Antioxidant Activity Mediates Pirfenidone Antifibrotic Effects in Human Pulmonary Vascular Smooth Muscle Cells Exposed to Sera of Idiopathic Pulmonary Fibrosis Patients

Pirfenidone protects against paraquat-induced lung injury and fibrosis in mice by modulation of inflammation, oxidative stress, and gene expression

(2018) Fateme Pourgholamhossein et al.   FOOD AND CHEMICAL TOXICOLOGY

miR-26b-5p regulates hypoxia-induced phenotypic switching of vascular smooth muscle cells via the TGF-β/Smad4 signaling pathway

(2017) Changwu Ruan et al.   Molecular Medicine Reports

Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells

(2017) Anna Maria Posadino et al.   TOXICOLOGY IN VITRO

Efficacy and Safety of Nintedanib for the Treatment of Idiopathic Pulmonary Fibrosis: An Update

(2017) José Antonio Rodríguez-Portal   Drugs in research & development

Pirfenidone attenuates bleomycin-induced pulmonary fibrosis in mice by regulating Nrf2/Bach1 equilibrium

(2017) Yuan Liu et al.   BMC Pulmonary Medicine

Idiopathic pulmonary fibrosis

(2017) Fernando J. Martinez et al.   Nature Reviews Disease Primers

Rock Activation in Lung of Idiopathic Pulmonary Fibrosis with Oxidative Stress

(2017) Y. Shimizu et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Vascular Smooth Muscle Cells in Atherosclerosis

(2016) Martin R. Bennett et al.   CIRCULATION RESEARCH

Plasma protein thiols: an early marker of oxidative stress in asthma and chronic obstructive pulmonary disease

(2016) Angelo Zinellu et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

(2015) Sebastian Altenhöfer et al.   ANTIOXIDANTS & REDOX SIGNALING

Gestational Diabetes Mellitus Impairs Fetal Endothelial Cell Functions Through a Mechanism Involving MicroRNA-101 and Histone Methyltransferase Enhancer of Zester Homolog-2Significance

(2015) Ilaria Floris et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The 2015 guidelines for idiopathic pulmonary fibrosis: an important chapter in the evolution of the management of patients with IPF: TABLE 1

(2015) Kevin C. Wilson et al.   EUROPEAN RESPIRATORY JOURNAL

Resveratrol alters human endothelial cells redox state and causes mitochondrial-dependent cell death

(2015) Anna Maria Posadino et al.   FOOD AND CHEMICAL TOXICOLOGY

Change in serum marker of oxidative stress in the progression of idiopathic pulmonary fibrosis

(2015) Yasuo Matsuzawa et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension

(2014) Francesco Boin et al.   Orphanet Journal of Rare Diseases

Vascular remodelling in the pathogenesis of idiopathic pulmonary fibrosis

(2014) S. Barratt et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

NADPH oxidase-dependent redox signaling in TGF-β-mediated fibrotic responses

(2014) Fan Jiang et al.   Redox Biology

An Inhibitor of NADPH Oxidase-4 Attenuates Established Pulmonary Fibrosis in a Rodent Disease Model

(2013) Elizabeth R Jarman et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Oxidant signaling for interleukin-13 gene expression in lung smooth muscle cells

(2012) Geetanjali Bansal et al.   FREE RADICAL BIOLOGY AND MEDICINE

An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

(2011) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Reply to: "NOX-4 is expressed in thickened pulmonary arteries in idiopathic pulmonary fibrosis"

(2011) Louise Hecker et al.   NATURE MEDICINE

NOX-4 is expressed in thickened pulmonary arteries in idiopathic pulmonary fibrosis

(2011) Jean-Claude Pache et al.   NATURE MEDICINE

Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis

(2010) Corrine R. Kliment et al.   FREE RADICAL BIOLOGY AND MEDICINE

NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGF 1-induced fibroblast differentiation into myofibroblasts

(2010) N. Amara et al.   THORAX

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Akt Downregulation by Flavin Oxidase–Induced ROS Generation Mediates Dose-Dependent Endothelial Cell Damage Elicited by Natural Antioxidants

(2009) Valeria Pasciu et al.   TOXICOLOGICAL SCIENCES