Time to abandon single-site irradiation for inducing abscopal effects
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Time to abandon single-site irradiation for inducing abscopal effects
Authors
Keywords
-
Journal
Nature Reviews Clinical Oncology
Volume 16, Issue 2, Pages 123-135
Publisher
Springer Nature
Online
2018-11-06
DOI
10.1038/s41571-018-0119-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Pembrolizumab for the Treatment of Advanced Salivary Gland Carcinoma
- (2018) Roger B. Cohen et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- Pembrolizumab for advanced prostate adenocarcinoma: findings of the KEYNOTE-028 study
- (2018) A R Hansen et al. ANNALS OF ONCOLOGY
- Abscopal Effects With Hypofractionated Schedules Extending Into the Effector Phase of the Tumor-Specific T-Cell Response
- (2018) Xuanwei Zhang et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors
- (2018) Jason J. Luke et al. JOURNAL OF CLINICAL ONCOLOGY
- Safety and Antitumor Activity of the Anti–Programmed Death-1 Antibody Pembrolizumab in Patients With Advanced Esophageal Carcinoma
- (2018) Toshihiko Doi et al. JOURNAL OF CLINICAL ONCOLOGY
- Combination ipilimumab and radiosurgery for brain metastases: tumor, edema, and adverse radiation effects
- (2018) Kevin Diao et al. JOURNAL OF NEUROSURGERY
- Abscopal Effect after Radioembolization for Metastatic Breast Cancer in the Setting of Immunotherapy
- (2018) Amy R. Deipolyi et al. JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
- Safety of combining radiotherapy with immune-checkpoint inhibition
- (2018) William L. Hwang et al. Nature Reviews Clinical Oncology
- CAR T cell immunotherapy for human cancer
- (2018) Carl H. June et al. SCIENCE
- Bayesian basket trial design with exchangeability monitoring
- (2018) Brian P. Hobbs et al. STATISTICS IN MEDICINE
- Immunotherapy and Symptomatic Radiation Necrosis in Patients With Brain Metastases Treated With Stereotactic Radiation
- (2018) Allison M. Martin et al. JAMA Oncology
- Consolidative Radiotherapy for Limited Metastatic Non–Small-Cell Lung Cancer
- (2018) Puneeth Iyengar et al. JAMA Oncology
- A phase II randomized trial of nivolumab with stereotactic body radiotherapy (SBRT) versus nivolumab alone in metastatic (M1) head and neck squamous cell carcinoma (HNSCC).
- (2018) Sean Matthew McBride et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II randomized clinical trial comparing immunotherapy plus stereotactic ablative radiotherapy (I-SABR) versus SABR alone for stage I, selected stage IIa or isolated lung parenchymal recurrent non-small cell lung cancer: I-SABR.
- (2018) Joe Y. Chang et al. JOURNAL OF CLINICAL ONCOLOGY
- Antitumor activity and safety of pembrolizumab in patients with advanced recurrent ovarian cancer: Interim results from the phase 2 KEYNOTE-100 study.
- (2018) Ursula A. Matulonis et al. JOURNAL OF CLINICAL ONCOLOGY
- Abscopal, immunological effects of radiotherapy: Narrowing the gap between clinical and preclinical experiences
- (2017) Nikko Brix et al. IMMUNOLOGICAL REVIEWS
- Phase 1 Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma Patients With Brain Metastases
- (2017) Noelle L. Williams et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Phase 2 5-Arm Trial of Ipilimumab Plus Lung or Liver Stereotactic Radiation for Patients with Advanced Malignancies
- (2017) J.W. Welsh et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Safety and Efficacy of Pembrolizumab in Advanced, Programmed Death Ligand 1–Positive Cervical Cancer: Results From the Phase Ib KEYNOTE-028 Trial
- (2017) Jean-Sebastien Frenel et al. JOURNAL OF CLINICAL ONCOLOGY
- Safety and Antitumor Activity of Pembrolizumab in Advanced Programmed Death Ligand 1–Positive Endometrial Cancer: Results From the KEYNOTE-028 Study
- (2017) Patrick A. Ott et al. JOURNAL OF CLINICAL ONCOLOGY
- Pembrolizumab in Patients With Extensive-Stage Small-Cell Lung Cancer: Results From the Phase Ib KEYNOTE-028 Study
- (2017) Patrick A. Ott et al. JOURNAL OF CLINICAL ONCOLOGY
- Randomized, Double-Blind, Phase III Trial of Ipilimumab Versus Placebo in Asymptomatic or Minimally Symptomatic Patients With Metastatic Chemotherapy-Naive Castration-Resistant Prostate Cancer
- (2017) Tomasz M. Beer et al. JOURNAL OF CLINICAL ONCOLOGY
- PUB013 Randomized Phase II Study of Pembrolizumab after SBRT versus Pembrolizumab Alone in Patients with Advanced NSCLC, Preliminary Results
- (2017) Willemijn Theelen et al. Journal of Thoracic Oncology
- Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study
- (2017) Matthew D Hellmann et al. LANCET ONCOLOGY
- Clinical safety and activity of pembrolizumab in patients with malignant pleural mesothelioma (KEYNOTE-028): preliminary results from a non-randomised, open-label, phase 1b trial
- (2017) Evan W Alley et al. LANCET ONCOLOGY
- Concurrent radiotherapy for patients with metastatic melanoma and receiving anti-programmed-death 1 therapy
- (2017) Amélie Aboudaram et al. MELANOMA RESEARCH
- T-cell invigoration to tumour burden ratio associated with anti-PD-1 response
- (2017) Alexander C. Huang et al. NATURE
- Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer
- (2017) Scott J. Antonia et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tumor Mutational Burden and Response Rate to PD-1 Inhibition
- (2017) Mark Yarchoan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Exceptional Response to Nivolumab and Stereotactic Body Radiation Therapy (SBRT) in Neuroendocrine Cervical Carcinoma with High Tumor Mutational Burden: Management Considerations from the Center For Personalized Cancer Therapy at UC San Diego Moores Cancer Center
- (2017) Andrew Sharabi et al. ONCOLOGIST
- DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity
- (2017) Claire Vanpouille-Box et al. Nature Communications
- Hypofractionated Irradiation Has Immune Stimulatory Potential and Induces a Timely Restricted Infiltration of Immune Cells in Colon Cancer Tumors
- (2017) Benjamin Frey et al. Frontiers in Immunology
- Immunotherapy resistance: the answers lie ahead – not in front – of us
- (2017) Miles C. Andrews et al. Journal for ImmunoTherapy of Cancer
- Clinical and molecular markers of long-term survival after oligometastasis-directed stereotactic body radiotherapy (SBRT)
- (2016) Anthony C. Wong et al. CANCER
- Abscopal regression following SABR for non-small-cell-lung cancer: A case report
- (2016) Yang Cong et al. CANCER BIOLOGY & THERAPY
- Ipilimumab with Stereotactic Ablative Radiation Therapy: Phase I Results and Immunologic Correlates from Peripheral T Cells
- (2016) Chad Tang et al. CLINICAL CANCER RESEARCH
- Systematic review of case reports on the abscopal effect
- (2016) Yazan Abuodeh et al. CURRENT PROBLEMS IN CANCER
- The immune mechanisms of abscopal effect in radiation therapy
- (2016) G. Daniel Grass et al. CURRENT PROBLEMS IN CANCER
- Abscopal effect in a Hodgkin lymphoma patient treated by an anti-programmed death 1 antibody
- (2016) Jean-Marie Michot et al. EUROPEAN JOURNAL OF CANCER
- Abscopal Effect in Congenital Fibrosarcoma With Novel EML4-NTRK3 Fusion
- (2016) S.M. Barton et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Abscopal Effect in Patients With Metastatic Melanoma Treated With Checkpoint Inhibitors (Anti-CTLA-4 and Anti-PD1): A Retrospective Analysis of a Single Institution
- (2016) R.F. Carvalho et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- The Abscopal Effect in Patients With Multiple Metastases Treated With Combination of Dendritic Cell-Based Immunotherapy and Focal Radiation Therapy
- (2016) K. Nakajima et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Safety and Efficacy of Radiation Therapy in Advanced Melanoma Patients Treated With Ipilimumab
- (2016) Rosie Qin et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Analysis of the Abscopal Effect With Anti-PD1 Therapy in Patients With Metastatic Solid Tumors
- (2016) Jéssica Ribeiro Gomes et al. JOURNAL OF IMMUNOTHERAPY
- Does immunotherapy increase the rate of radiation necrosis after radiosurgical treatment of brain metastases?
- (2016) Rovel J. Colaco et al. JOURNAL OF NEUROSURGERY
- Local consolidative therapy versus maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer without progression after first-line systemic therapy: a multicentre, randomised, controlled, phase 2 study
- (2016) Daniel R Gomez et al. LANCET ONCOLOGY
- Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial
- (2016) Tanguy Y Seiwert et al. LANCET ONCOLOGY
- Immunotherapy and stereotactic ablative radiotherapy (ISABR): a curative approach?
