Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells

Regeneration of pancreatic insulin-producing cells by in situ adaptive cell conversion

(2016) Simona Chera et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Stress-induced adaptive islet cell identity changes

(2016) V. Cigliola et al.   DIABETES OBESITY & METABOLISM

Pancreatic β cell identity requires continual repression of non–β cell programs

(2016) Giselle Domínguez Gutiérrez et al.   JOURNAL OF CLINICAL INVESTIGATION

PAX6 maintains β cell identity by repressing genes of alternative islet cell types

(2016) Avital Swisa et al.   JOURNAL OF CLINICAL INVESTIGATION

Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist

(2016) Nicolas Damond et al.   eLife

The Role of Cell Plasticity in Tissue Repair: Adaptive Cellular Reprogramming

(2015) Kristjan R. Jessen et al.   DEVELOPMENTAL CELL

Pdx1 Maintains β Cell Identity and Function by Repressing an α Cell Program

(2014) Tao Gao et al.   Cell Metabolism

Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers

(2014) Simona Chera et al.   NATURE

Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells

(2014) Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RETRACTED: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation

(2013) Peng Yi et al.   CELL

Expression of Mesenchymal and  -Cell Phenotypic Markers in Islet  -Cells in Recently Diagnosed Diabetes

(2013) M. G. White et al.   DIABETES CARE

Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell Identity

(2013) Ashleigh E. Schaffer et al.   PLoS Genetics

Regeneration and reprogramming

(2012) Dunja Knapp et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Maintenance of  -Cell Maturity and Plasticity in the Adult Pancreas: Developmental Biology Concepts in Adult Physiology

(2012) M. Szabat et al.   DIABETES

Reduced white fat mass in adult mice bearing a truncated Patched 1

(2012) Zili Li et al.   International Journal of Biological Sciences

Maintaining differentiated cellular identity

(2012) Johan Holmberg et al.   NATURE REVIEWS GENETICS

Normal Glucagon Signaling and β-Cell Function After Near-Total α-Cell Ablation in Adult Mice

(2011) Fabrizio Thorel et al.   DIABETES

Delta-cell-specific expression of hedgehog pathway Ptch1 receptor in murine and human endocrine pancreas

(2011) F. A. Grieco et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Quantification of factors influencing fluorescent protein expression using RMCE to generate an allelic series in the ROSA26 locus in mice

(2011) S. X. Chen et al.   Disease Models & Mechanisms

Context-specific  -to- -cell reprogramming by forced Pdx1 expression

(2011) Y.-P. Yang et al.   GENES & DEVELOPMENT

Nkx2.2 repressor complex regulates islet  -cell specification and prevents  -to- -cell reprogramming

(2011) J. B. Papizan et al.   GENES & DEVELOPMENT

Elevated Hedgehog/Gli signaling causes  -cell dedifferentiation in mice

(2011) L. Landsman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic factors influencing resistance to nuclear reprogramming

(2011) Vincent Pasque et al.   TRENDS IN GENETICS

S961, an insulin receptor antagonist causes hyperinsulinemia, insulin-resistance and depletion of energy stores in rats

(2010) Ajit Vikram et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Epigenetic Mechanisms that Regulate Cell Identity

(2010) María J. Barrero et al.   Cell Stem Cell

Hedgehog Signaling in Pancreas Epithelium Regulates Embryonic Organ Formation and Adult  -Cell Function

(2010) J. Lau et al.   DIABETES

Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy

(2010) A. E. Butler et al.   DIABETOLOGIA

Maintaining Cell Identity through Global Control of Genomic Organization

(2010) Gioacchino Natoli   IMMUNITY

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Primary cilia regulate Gli/Hedgehog activation in pancreas

(2010) S. Cervantes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal Phenotype in the Mature Nervous System Is Maintained by Persistent Retrograde Bone Morphogenetic Protein Signaling

(2009) K. T. Eade et al.   JOURNAL OF NEUROSCIENCE

Mice Deficient for Glucagon Gene-Derived Peptides Display Normoglycemia and Hyperplasia of Islet α-Cells But Not of Intestinal L-Cells

(2009) Yoshitaka Hayashi et al.   MOLECULAR ENDOCRINOLOGY

A novel high-affinity peptide antagonist to the insulin receptor

(2008) Lauge Schäffer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS