A fully automatic method yielding initial models from high-resolution cryo-electron microscopy maps

De novo main-chain modeling for EM maps using MAINMAST

(2018) Genki Terashi et al.   Nature Communications

Automated map sharpening by maximization of detail and connectivity

(2018) Thomas C. Terwilliger et al.   Acta Crystallographica Section D-Structural Biology

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

Map segmentation, automated model-building and their application to the Cryo-EM Model Challenge

(2018) Thomas C. Terwilliger et al.   JOURNAL OF STRUCTURAL BIOLOGY

Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3

(2017) Stefan Schoebel et al.   NATURE

RosettaES: a sampling strategy enabling automated interpretation of difficult cryo-EM maps

(2017) Brandon Frenz et al.   NATURE METHODS

Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin

(2017) Moran Shalev-Benami et al.   Nature Communications

Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery

(2016) Alan Merk et al.   CELL

De Novo modeling in cryo-EM density maps with Pathwalking

(2016) Muyuan Chen et al.   JOURNAL OF STRUCTURAL BIOLOGY

Overview and future of single particle electron cryomicroscopy

(2015) Richard Henderson   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins

(2015) Rui Zhang et al.   CELL

De novo protein structure determination from near-atomic-resolution cryo-EM maps

(2015) Ray Yu-Ruei Wang et al.   NATURE METHODS

EMDataBank unified data resource for 3DEM

(2015) Catherine L. Lawson et al.   NUCLEIC ACIDS RESEARCH

2.2 A resolution cryo-EM structure of  -galactosidase in complex with a cell-permeant inhibitor

(2015) A. Bartesaghi et al.   SCIENCE

The Resolution Revolution

(2014) W. Kuhlbrandt   SCIENCE

Model morphing and sequence assignment after molecular replacement

(2013) Thomas C. Terwilliger et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Rapid chain tracing of polypeptide backbones in electron-density maps

(2010) Thomas C. Terwilliger   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Rapid model building of α-helices in electron-density maps

(2010) Thomas C. Terwilliger   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions

(2010) Grigore D. Pintilie et al.   JOURNAL OF STRUCTURAL BIOLOGY