Article
Chemistry, Applied
Ying-Ying Song, Meng-Meng Song, Wei-Hao Chen, Xiao-Yan Pang, Fa-Zuo Wang, Xin-Peng Tian, Jun-Feng Wang, Yong-Hong Liu
Summary: A new furanone analog and six known compounds were isolated from a deep-sea fungus. One of the compounds exhibited modest antioxidant activity while others showed pancreatic lipase inhibitory activities.
NATURAL PRODUCT RESEARCH
(2023)
Article
Chemistry, Medicinal
Wei-Mao Zhong, Xiao-Yi Wei, Yu-Chan Chen, Qi Zeng, Jun-Feng Wang, Xue-Feng Shi, Xin-Peng Tian, Wei-Min Zhang, Fa-Zuo Wang, Si Zhang
Summary: Through large-scale fermentation with modified culture, new salicylaldehyde derivative enantiomers were isolated from Eurotium sp. SCSIO F452, showing significant inhibitory activity against alpha-glucosidase and moderate cytotoxic activities against various cell lines.
Article
Biochemistry & Molecular Biology
Imran Khan, Jing Peng, Zhuangjie Fang, Wei Liu, Wenjun Zhang, Qingbo Zhang, Liang Ma, Guangtao Zhang, Changsheng Zhang, Haibo Zhang
Summary: A fungus strain Tolypocladium cylindrosporum was isolated from an Arctic-derived glacier sediment sample, producing a new compound cylindromicin and seven known secondary metabolites. The chemical structures of these compounds were determined through comprehensive spectroscopic analyses. Cylindromicin exhibited significant tyrosinase inhibition activity, showcasing Polar fungi as a potential source for new bioactive natural products.
Article
Chemistry, Organic
Weimao Zhong, Yuchan Chen, Xiaoyi Wei, Junfeng Wang, Qi Zeng, Xinpeng Tian, Weimin Zhang, Fazuo Wang, Si Zhang
Summary: Euroticins C-E, three pairs of salicylaldehyde derivative enantiomers, were isolated from a marine-derived fungus Eurotium sp. SCSIO F452. They exhibit highly constructed tetracyclic structures and show significant antioxidative activity and moderate cytotoxic activity.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Medicinal
Huaran Zhang, Yingying Chen, Yanqing Li, Yongxiang Song, Junying Ma, Jianhua Ju
Summary: The study on Streptomyces sp. SCSIO ZS0520 revealed new secondary metabolites and conducted bioinformatic analysis to lay foundations for solving remaining biosynthetic issues.
Article
Plant Sciences
Cunlei Cai, Yingying Chen, Le Zhou, Naying Gong, Hua Zhang, Changli Sun, Junying Ma, Jianhua Ju
Summary: Three diphenyl ethers (1-3) and a cyclopentenone (4), along with seven known compounds (5-11), were isolated from the fermentation broth of the marine sediment-derived fungus Spiromastix sp. SCSIO F190. Compound 3 and 4 exist as atropisomers and racemates, respectively. These compounds showed activities against various pathogenic bacteria, with compounds 1-4 exhibiting strong activity against Gram-positive bacteria, including methicillin-resistant strains.
JOURNAL OF NATURAL PRODUCTS
(2023)
Article
Chemistry, Medicinal
Yuxiu Ye, Jiaqi Liang, Jianglian She, Xiuping Lin, Junfeng Wang, Yonghong Liu, Dehua Yang, Yanhui Tan, Xiaowei Luo, Xuefeng Zhou
Summary: Marine sponge-derived fungi have been found to produce bioactive natural products, including two new alkaloids (polonimides E and D) and a new butenolide derivative (eutypoid F). In addition, thirteen known compounds were also isolated from the fungus Penicillium sp. SCSIO 41413. The inhibitory effects of the butenolide derivatives on the enzyme PI3K were investigated, and two compounds showed significant binding to the PI3K protein. Furthermore, two compounds exhibited inhibitory activity against LPS-induced NF-kappa B activation in cells.
Article
Chemistry, Medicinal
Cheng Fan, Guoliang Zhou, Wenxue Wang, Guojian Zhang, Tianjiao Zhu, Qian Che, Dehai Li
Summary: A new tetralone derivative, aladothalen, and a known biogenetically related compound were isolated from a deep-sea-derived-fungal Cladosporium sp. HDN17-58. Compound 1 showed strong bacteriostatic activity against various bacteria with a MIC value of 25 mu M.
NATURAL PRODUCT COMMUNICATIONS
(2021)
Article
Plant Sciences
Xia Cheng, Xiao Liang, Fei-Hua Yao, Xiao-Bo Liu, Shu-Hua Qi
Summary: In this study, 11 new fusidane-type nortriterpenoids were isolated from a marine-derived fungus, and their structures and absolute configurations were determined using various methods. One of the compounds showed strong antibacterial activity against Staphylococcus aureus.
JOURNAL OF NATURAL PRODUCTS
(2021)
Article
Microbiology
Xue Ren, Chunmei Chen, Yuxiu Ye, Ziying Xu, Qingliang Zhao, Xiaowei Luo, Yonghong Liu, Peng Guo
Summary: New chlorinated compounds were isolated from mangrove endophytic fungus, showing inhibitory effects on inflammation and lung injury.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Chemistry, Applied
Xin Qi, Wei-Hao Chen, Xiu-Ping Lin, Sheng-Rong Liao, Bin Yang, Xue-Feng Zhou, Yong-Hong Liu, Jun-Feng Wang, Yong Li
Summary: A new glyoxylate-containing benzene derivative (Compound 1) was isolated from the marine algicolous fungus, Aspergillus sp. SCSIO 41304, along with ten known compounds. Compound 1 possesses a rare methyl glyoxylate moiety and shows antibacterial and enzyme inhibitory activities. Among the tested compounds, aspulvinone H (Compound 4) showed moderate inhibition against acetylcholinesterase and pancreatic lipase.
NATURAL PRODUCT RESEARCH
(2023)
Article
Agricultural Engineering
Na Wang, Zishuo Chen, Jinting Lv, Tao Li, Hualian Wu, Jiayi Wu, Houbo Wu, Wenzhou Xiang
Summary: In this study, three new water-soluble polysaccharides fractions (RSP-1, RSP-2 and RSP-3) were isolated from Rhodosorus sp. SCSIO-45730. They had different chemical compositions and non-triple helical structures. RSP-1 contained 1,4-linked Galp, 1,3,6-linked Galp and t-Glcp, while RSP-2 and RSP-3 contained 1,4-linked Galp, 1,4,6-linked Galp and t-GalAp. The polysaccharides exhibited random coil configurations with α/8 glycosidic bonds and different morphology features. RSP-2 showed the strongest inhibitory activities on alpha-amylase and alpha-glucosidase, while RSP-1 and RSP-3 exhibited significant antioxidant effects.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Biochemistry & Molecular Biology
Ming-Min Xie, Jia-Yang Jiang, Zheng-Biao Zou, Lin Xu, Yong Zhang, Chao-Feng Wang, Cheng-Bin Liu, Qing-Xiang Yan, Zhu Liu, Xian-Wen Yang
Summary: Cladosporium fungi can produce various bioactive secondary metabolites, and ergosterol has a moderate inhibitory effect on Vibrio parahemolyticus.
CHEMISTRY & BIODIVERSITY
(2022)
Article
Chemistry, Medicinal
Pengyun Mou, Qingbo Zhang, Jing Peng, Xiaodong Jiang, Liping Zhang, Zhongbo Zhou, Changsheng Zhang, Yiguang Zhu
Summary: Five new phenylspirodrimanes were isolated from a marine-derived fungus, along with four known compounds. Their structures were determined through spectroscopic analyses, and two of the compounds exhibited moderate antibacterial activities against various bacteria.
Article
Chemistry, Medicinal
You-Jia Hao, Zheng-Biao Zou, Ming-Min Xie, Yong Zhang, Lin Xu, Hao-Yu Yu, Hua-Bin Ma, Xian-Wen Yang
Summary: Two new xanthones (1 and 2) were isolated from deep-sea-derived fungus Penicillium sp. MCCC 3A00126, along with 34 known compounds (3-36). The structures of the new compounds were determined using spectroscopic data. The absolute configuration of compound 1 was confirmed by comparing experimental and calculated ECD spectra. Cytotoxicity and ferroptosis inhibitory activities of all isolated compounds were evaluated. Compounds 14 and 15 showed potent cytotoxicity against CCRF-CEM cells, with IC50 values of 5.5 and 3.5 μM, respectively. Compounds 26, 28, 33, and 34 exhibited significant inhibitory effects on RSL3-induced ferroptosis, with EC50 values of 11.6, 7.2, 11.8, and 2.2 μM, respectively.
Article
Biochemistry & Molecular Biology
Gan Rao, Gaolong Zhong, Ting Hu, Shaofeng Wu, Jiajia Tan, Xiaoyong Zhang, Riming Huang, Zhaoxin Tang, Lianmei Hu
Summary: In this study, ducks were used to mimic arsenic trioxide (ATO) exposure and investigate its mechanism of cardiac toxicity. The results showed that ATO inhibited body and organ growth, increased LDH levels, and caused deformity and ischemia infarction in ducks. Transmission electron microscopy revealed that ATO exacerbated mitochondrial swelling and cell nuclei contraction in the duck heart. ATO also induced oxidative stress and apoptosis, via the Nrf 2/Caspase 3 signaling pathway, by altering the expression levels of various genes and proteins related to apoptosis and oxidative stress.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Correction
Biochemistry & Molecular Biology
Gan Rao, Gaolong Zhong, Ting Hu, Shaofeng Wu, Jiajia Tan, Xiaoyong Zhang, Riming Huang, Zhaoxin Tang, Lianmei Hu
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Microbiology
Keyue Wu, Yongchun Liu, Xinyu Liao, Xinyue Yang, Zihui Chen, Li Mo, Saiyi Zhong, Xiaoyong Zhang
Summary: This study investigated the fungal diversity and composition in the coastal environments of Guangdong using high-throughput sequencing and examined the correlation between fungal genera and environmental factors. A total of 2056 fungal operational taxonomic units (OTUs) belonging to 147 genera were identified, with Archaeorhizomyces and Aspergillus being the most dominant genera. Notably, 14 genera were identified as coastal fungi for the first time. The study also found significant correlations between nine fungal genera and environmental factors, indicating the importance of these factors in shaping fungal communities.
Article
Chemistry, Multidisciplinary
Maosheng Li, Hongyu Li, Xiaoyong Zhang, Xianhong Wang, Youhua Tao
Summary: Exploiting non-covalent interactions to catalyze ionic polymerizations is still in its early stages. A recent study demonstrated non-covalent anion-binding catalysis for living cationic polymerization of vinyl ethers. This study further investigates the structure-reactivity relationships and roles of anion-binding interactions in the catalytic process. The findings provide insights into the mechanism of anion-binding catalytic polymerization and offer guidance for future catalyst design.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Physical
Kuan Wang, Dan Wang, Xiao-Yong Zhang, Junlei Wang, Sheng-Li Lv, Zhen-Hong He, Huan Wang, Weitao Wang, Yang Yang, Zhao-Tie Liu
Summary: A series of modified N-doped Nb2O5 catalysts were prepared by using a modular calcination strategy combining hydrogen, vacuum, air, and ammonia modules. Among these modified catalysts, HN-Nb2O5 showed the best photocatalytic performance for the photo-oxidation of cyclohexane. The outstanding performance can be attributed to the abundant chemical defects of oxygen vacancies and Nb4+, as well as the presence of NOx species, which enhanced light absorption and effective electron-hole separation.
APPLIED SURFACE SCIENCE
(2023)
Article
Fisheries
Hong-yu Zhang, Ying Huang, Ning Ma, Hai-bo Wang, Xiao-yong Zhang, Ying-chun Xing, Lei Xia, Guang Yang, Li-lai Yuan, Ying-ren Li
Summary: This study evaluated the impact of trichloroisocyanuric acid (TCCA) on water quality index, heterotrophic bacteria, microbial community, and ecological function. The results showed that TCCA had a minimal effect on water quality but had a strong influence on heterotrophic bacteria, microbial community, and function.
Article
Chemistry, Physical
Jun Zhang, Zhen Tang, Xiaoyong Zhang, Hong Zhu, Ruoqi Zhao, Yangyi Lu, Jiali Gao
Summary: A flexible self-consistent field method called target state optimization (TSO) is introduced, which can explore electronic excited configurations and localized diabatic states. The TSO method partitions molecular orbitals into different subspaces based on the excitation or localization pattern of a target state, allowing for variationally optimized excited or diabatic configurations without collapsing back to the ground state. TSO-DFT has been shown to outperform conventional TD-DFT calculations for core excitation, doubly excited states, and charge-transfer states.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION
(2023)
Article
Plant Sciences
Guo-Xia Guo, Ke-Yue Wu, Xiao-Yong Zhang, Fu-Xiang Lai, Karl Wah-Keung Tsim, Qi-Wei Qin, Wei-Hui Hu
Summary: This study investigated the effects of Curcumae Longae Rhizoma (CLR) extract on angiogenesis and found that it significantly suppressed angiogenic responses such as proliferation, migration, invasion, and tube formation of endothelial cells. It also reduced subintestinal vessel formation in a zebrafish embryo model. Mechanistically, CLR extract inhibited the VEGF-triggered signaling pathway, decreased phosphorylated VEGFR2 levels, and inhibited downstream regulators. It also reduced the production of NO and ROS. Additionally, CLR extract suppressed cell migration and NF-Kappa B translocation in cancer cells.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Construction & Building Technology
Anchi Shi, Mowen Xie, Liuyuan Zhao, Xiaoyong Zhang, Zhixiang Wu, Simiao Wu
Summary: This paper proposes a method to identify the dynamic characteristics of a dangerous rock mass based on constant micromotion. By analyzing the dynamic parameters and characteristics of the rock mass, it is possible to determine the degree of surface damage. Integration of vibration mechanics theory and elastic wave scattering theory is found to be more effective in analyzing the damage of the structure of the rock mass.
