4.6 Article

Reference-free polarization-sensitive quantitative phase imaging using single-point optical phase conjugation

Journal

OPTICS EXPRESS
Volume 26, Issue 21, Pages 26858-26865

Publisher

OPTICAL SOC AMER
DOI: 10.1364/OE.26.026858

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Funding

  1. KAIST
  2. BK21+ program
  3. Tomocube
  4. National Institutes of Health (NIH) [1R01EY017656-06, 1U01NS090438-01, 9P41EB015871-28, 1-R01HL121386-01]
  5. National Research Foundation of Korea [2017M3C1A3013923, 2015R1A3A2066550, 2018K000396]
  6. NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [P41EB015871] Funding Source: NIH RePORTER

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We propose and experimentally demonstrate a method of polarization-sensitive quantitative phase imaging using two photodetectors and a digital micromirror device. Instead of recording wide-field interference patterns, finding the modulation patterns maximizing focused intensities in terms of the polarization states enables polarization-dependent quantitative phase imaging without the need for a reference beam and an image sensor. The feasibility of the present method is experimentally validated by reconstructing Jones matrices of several samples including a polystyrene microsphere, a maize starch granule, and a mouse retinal nerve fiber layer. Since the present method is simple and sufficiently general, we expect that it may offer solutions for quantitative phase imaging of birefringent materials. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

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