Nicotine and Cotinine Inhibit Catalase and Glutathione Reductase Activity Contributing to the Impaired Osteogenesis of SCP-1 Cells Exposed to Cigarette Smoke

Nicotine induces apoptosis in human osteoblasts via a novel mechanism driven by H 2 O 2 and entailing Glyoxalase 1-dependent MG-H1 accumulation leading to TG2-mediated NF-kB desensitization: Implication for smokers-related osteoporosis

(2018) Lorella Marinucci et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of Nrf2 by MIND4-17 protects osteoblasts from hydrogen peroxide-induced oxidative stress

(2017) Shiguang Guo et al.   Oncotarget

Extremely low frequency pulsed electromagnetic fields cause antioxidative defense mechanisms in human osteoblasts via induction of •O2 − and H2O2

(2017) Sabrina Ehnert et al.   Scientific Reports

N-acetyl cysteine inhibits H2O2-mediated reduction in the mineralization of MC3T3-E1 cells by down-regulating Nrf2/HO-1 pathway

(2015) Daewoo Lee et al.   BMB Reports

Deletion of Nrf2 reduces skeletal mechanical properties and decreases load-driven bone formation

(2015) Yong-Xin Sun et al.   BONE

Factors circulating in the blood of type 2 diabetes mellitus patients affect osteoblast maturation – Description of a novel in vitro model

(2015) Sabrina Ehnert et al.   EXPERIMENTAL CELL RESEARCH

p38 MAPK-dependent Nrf2 induction enhances the resistance of glioma cells against TMZ

(2015) Leina Ma et al.   MEDICAL ONCOLOGY

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

N-acetyl cysteine as an osteogenesis-enhancing molecule for bone regeneration

(2013) Masahiro Yamada et al.   BIOMATERIALS

Transforming growth factor β1 inhibits bone morphogenic protein (BMP)-2 and BMP-7 signaling via upregulation of Ski-related novel protein N (SnoN): possible mechanism for the failure of BMP therapy?

(2012) Sabrina Ehnert et al.   BMC Medicine

Role of GSH/GSSG redox couple in osteogenic activity and osteoclastogenic markers of human osteoblast-like SaOS-2 cells

(2012) Cecilia Romagnoli et al.   FEBS Journal

N-acetyl-L-cysteine enhances the osteogenic differentiation and inhibits the adipogenic differentiation through up regulation of Wnt 5a and down regulation of PPARG in bone marrow stromal cells

(2011) HuiJiao Ji et al.   BIOMEDICINE & PHARMACOTHERAPY

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

(2011) Balaraman Kalyanaraman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Proteasome Inhibition Induces a p38 MAPK Pathway-Dependent Antiapoptotic Program via Nrf2 in Thyroid Cancer Cells

(2011) Zhen-Xian Du et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effects of nicotine on proliferation and osteoblast differentiation in human alveolar bone marrow-derived mesenchymal stem cells

(2011) Beom-Su Kim et al.   LIFE SCIENCES

Toxic elements in tobacco and in cigarette smoke: inflammation and sensitization

(2011) R. Steve Pappas   Metallomics

Quercetin Protects Primary Human Osteoblasts Exposed to Cigarette Smoke through Activation of the Antioxidative Enzymes HO-1 and SOD-1

(2011) Karl F. Braun et al.   TheScientificWorldJOURNAL

The Role of Primary Cilia in Mesenchymal Stem Cell Differentiation: A Pivotal Switch in Guiding Lineage Commitment

(2010) Padmaja Tummala et al.   Cellular and Molecular Bioengineering

TGF-β1 As Possible Link between Loss of Bone Mineral Density and Chronic Inflammation

(2010) Sabrina Ehnert et al.   PLoS One

Deletion ofKeap1in the Lung Attenuates Acute Cigarette Smoke–Induced Oxidative Stress and Inflammation

(2009) David J. Blake et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotine modulates bone metabolism-associated gene expression in osteoblast cells

(2009) David E. Rothem et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue

(2009) Christine J Weydert et al.   Nature Protocols

Oxidative Stress Induces Vascular Calcification through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling

(2008) Chang Hyun Byon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Introducing a single-cell-derived human mesenchymal stem cell line expressing hTERT after lentiviral gene transfer

(2008) Wolfgang Böcker et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Protective effects of mate tea (Ilex paraguariensis) on H2O2-induced DNA damage and DNA repair in mice

(2008) D. D. C. Miranda et al.   MUTAGENESIS

Coordinated Changes of Mitochondrial Biogenesis and Antioxidant Enzymes During Osteogenic Differentiation of Human Mesenchymal Stem Cells

(2008) Chien-Tsun Chen et al.   STEM CELLS

Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells

(2007) Aruna Kode et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

N-acetylcysteine stimulates osteoblastic differentiation of mouse calvarial cells

(2007) Ji Hae Jun et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults

(2007) W OSBURN et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH