Article
Clinical Neurology
Dachao Wei, Dingwei Deng, Siming Gui, Wei You, Junqiang Feng, Xiangyu Meng, Xiheng Chen, Jian Lv, Yudi Tang, Ting Chen, Peng Liu
Summary: This study used machine learning methodology to establish a model for predicting in-stent stenosis (ISS) after Pipeline embolization device (PED) placement. Six predictors of ISS were identified, and the elastic net (ENT) model showed the best predictive performance. This model has the potential to improve patient outcomes in the treatment of intracranial aneurysms.
FRONTIERS IN NEUROLOGY
(2022)
Article
Neuroimaging
Huibin Kang, Bin Luo, Jianmin Liu, Hongqi Zhang, Tianxiao Li, Donglei Song, Yuanli Zhao, Sheng Guan, Aisha Maimaitili, Yunyan Wang, Wenfeng Feng, Yang Wang, Jieqing Wan, Guohua Mao, Huaizhang Shi, Kun Wang, Xinjian Yang
Summary: The Pipeline Embolization Device (PED) has been reported as a safe treatment tool for aneurysms, with a low mortality rate. However, this study found that mortality in patients treated with PED was mainly caused by delayed aneurysm rupture, distal intraparenchymal hemorrhage, and neurological compression. Large basilar aneurysms were associated with a higher risk of postoperative death, requiring increased attention and caution.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Neuroimaging
Siming Gui, Xiheng Chen, Dachao Wei, Dingwei Deng, Wei You, Xiangyu Meng, Jian Lv, Junqiang Feng, Yudi Tang, Shu Yang, Ting Chen, Peng Liu, Huijian Ge, Hengwei Jin, Xinke Liu, Yuhua Jiang, Wei Feng, Youxiang LI
Summary: Flow diverters have greatly improved the treatment of intracranial aneurysms, but the delayed complications associated with their use are not well understood. This study evaluated the occurrence, severity, clinical outcomes, risk factors, and dynamic changes of in-stent stenosis (ISS) after treatment with a Pipeline embolization device (PED). The results show that ISS is a common, benign, and self-limiting complication of PED implantation in the Chinese population.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Neuroimaging
David C. Lauzier, Samuel J. Cler, Arindam R. Chatterjee, Joshua W. Osbun, Christopher J. Moran, Akash P. Kansagra
Summary: Long-term angiography in patients with complete aneurysm occlusion and no in-stent stenosis at 6 months post-treatment may have low value in assessing the treatment outcomes of intracranial aneurysms treated with PED.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Clinical Neurology
Soichiro Fujimura, Alex Brehm, Hiroyuki Takao, Yuya Uchiyama, Kostadin Karagiozov, Koji Fukudome, Makoto Yamamoto, Yuichi Murayama, Marios-Nikos Psychogios
Summary: Using computational fluid dynamics analysis, we found that the energy loss involved with the blood flow passing through an aneurysm and the concentrated inflow into the aneurysm were the most important factors in determining whether an aneurysm would become completely occluded or leave a remnant.
WORLD NEUROSURGERY
(2022)
Article
Neuroimaging
Timothy R. Miller, Mihir Khunte, Nicholas Caffes, Megan Anders, Peter Rock, Amber L. Beitelshees, Ajay Malhotra, Gregory Cannarsa, Jacob Cherian, J. Marc Simard, Gaurav Jindal, Dheeraj Gandhi
Summary: This study aims to explore the phenomenon of increased platelet inhibition following treatment with the Pipeline device and its possible predisposing factors.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Clinical Neurology
Samuel J. Cler, David C. Lauzier, Arindam R. Chatterjee, Joshua W. Osbun, Christopher J. Moran, Akash P. Kansagra
Summary: This study characterized the timeline of aneurysm occlusion following treatment with the Pipeline embolization device (PED) using real-world variability in timing of angiographic follow-up. Larger aneurysms demonstrated a longer median time to occlusion and lower rate of aneurysm occlusion, while the number of PEDs deployed or the use of adjunctive coiling did not affect the time line or likelihood of aneurysm occlusion.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Samuel J. Cler, David C. Lauzier, Arindam R. Chatterjee, Joshua W. Osbun, Christopher J. Moran, Akash P. Kansagra
Summary: This study utilized real-world variability in timing of angiographic follow-up to characterize the time line of aneurysm occlusion following treatment with the Pipeline embolization device (PED). The findings showed that larger aneurysms had a longer median time to occlusion and lower rate of occlusion, but the number of PEDs deployed or the use of adjunctive coiling did not affect the time line or likelihood of aneurysm occlusion. The median time to observed occlusion of aneurysms treated with a PED was 7.5 months.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Jose M. Pumar, Antonio Mosqueira, Jorge Olier, Claudio Rodriguez-Fernandez, Pedro Vega, Eva Gonzalez-Diaz
Summary: The study demonstrates the safety and effectiveness of Silk Vista systems for treating cerebral aneurysms. All patients underwent successful endovascular treatment with short-term follow-up showing most aneurysms with complete or near complete occlusions, and no significant parent artery stenosis observed.
FRONTIERS IN NEUROLOGY
(2021)
Article
Neuroimaging
Mirzat Turhon, Huibin Kang, Mengxing Li, Jian Liu, Yisen Zhang, Ying Zhang, Jiliang Huang, Bin Luo, Jianmin Liu, Hongqi Zhang, Tianxiao Li, Donglei Song, Yuanli Zhao, Sheng Guan, Axir Aximujiang, Aisha Maimaitili, Yunyan Wang, Wenfeng Feng, Yang Wang, Jieqing Wan, Guohua Mao, Huaizhang Shi, Xiaolong Zhang, Yuxiang Gu, Xinjian Yang
Summary: The study evaluated the safety and efficacy of the pipeline embolization device (PED) for treating intracranial fusiform aneurysms. The results showed that PED may be an effective treatment with a favorable occlusion rate. However, caution should be exercised due to the relatively high complication rate.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Neuroimaging
Eytan Raz, Adam Goldman-Yassen, Anna Derman, Ahrya Derakhshani, John Grinstead, Seena Dehkharghani
Summary: This study evaluated the use of high-resolution vessel wall MRI (VWI) for surveillance of flow diverter (FD) treated aneurysms. The results showed that VWI can provide excellent depiction of FD-treated aneurysms and allow robust evaluation of the parent vessel and aneurysm wall.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Neuroimaging
Timothy R. Miller, Aaron Wessell, Gaurav Jindal, Ajay Malhotra, J. Marc Simard, Dheeraj Gandhi
Summary: The study found that P2Y12 hyporesponse was not associated with acute platelet aggregation or ischemic complications in patients undergoing Pipeline embolization of intracranial aneurysms. A greater Pipeline embolization device diameter was linked to a reduced odds of platelet aggregation, while antiplatelet non-compliance and treatment of posterior circulation aneurysms were the only independent predictors of ischemic complications.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Neuroimaging
Chao Wang, Linggen Dong, Jian Liu, Yisen Zhang, Kun Wang, Peng Liu, Xinjian Yang, Ming Lv, Ying Zhang
Summary: In this study, the Atlas SAC and PED were compared for the treatment of proximal internal carotid artery aneurysms. The results showed that the two devices had similar midterm outcomes, but the Atlas SAC had a longer operation time and the PED resulted in higher hospital costs.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Clinical Neurology
Ivan Lylyk, Esteban Scrivano, Javier Lundquist, Angel Ferrario, Carlos Bleise, Nicolas Perez, Pedro Nicolas Lylyk, Rene Viso, Rodolfo Nella-Castro, Pedro Lylyk
Summary: The study from the PEDESTRIAN Registry demonstrated high rates of long-term complete aneurysm occlusion with Pipeline Embolization Devices, stable or improved functional outcomes in patients, and low major morbidity and neurological mortality rates. Clinical and angiographic outcomes improved over long-term follow-up, indicating that endovascular treatment of intracranial aneurysms with PED is safe and effective.
Article
Clinical Neurology
Linggen Dong, Chao Wang, Xiheng Chen, Mingtao Li, Tong Li, He Liu, Yang Zhao, Ran Duan, Weitao Jin, Yukun Zhang, Yang Wang, Ming Lv
Summary: This study developed a nomogram to predict persistent aneurysm filling after pipeline embolization device (PED) treatment, providing a practical approach for neurointerventionalists to evaluate treatment effectiveness and change their strategies.