- (2016) Michael B. Bernstein et al. Nature Reviews Clinical Oncology
- Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
- (2016) Jesse M. Zaretsky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Abscopal effect in metastatic renal cell carcinoma
- (2016) Mieke Van de Walle et al. ACTA CLINICA BELGICA
- Role of Radiation Therapy as Immune Activator in the Era of Modern Immunotherapy for Metastatic Malignant Melanoma
- (2015) Derick Okwan-Duodu et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- The effect of ionizing radiation on regulatory T cells in health and disease
- (2015) Eszter Persa et al. CANCER LETTERS
- Ablative Tumor Radiation Can Change the Tumor Immune Cell Microenvironment to Induce Durable Complete Remissions
- (2015) A. Filatenkov et al. CLINICAL CANCER RESEARCH
- 525 Safety and efficacy of pembrolizumab (MK-3475) in patients (pts) with advanced biliary tract cancer: Interim results of KEYNOTE-028
- (2015) Y.J. Bang et al. EUROPEAN JOURNAL OF CANCER
- Abscopal-Effekt in der Therapie des malignen Melanoms
- (2015) C. Thallinger et al. HAUTARZT
- Immune Checkpoint Blockade in Cancer Therapy
- (2015) Michael A. Postow et al. JOURNAL OF CLINICAL ONCOLOGY
- Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial
- (2015) Encouse B Golden et al. LANCET ONCOLOGY
- Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
- (2015) Christina Twyman-Saint Victor et al. NATURE
- Nivolumab and Ipilimumab versus Ipilimumab in Untreated Melanoma
- (2015) Michael A. Postow et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer
- (2015) Julie Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer
- (2015) Hossein Borghaei et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma
- (2015) Robert J. Motzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
- Myeloid-Derived Cells in Tumors: Effects of Radiation
- (2015) Ralph E. Vatner et al. SEMINARS IN RADIATION ONCOLOGY
- Current Clinical Trials Testing Combinations of Immunotherapy and Radiation
- (2015) Marka Crittenden et al. SEMINARS IN RADIATION ONCOLOGY
- Abskopale Effekte der lokalen Radiotherapie in Kombination mit systemischer Immuntherapie bei Patienten mit metastasierten soliden Tumoren
- (2015) Cédric Panje et al. STRAHLENTHERAPIE UND ONKOLOGIE
- A systematic evaluation of abscopal responses following radiotherapy in patients with metastatic melanoma treated with ipilimumab
- (2015) Ravi A Chandra et al. OncoImmunology
- Role of Local Radiation Therapy in Cancer Immunotherapy
- (2015) Sandra Demaria et al. JAMA Oncology
- Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing
- (2015) Sofia R. Gameiro et al. Oncotarget
- STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
- (2014) Liufu Deng et al. IMMUNITY
- Kill and spread the word: stimulation of antitumor immune responses in the context of radiotherapy
- (2014) Udo S Gaipl et al. Immunotherapy
- Propensity Score–Matched Analysis of Comprehensive Local Therapy for Oligometastatic Non-Small Cell Lung Cancer That Did Not Progress After Front-Line Chemotherapy
- (2014) Tommy Sheu et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Stereotactic Ablative Radiation Therapy for Centrally Located Early Stage or Isolated Parenchymal Recurrences of Non-Small Cell Lung Cancer: How to Fly in a “No Fly Zone”
- (2014) Joe Y. Chang et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Radiation-Induced CXCL16 Release by Breast Cancer Cells Attracts Effector T Cells
- (2014) S. Matsumura et al. JOURNAL OF IMMUNOLOGY
- Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial
- (2014) Eugene D Kwon et al. LANCET ONCOLOGY
- The potential of positron emission tomography for intratreatment dynamic lung tumor tracking: A phantom study
- (2014) Jaewon Yang et al. MEDICAL PHYSICS
- Cancer Epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance
- (2014) Hariharan Easwaran et al. MOLECULAR CELL
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- Radiotherapy and the Tumor Stroma: The Importance of Dose and Fractionation
- (2014) Turid Hellevik et al. Frontiers in Oncology
- Combinations of Immunotherapy and Radiation in Cancer Therapy
- (2014) Ralph E. Vatner et al. Frontiers in Oncology
- CSF1R Signaling Blockade Stanches Tumor-Infiltrating Myeloid Cells and Improves the Efficacy of Radiotherapy in Prostate Cancer
- (2013) J. Xu et al. CANCER RESEARCH
- The Abscopal Effect Associated With a Systemic Anti-melanoma Immune Response
- (2013) Emily F. Stamell et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Radiation and immunotherapy: a synergistic combination
- (2013) Anusha Kalbasi et al. JOURNAL OF CLINICAL INVESTIGATION
- Radiation-Induced Equilibrium Is a Balance between Tumor Cell Proliferation and T Cell-Mediated Killing
- (2013) H. Liang et al. JOURNAL OF IMMUNOLOGY
- Toward a planning scheme for emission guided radiation therapy (EGRT): FDG based tumor tracking in a metastatic breast cancer patient
- (2013) Qiyong Fan et al. MEDICAL PHYSICS
- Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer
- (2013) Sarah C. Darby et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab plus Ipilimumab in Advanced Melanoma
- (2013) Jedd D. Wolchok et al. NEW ENGLAND JOURNAL OF MEDICINE
- Concurrent Radiotherapy and Ipilimumab Immunotherapy for Patients with Melanoma
- (2013) C. A. Barker et al. Cancer Immunology Research
- An Abscopal Response to Radiation and Ipilimumab in a Patient with Metastatic Non-Small Cell Lung Cancer
- (2013) E. B. Golden et al. Cancer Immunology Research
- Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies
- (2012) I. Verbrugge et al. CANCER RESEARCH
- Synergy of Topical Toll-like Receptor 7 Agonist with Radiation and Low-Dose Cyclophosphamide in a Mouse Model of Cutaneous Breast Cancer
- (2012) M. Z. Dewan et al. CLINICAL CANCER RESEARCH
- Spontaneous Regression of Thoracic Metastases While Progression of Brain Metastases After Stereotactic Radiosurgery and Stereotactic Body Radiotherapy for Metastatic Renal Cell Carcinoma: Abscopal Effect Prevented by the Blood-Brain Barrier?
- (2012) Hiromichi Ishiyama et al. Clinical Genitourinary Cancer
- Serial assessment of lymphocytes and apoptosis in the prostate during coordinated intraprostatic dendritic cell injection and radiotherapy
- (2012) Steven Eric Finkelstein et al. Immunotherapy
- Emission guided radiation therapy for lung and prostate cancers: A feasibility study on a digital patient
- (2012) Qiyong Fan et al. MEDICAL PHYSICS
- Abscopal Effect in a Patient with Melanoma
- (2012) NEW ENGLAND JOURNAL OF MEDICINE
- Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma
- (2012) Michael A. Postow et al. NEW ENGLAND JOURNAL OF MEDICINE
- The convergence of radiation and immunogenic cell death signaling pathways
- (2012) Encouse B. Golden et al. Frontiers in Oncology
- Abscopal Effect in a Patient With Metastatic Merkel Cell Carcinoma Following Radiation Therapy: Potential Role of Induced Antitumor Immunity
- (2011) Shane E. Cotter ARCHIVES OF DERMATOLOGY
- Intratumoral injection of interleukin-2 augments the local and abscopal effects of radiotherapy in murine rectal cancer
- (2011) Koji Yasuda et al. CANCER SCIENCE
- Maximizing Tumor Immunity With Fractionated Radiation
- (2011) Dörthe Schaue et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Clinical Outcomes of Stereotactic Brain and/or Body Radiotherapy for Patients with Oligometastatic Lesions
- (2010) T. Inoue et al. JAPANESE JOURNAL OF CLINICAL ONCOLOGY
- Surgical treatment of oligometastatic non-small cell lung cancer
- (2010) Joachim Pfannschmidt et al. LUNG CANCER
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Links between Innate Immunity and Normal Tissue Radiobiology
- (2010) Dörthe Schaue et al. RADIATION RESEARCH
- Tumor heterogeneity: Causes and consequences
- (2009) Andriy Marusyk et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment
- (2009) Y. Lee et al. BLOOD
- Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti-CTLA-4 Antibody
- (2009) M. Z. Dewan et al. CLINICAL CANCER RESEARCH
- Abscopal Effect on Hepatocellular Carcinoma
- (2008) Mitsuru Nakanishi et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Enhancement of Antitumor Radiation Efficacy and Consistent Induction of the Abscopal Effect in Mice by ECI301, an Active Variant of Macrophage Inflammatory Protein-1
- (2008) K. Shiraishi et al. CLINICAL CANCER RESEARCH
- An Initial Report of a Radiation Dose-Escalation Trial in Patients with One to Five Sites of Metastatic Disease
- (2008) J. K. Salama et al. CLINICAL CANCER RESEARCH
- New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
- (2008) E.A. Eisenhauer et al. EUROPEAN JOURNAL OF CANCER
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started