Activation of Na+/K+-ATPase attenuates high glucose-induced H9c2 cell apoptosis via suppressing ROS accumulation and MAPKs activities by DRm217

Mitochondrial complex I defect and increased fatty acid oxidation enhance protein lysine acetylation in the diabetic heart

(2015) Edwin J. Vazquez et al.   CARDIOVASCULAR RESEARCH

Protective effect of pioglitazone on cardiomyocyte apoptosis in low-dose streptozotocin & high-fat diet-induced type-2 diabetes in rats

(2015) Uma Bhandari et al.   INDIAN JOURNAL OF MEDICAL RESEARCH

Diallyl trisulfide protects against high glucose-induced cardiac apoptosis by stimulating the production of cystathionine gamma-lyase-derived hydrogen sulfide

(2015) Cheng-Yen Tsai et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Resveratrol attenuates high glucose-induced oxidative stress and cardiomyocyte apoptosis through AMPK

(2015) Shuang Guo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Glutamine Reduces the Apoptosis of H9C2 Cells Treated with High-Glucose and Reperfusion through an Oxidation-Related Mechanism

(2015) Kai Li et al.   PLoS One

bFGF-Regulating MAPKs Are Involved in High Glucose-Mediated ROS Production and Delay of Vascular Endothelial Cell Migration

(2015) Zhong Xin Zhu et al.   PLoS One

Reduction of Na/K-ATPase affects cardiac remodeling and increases c-kit cell abundance in partial nephrectomized mice

(2014) Christopher A. Drummond et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hydrogen sulfide protected gastric epithelial cell from ischemia/reperfusion injury by Keap1 s-sulfhydration, MAPK dependent anti-apoptosis and NF-κB dependent anti-inflammation pathway

(2014) Cheng Guo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Three pentacyclic triterpenes protect H9c2 cardiomyoblast cells against high-glucose-induced injury

(2014) C. Y. Chan et al.   FREE RADICAL RESEARCH

Inhibiting Na+/K+ ATPase Can Impair Mitochondrial Energetics and Induce Abnormal Ca2+ Cycling and Automaticity in Guinea Pig Cardiomyocytes

(2014) Qince Li et al.   PLoS One

Advanced glycation end-products impair Na+/K+-ATPase activity in diabetic cardiomyopathy: Role of the adenosine monophosphate-activated protein kinase/sirtuin 1 pathway

(2013) Qiong Yuan et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Mechanisms of subcellular remodeling in heart failure due to diabetes

(2013) Naranjan S. Dhalla et al.   HEART FAILURE REVIEWS

High glucose-induced Ca2+ overload and oxidative stress contribute to apoptosis of cardiac cells through mitochondrial dependent and independent pathways

(2012) Sandeep Kumar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Acute Hyperglycemia in Patients With Acute Myocardial Infarction

(2012) Masaharu Ishihara   CIRCULATION JOURNAL

Zinc supplementation prevents cardiomyocyte apoptosis and congenital heart defects in embryos of diabetic mice

(2012) Srinivasan Dinesh Kumar et al.   FREE RADICAL BIOLOGY AND MEDICINE

High glucose levels induce inhibition of Na,K-ATPase via stimulation of aldose reductase, formation of microtubules and formation of an acetylated tubulin/Na,K-ATPase complex

(2012) Juan F. Rivelli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

S-Glutathionylation of the Na,K-ATPase Catalytic α Subunit Is a Determinant of the Enzyme Redox Sensitivity

(2012) Irina Yu. Petrushanko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Concurrent impairment of (Na++K+)-ATPase activity in multi-organ of type-1 diabetic NOD mice

(2012) Qixin Shi et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Oxidative stress and myocardial injury in the diabetic heart

(2012) David M Ansley et al.   JOURNAL OF PATHOLOGY

Mechanistic distinction between activation and inhibition of (Na++K+)-ATPase-mediated Ca2+ influx in cardiomyocytes

(2011) Kai Y. Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protective effects of enalapril in streptozotocin-induced diabetic rat: studies of DNA damage, apoptosis and expression of CCN2 in the heart, kidney and liver

(2011) S. Kushwaha et al.   JOURNAL OF APPLIED TOXICOLOGY

Cardioprotection induced by Na+/K+-ATPase activation involves extracellular signal-regulated kinase 1/2 and phosphoinositide 3-kinase/Akt pathway

(2010) J. Zheng et al.   CARDIOVASCULAR RESEARCH

Bauhinia bauhinioides cruzipain inhibitor reduces endothelial proliferation and induces an increase of the intracellular Ca2+ concentration

(2010) Mehmet Bilgin et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Insulin induced translocation of Na+/K+-ATPase is decreased in the heart of streptozotocin diabetic rats

(2009) Klara Rosta et al.   ACTA PHARMACOLOGICA SINICA

15-HETE suppresses K+ channel activity and inhibits apoptosis in pulmonary artery smooth muscle cells

(2008) Yumei Li et al.   APOPTOSIS