TRANSLATIONAL STROKE RESEARCH
(2023)
Article
Neuroimaging
Jian Liu, Linkai Jing, Chao Wang, Nikhil Paliwal, Shengzhang Wang, Ying Zhang, Jianping Xiang, Adnan H. Siddiqui, Hui Meng, Xinjian Yang
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2016)
Article
Clinical Neurology
Chao Wang, Zhongbin Tian, Jian Liu, Linkai Jing, Nikhil Paliwal, Shengzhang Wang, Ying Zhang, Jianping Xiang, Adnan H. Siddiqui, Hui Meng, Xinjian Yang
ACTA NEUROCHIRURGICA
(2016)
Article
Medicine, Research & Experimental
Chao Wang, Zhongbin Tian, Jian Liu, Linkai Jing, Nikhil Paliwal, Shengzhang Wang, Ying Zhang, Jianping Xiang, Adnan H. Siddiqui, Hui Meng, Xinjian Yang
JOURNAL OF TRANSLATIONAL MEDICINE
(2016)
Article
Clinical Neurology
Linkai Jing, Jian Liu, Ying Zhang, Nikhil Paliwal, Hui Meng, Shengzhang Wang, Xinjian Yang
WORLD NEUROSURGERY
(2016)
Article
Clinical Neurology
Linkai Jing, Jingru Zhong, Jian Liu, Xinjian Yang, Nikhil Paliwal, Hui Meng, Shengzhang Wang, Ying Zhang
WORLD NEUROSURGERY
(2016)
Article
Biophysics
Nikhil Paliwal, Robert J. Damiano, Nicole A. Varble, Vincent M. Tutino, Zhongwang Dou, Adnan H. Siddiqui, Hui Meng
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
(2017)
Article
Neuroimaging
Qianqian Zhang, Linkai Jing, Jian Liu, Kun Wang, Ying Zhang, Nikhil Paliwal, Hui Meng, Yang Wang, Shengzhang Wang, Xinjian Yang
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2018)
Article
Clinical Neurology
Jian Liu, Linkai Jing, Ying Zhang, Ying Song, Yang Wang, Chuanhui Li, Yanmin Wang, Shiqing Mu, Nikhil Paliwal, Hui Meng, Italo Linfante, Xinjian Yang
WORLD NEUROSURGERY
(2017)
Article
Engineering, Biomedical
Lorenzo Botti, Nikhil Paliwal, Pierangelo Conti, Luca Antiga, Hui Meng
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING
(2018)
Article
Cardiac & Cardiovascular Systems
Philipp Berg, Samuel Voss, Sylvia Saalfeld, Gabor Janiga, Aslak W. Bergersen, Kristian Valen-Sendstad, Jan Bruening, Leonid Goubergrits, Andreas Spuler, Nicole M. Cancelliere, David A. Steinman, Vitor M. Pereira, Tin Lok Chiu, Anderson Chun On Tsang, Bong Jae Chung, Juan R. Cebral, Salvatore Cito, Jordi Pallares, Gabriele Copelli, Benjamin Csippa, Gyorgy Paal, Soichiro Fujimura, Hiroyuki Takao, Simona Hodis, Georg Hille, Christof Karmonik, Saba Elias, Kerstin Kellermann, Muhammad Owais Khan, Alison L. Marsden, Hernan G. Morales, Senol Piskin, Ender A. Finol, Mariya Pravdivtseva, Hamidreza Rajabzadeh-Oghaz, Nikhil Paliwal, Hui Meng, Santhosh Seshadhri, Matthew Howard, Masaaki Shojima, Shin-ichiro Sugiyama, Kuniyasu Niizuma, Sergey Sindeev, Sergey Frolov, Thomas Wagner, Alexander Brawanski, Yi Qian, Yu-An Wu, Kent D. Carlson, Dan Dragomir-Daescu, Oliver Beuing
CARDIOVASCULAR ENGINEERING AND TECHNOLOGY
(2018)
Article
Clinical Neurology
N. Paliwal, V. M. Tutino, H. Shallwani, J. S. Beecher, R. J. Damiano, H. J. Shakir, G. S. Atwal, V. S. Fennell, S. K. Natarajan, E. I. Levy, A. H. Siddiqui, J. M. Davies, H. Meng
AMERICAN JOURNAL OF NEURORADIOLOGY
(2019)
Proceedings Paper
Optics
Nikhil Paliwal, Robert J. Damiano, Jason M. Davies, Adnan H. Siddiqui, Hui Meng
MEDICAL IMAGING 2017: IMAGE-GUIDED PROCEDURES, ROBOTIC INTERVENTIONS, AND MODELING
(2017)
Article
Clinical Neurology
R. J. Damiano, V. M. Tutino, N. Paliwal, D. Ma, J. M. Davies, A. H. Siddiqui, H. Meng
AMERICAN JOURNAL OF NEURORADIOLOGY
(2017)
Proceedings Paper
Optics
Liang Zhao, Danyang Chen, Zihe Chen, Xiangyu Wang, Nikhil Paliwal, Jianping Xiang, Hui Meng, Jason J. Corso, Jinhui Xu
MEDICAL IMAGING 2016: IMAGE-GUIDED PROCEDURES, ROBOTIC INTERVENTIONS, AND MODELING
(2016)