Progress in the understanding of polycystic kidney disease

Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney

(2018) Bo Zhang et al.   DEVELOPMENT

Cilia‐localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney

(2018) Amandine Viau et al.   EMBO JOURNAL

A Mutation Affecting Polycystin-1 Mediated Heterotrimeric G-Protein Signaling Causes PKD

(2018) Stephen C Parnell et al.   HUMAN MOLECULAR GENETICS

Somatic Mutations in Renal Cyst Epithelium in Autosomal Dominant Polycystic Kidney Disease

(2018) Adrian Y. Tan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mcp1 Promotes Macrophage-Dependent Cyst Expansion in Autosomal Dominant Polycystic Kidney Disease

(2018) Marcelo F. Cassini et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Structure of the human PKD1-PKD2 complex

(2018) Qiang Su et al.   SCIENCE

The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs

(2016) Peter S. Shen et al.   CELL

Diagnosis of autosomal dominant polycystic kidney disease using efficientPKD1andPKD2targeted next-generation sequencing

(2014) Daniel Trujillano et al.   Molecular Genetics & Genomic Medicine