ADVANCES IN CIVIL ENGINEERING
(2023)
Article
Construction & Building Technology
Xiaoyong Zhang, Mowen Xie, Zhengjun Huang, Yan Du, Lei Zhang, Zhixiang Wu, Zhuang Fan
Summary: In mountainous areas, the instability of dangerous rock mass poses a threat to human life and property safety. This study analyzed the dynamic characteristics of dangerous rock mass under constant micromotion, proposing that the center frequency of high-frequency components of elastic waves can reflect the damage degree of the dangerous rock mass. The research provides a new idea for the prevention and control of dangerous rock masses.
ADVANCES IN CIVIL ENGINEERING
(2023)
Article
Materials Science, Multidisciplinary
Shixia Cheng, Rensa Lv, Fei Cheng, Bin Han, Anqing Fu, Xiaoyong Zhang, Jianxun Zhang, Yaorong Feng, Huilin Gao
Summary: This paper introduces a kind of X100 pipeline steel with a multiphase structure of bainite and fine M/A constituent, which has high strength, toughness, and excellent plasticity. The Heating on-line partitioning (HOP) process is used to achieve the multiphase structure by diffusing carbon atoms from bainite to austenite, improving austenite stability and increasing the volume fraction of retained austenite. The widening of bainite laths and the decrease in dislocation density increase the plasticity, while carbides precipitation and martensite formation provide the steel with high strength.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Microbiology
Xinyu Liao, Jiadenghui Yang, Zanhu Zhou, Jinying Wu, Dunming Xu, Qiaoting Yang, Saiyi Zhong, Xiaoyong Zhang
Summary: This study investigated the intestinal fungal diversity of three coral reef fish and found that fungal communities in the intestines are influenced by their surrounding environments. The distribution of fungi in fish intestines may be related to the physiological functions of different intestinal segments. Some fungal isolates showed antimicrobial activity against marine pathogenic microorganisms.
Article
Chemistry, Multidisciplinary
Christian P. Hettich, Xiaoyong Zhang, David Kemper, Ruoqi Zhao, Shaoyuan Zhou, Yangyi Lu, Jiali Gao, Jun Zhang, Meiyi Liu
Summary: A multistate energy decomposition analysis (MS-EDA) method is introduced to analyze the energy components in molecular complexes in excited states. It partitions the total binding energy of an excimer or an exciplex into a ground-state term and excited-state contributions, providing quantitative insights into physical concepts such as exciton delocalization and superexchange charge-transfer effects. Based on the analysis, molecular complexes in excited states can be categorized into encounter excited-state complex, charge-transfer exciplex, and intimate excimer or exciplex. MS-EDA can serve as a useful tool for understanding photochemical and photobiological processes.
Article
Chemistry, Applied
Yongchun Liu, Wei Li, Keyue Wu, Bingfu Lei, Jianying Chen, Xiaoyong Zhang, Hongtao Lei, Xuewu Duan, Riming Huang
Summary: Developing high-efficiency and low-toxicity natural antifungal agents for green mold caused by Penicillium digitatum is urgent. MNQ-derived carbon dots (MNQ-CDs) were synthesized and used as antifungal agents against P. digitatum. MNQ-CDs showed enhanced antifungal activity compared to MNQ, with a minimum inhibitory concentration of 2.8 μg/mL. Omics data revealed that MNQ-CDs primarily modified the metabolism of aromatic amino acids and the synthesis of the cell membrane in P. digitatum, thereby inhibiting its propagation.
Article
Chemistry, Physical
Xiaoyong Zhang, Xuefeng Guo, Dan Liu
Summary: This computational study investigated the effect of solvent on the catalytic efficiency of CB7 in the dimerization of CPD. The results showed that water changes the alignment of CPD with CB7 during the reaction. The study emphasized the importance of host-guest interactions in the transition state for achieving excellent catalysis.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
