Zerumbone Suppresses Human Colorectal Cancer Invasion and Metastasis via Modulation of FAk/PI3k/NFκB-uPA Pathway

Curcumin suppresses colon cancer cell invasion via AMPK-induced inhibition of NF–κB, uPA activator and MMP9

(2016) Weihua Tong et al.   Oncology Letters

Zerumbone Suppresses Osteopontin-Induced Cell Invasion Through Inhibiting the FAK/AKT/ROCK Pathway in Human Non-Small Cell Lung Cancer A549 Cells

(2015) Chi Gu Kang et al.   JOURNAL OF NATURAL PRODUCTS

FAK signaling in human cancer as a target for therapeutics

(2015) Brian Y. Lee et al.   PHARMACOLOGY & THERAPEUTICS

Zerumbone Inhibits Angiogenesis by Blocking NF-κB Activity in Pancreatic Cancer

(2014) Tomoya Shamoto et al.   PANCREAS

Andrographolide, a Novel NF-κB Inhibitor, Induces Vascular Smooth Muscle Cell Apoptosis via a Ceramide-p47phox-ROS Signaling Cascade

(2013) Yu-Ying Chen et al.   Evidence-based Complementary and Alternative Medicine

Zerumbone-loaded nanostructured lipid carriers: preparation, characterization, and antileukemic effect

(2013) Heshu Rahman et al.   International Journal of Nanomedicine

Zerumbone inhibits tumor angiogenesis via NF-κB in gastric cancer

(2013) KEN TSUBOI et al.   ONCOLOGY REPORTS

Zerumbone, a phytochemical from Asian ginger is a novel inhibitor of Jak2/Stat3 inhibits promigratory gene expression, growth and migration of pancreatic cancer cells

(2013) A. Chakraborty et al.   PANCREATOLOGY

Key cell signaling pathways modulated by zerumbone: Role in the prevention and treatment of cancer

(2012) Remya Prasannan et al.   BIOCHEMICAL PHARMACOLOGY

Role of Nuclear Factor-ĸB in Breast and Colorectal Cancer

(2012) Adeel Zubair et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Zerumbone Attenuates the Severity of Acute Necrotizing Pancreatitis and Pancreatitis-Induced Hepatic Injury

(2012) Deng Wenhong et al.   MEDIATORS OF INFLAMMATION

Downregulation of uPAR inhibits migration, invasion, proliferation, FAK/PI3K/Akt signaling and induces senescence in papillary thyroid carcinoma cells

(2011) Theodore S. Nowicki et al.   CELL CYCLE

Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals

(2010) Subash C. Gupta et al.   CANCER AND METASTASIS REVIEWS

Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice

(2010) M.R. Sulaiman et al.   FITOTERAPIA

Zerumbone, a Sesquiterpene from Southeast Asian Edible Ginger Sensitizes Colorectal Cancer Cells to Radiation Therapy

(2010) A. Deorukhkar et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Signal transduction by focal adhesion kinase in cancer

(2009) Jihe Zhao et al.   CANCER AND METASTASIS REVIEWS

Zerumbone Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors in Human Colon Cancer Cells: Evidence for an Essential Role of Reactive Oxygen Species

(2009) S. Yodkeeree et al.   CANCER RESEARCH

Cellular Response to Chemoradiotherapy, Radiotherapy and Chemotherapy in Two Colorectal Cancer Cell Lines

(2009) Birgitte Lid Adamsen et al.   RADIATION RESEARCH

Zerumbone Down-regulates Chemokine Receptor CXCR4 Expression Leading to Inhibition of CXCL12-Induced Invasion of Breast and Pancreatic Tumor Cells

(2008) Bokyung Sung et al.   CANCER RESEARCH

Osteopontin increases lung cancer cells migration via activation of the αvβ3 integrin/FAK/Akt and NF-κB-dependent pathway

(2008) Yi-Chin Fong et al.   LUNG CANCER