2016) Chunchun Ding et al.   Scientific Reports

Thioredoxin interacting protein (TXNIP) regulates tubular autophagy and mitophagy in diabetic nephropathy through the mTOR signaling pathway

(2016) Chunling Huang et al.   Scientific Reports

Thioredoxin-Interacting Protein Deficiency Protects against Diabetic Nephropathy

(2015) A. Shah et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Thioredoxin-interacting protein mediates NALP3 inflammasome activation in podocytes during diabetic nephropathy

(2014) Pan Gao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Diabetic Neuropathy: Mechanisms, Emerging Treatments, and Subtypes

(2014) James W. Albers et al.   Current Neurology and Neuroscience Reports

Effect of High-Fat Diet on Peripheral Neuropathy in C57BL/6 Mice

(2014) Lingling Xu et al.   International Journal of Endocrinology

Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet

(2013) Islam N. Mohamed et al.   DIABETOLOGIA

Exercise and DHA Prevent the Negative Effects of Hypoxia on EEG and Nerve Conduction Velocity

(2013) Haydar Ali Erken et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

ChREBP in NASH – A liver transcription factor comes in from the cold

(2013) Michael R. Charlton   JOURNAL OF HEPATOLOGY

TXNIP shuttling: missing link between oxidative stress and inflammasome activation

(2013) Troy Lane et al.   Frontiers in Physiology

Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

(2012) Christine M. Oslowski et al.   Cell Metabolism

Preventing  -Cell Loss and Diabetes With Calcium Channel Blockers

(2012) G. Xu et al.   DIABETES

Glucose sensing by ChREBP/MondoA–Mlx transcription factors

(2012) Essi Havula et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Thioredoxin Interacting Protein: Redox Dependent and Independent Regulatory Mechanisms

(2011) Oded N. Spindel et al.   ANTIOXIDANTS & REDOX SIGNALING

Metformin mitigates the impaired development of skeletal muscle in the offspring of obese mice

(2011) J F Tong et al.   Nutrition & Diabetes

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy

(2010) L Perrone et al.   Cell Death & Disease

Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein

(2009) Junqin Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Elevated Triglycerides Correlate With Progression of Diabetic Neuropathy

(2009) T. D. Wiggin et al.   DIABETES

Dyslipidemia-Induced Neuropathy in Mice: The Role of oxLDL/LOX-1

(2009) A. M. Vincent et al.   DIABETES

Pro-Inflammatory Mechanisms in Diabetic Neuropathy: Focus on the Nuclear Factor Kappa B Pathway

(2008) Norman Cameron et al.   CURRENT DRUG TARGETS

Thioredoxin-Interacting Protein: A Critical Link Between Glucose Toxicity and  -Cell Apoptosis

(2008) J. Chen et al.   DIABETES

Carboxypeptidase E mediates palmitate-induced  -cell ER stress and apoptosis

(2008) K. D. Jeffrey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA