Autocrine–paracrine prostaglandin E2 signaling restricts TLR4 internalization and TRIF signaling

The Induction of Pro–IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E2Production

(2017) Zbigniew Zasłona et al.   JOURNAL OF IMMUNOLOGY

Anthrax edema toxin disrupts distinct steps in Rab11-dependent junctional transport

(2017) Annabel Guichard et al.   PLoS Pathogens

Type I interferon signaling restrains IL-10R+ colonic macrophages and dendritic cells and leads to more severe Salmonella colitis

(2017) Kailyn L. Stefan et al.   PLoS One

Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue

(2016) Virginia Castiglia et al.   Cell Host & Microbe

Type I interferon licenses enhanced innate recognition and transcriptional responses to Franciscella tularensis live vaccine strain

(2016) Katharina Richard et al.   Innate Immunity

NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations

(2016) Leanne Mortimer et al.   NATURE IMMUNOLOGY

Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell-IL-22 axis

(2016) R. Duffin et al.   SCIENCE

Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons

(2016) Elisa Deriu et al.   PLoS Pathogens

Innate Immune Pattern Recognition: A Cell Biological Perspective

(2015) Sky W. Brubaker et al.   Annual Review of Immunology

SalmonellaTyphimurium Co-Opts the Host Type I IFN System To Restrict Macrophage Innate Immune Transcriptional Responses Selectively

(2015) Darren J. Perkins et al.   JOURNAL OF IMMUNOLOGY

A RIPK3–Caspase 8 Complex Mediates Atypical Pro–IL-1β Processing

(2015) Kenta Moriwaki et al.   JOURNAL OF IMMUNOLOGY

Toll-like receptor signalling through macromolecular protein complexes

(2015) Clare E. Bryant et al.   MOLECULAR IMMUNOLOGY

CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance

(2015) Rajesh Rajaiah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caspase-1 Cleavage of the TLR Adaptor TRIF Inhibits Autophagy and β-Interferon Production during Pseudomonas aeruginosa Infection

(2014) Majid Sakhi Jabir et al.   Cell Host & Microbe

Prostaglandin E2 Suppresses Lipopolysaccharide-Stimulated IFN-  Production

(2014) X. J. Xu et al.   JOURNAL OF IMMUNOLOGY

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

(2014) Katrin D. Mayer-Barber et al.   NATURE

RAB11-mediated trafficking in host–pathogen interactions

(2014) Annabel Guichard et al.   NATURE REVIEWS MICROBIOLOGY

Cholera Toxin Disrupts Barrier Function by Inhibiting Exocyst-Mediated Trafficking of Host Proteins to Intestinal Cell Junctions

(2013) Annabel Guichard et al.   Cell Host & Microbe

The Small GTPase Arf6 Is Essential for the Tram/Trif Pathway in TLR4 Signaling

(2013) Tim Van Acker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E-type prostanoid receptor 4 (EP4) in disease and therapy

(2013) Viktoria Konya et al.   PHARMACOLOGY & THERAPEUTICS

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

(2012) Jakob von Moltke et al.   NATURE

Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

(2012) Nirmal Robinson et al.   NATURE IMMUNOLOGY

Human TLRs and IL-1Rs in Host Defense: Natural Insights from Evolutionary, Epidemiological, and Clinical Genetics

(2011) Jean-Laurent Casanova et al.   Annual Review of Immunology

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

Innate and Adaptive Interferons Suppress IL-1α and IL-1β Production by Distinct Pulmonary Myeloid Subsets during Mycobacterium tuberculosis Infection

(2011) Katrin D. Mayer-Barber et al.   IMMUNITY

Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway

(2011) S. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes

(2010) Harald Husebye et al.   IMMUNITY

Induction of IFN-αβ enablesListeria monocytogenesto suppress macrophage activation by IFN-γ

(2010) Manira Rayamajhi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I IFN Signaling Constrains IL-17A/F Secretion by    T Cells during Bacterial Infections

(2010) T. Henry et al.   JOURNAL OF IMMUNOLOGY

The anti-tumor agent, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), induces IFN-β-mediated antiviral activity in vitro and in vivo

(2010) Kari Ann Shirey et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Anthrax toxins cooperatively inhibit endocytic recycling by the Rab11/Sec15 exocyst

(2010) Annabel Guichard et al.   NATURE

Type I Interferon Signaling Exacerbates Chlamydia muridarum Genital Infection in a Murine Model

(2008) U. M. Nagarajan et al.   INFECTION AND IMMUNITY

Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20

(2008) Emre E. Turer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stimulation of Toll-like receptor 3 and 4 induces interleukin-1β maturation by caspase-8

(2008) Jonathan Maelfait et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY