Trans-resveratrol Inhibits Tau Phosphorylation in the Brains of Control and Cadmium Chloride-Treated Rats by Activating PP2A and PI3K/Akt Induced-Inhibition of GSK3β

Neuroprotective Role of Trans-Resveratrol in a Murine Model of Familial Alzheimer's Disease

(2018) David Porquet et al.   JOURNAL OF ALZHEIMERS DISEASE

Effects of cadmium on Bcl-2/Bax expression ratio in rat cortex brain and hippocampus

(2017) S Mahdavi et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Deletion of Type-2 Cannabinoid Receptor Induces Alzheimer’s Disease-Like Tau Pathology and Memory Impairment Through AMPK/GSK3β Pathway

(2017) Lin Wang et al.   MOLECULAR NEUROBIOLOGY

Curcumin administration suppress acetylcholinesterase gene expression in cadmium treated rats

(2017) Ayodele Jacob Akinyemi et al.   NEUROTOXICOLOGY

Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signalling

(2017) Ghada A. Abdel-Aleem et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex

(2017) Susann Schweiger et al.   Scientific Reports

Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK

(2016) Yan-jing Yang et al.   Journal of Neuroinflammation

Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer

(2016) Evan C. Lien et al.   NATURE CELL BIOLOGY

l -Theanine attenuates cadmium-induced neurotoxicity through the inhibition of oxidative damage and tau hyperphosphorylation

(2016) Peiling Ben et al.   NEUROTOXICOLOGY

Role of Environmental Contaminants in the Etiology of Alzheimer’s Disease: A Review

(2015) Manivannan Yegambaram et al.   Current Alzheimer Research

Resveratrol prevents cadmium activation of Erk1/2 and JNK pathways from neuronal cell death via protein phosphatases 2A and 5

(2015) Chunxiao Liu et al.   JOURNAL OF NEUROCHEMISTRY

Astaxanthin reduces type 2 diabetic-associated cognitive decline in rats via activation of PI3K/Akt and attenuation of oxidative stress

(2015) XIAOBIN LI et al.   Molecular Medicine Reports

Alzheimer disease therapeutics: Focus on the disease and not just plaques and tangles

(2014) Khalid Iqbal et al.   BIOCHEMICAL PHARMACOLOGY

Abeta, oxidative stress in Alzheimer disease: Evidence based on proteomics studies

(2013) Aaron M. Swomley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin

(2013) Hans Zempel et al.   EMBO JOURNAL

Chicoric Acid Induces Apoptosis in 3T3-L1 Preadipocytes through ROS-Mediated PI3K/Akt and MAPK Signaling Pathways

(2013) Haifang Xiao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Mammalian Target of Rapamycin (mTor) Mediates Tau Protein Dyshomeostasis

(2013) Zhi Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroprotective Effects of Resveratrol Against Aβ Administration in Rats are Improved by Lipid-Core Nanocapsules

(2013) Rudimar L. Frozza et al.   MOLECULAR NEUROBIOLOGY

Cadmium and Its Neurotoxic Effects

(2013) Bo Wang et al.   Oxidative Medicine and Cellular Longevity

Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory

(2012) Yiying Zhang et al.   ANNALS OF NEUROLOGY

Isoorientin induces apoptosis through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway in HepG2 cancer cells

(2012) Li Yuan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

An IκBα phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)–Nrf2–ARE signaling and ROS–PI3K/Akt signaling in an NF-κB-independent mechanism

(2011) Kyoung-jin Min et al.   CELLULAR SIGNALLING

CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death

(2011) Sujuan Chen et al.   JOURNAL OF NEUROCHEMISTRY

Resveratrol induces Sirt1-dependent apoptosis in 3T3-L1 preadipocytes by activating AMPK and suppressing AKT activity and survivin expression

(2011) Sifan Chen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Molecular Implication of PP2A and Pin1 in the Alzheimer's Disease Specific Hyperphosphorylation of Tau

(2011) Isabelle Landrieu et al.   PLoS One

Alzheimer's Disease

(2011) D. J. Selkoe   Cold Spring Harbor Perspectives in Biology

Protective effect of quercetin against intracerebral streptozotocin induced reduction in cerebral blood flow and impairment of memory in mice

(2010) Santoshkumar Tota et al.   BEHAVIOURAL BRAIN RESEARCH

N-acetylcysteine prevents memory deficits, the decrease in acetylcholinesterase activity and oxidative stress in rats exposed to cadmium

(2010) Jamile F. Gonçalves et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

(2010) Long Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effect of glutathione on the cadmium chelation of EDTA in a patient with cadmium intoxication

(2010) Hyo-wook Gil et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Molecular mechanisms of neurodegeneration in Alzheimer's disease

(2010) L. Crews et al.   HUMAN MOLECULAR GENETICS

RETRACTED: Implication of phosphatidylinositol-3 kinase/Akt/glycogen synthase kinase-3β pathway in ginsenoside Rb1's attenuation of beta-amyloid-induced neurotoxicity and tau phosphorylation

(2010) Ruiping Zhao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Upregulation of RGS4 expression by IL-1β in colonic smooth muscle is enhanced by ERK1/2 and p38 MAPK and inhibited by the PI3K/Akt/GSK3β pathway

(2009) Wenhui Hu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cadmium Toxicity toward Autophagy through ROS-Activated GSK-3β in Mesangial Cells

(2009) Sheng-Hao Wang et al.   TOXICOLOGICAL SCIENCES

Mechanism of Tau-Induced Neurodegeneration in Alzheimer Disease and Related Tauopathies

(2008) Alejandra del Alonso et al.   Current Alzheimer Research

Metals in Alzheimer's and Parkinson's Diseases

(2008) Kevin J Barnham et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

(2008) Long Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

mTOR-dependent signalling in Alzheimer's disease

(2008) Jin-Jing Pei et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Neuroprotective effects of donepezil through inhibition of GSK-3 activity in amyloid-β-induced neuronal cell death

(2008) Min-Young Noh et al.   JOURNAL OF NEUROCHEMISTRY

Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease

(2008) Saravanan S. Karuppagounder et al.   NEUROCHEMISTRY INTERNATIONAL