High Dietary Fat Intake Affects DNA Methylation/Hydroxymethylation in Mouse Heart: Epigenetic Hints for Obesity‐Related Cardiac Dysfunction

Epigenomes in Cardiovascular Disease

(2018) Manuel Rosa-Garrido et al.   CIRCULATION RESEARCH

Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats

(2018) Justus Stenzig et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Obesity and Cardiac Remodeling in Adults: Mechanisms and Clinical Implications

(2018) Martin A. Alpert et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Hints on ATGL implications in cancer: beyond bioenergetic clues

(2018) Rolando Vegliante et al.   Cell Death & Disease

Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo

(2018) Ralf Gilsbach et al.   Nature Communications

Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine

(2017) Arne Klungland et al.   FREE RADICAL BIOLOGY AND MEDICINE

DNA Hydroxymethylation Levels Are Altered in Blood Cells From Down Syndrome Persons Enrolled in the MARK-AGE Project

(2017) Fabio Ciccarone et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

TET-mediated active DNA demethylation: mechanism, function and beyond

(2017) Xiaoji Wu et al.   NATURE REVIEWS GENETICS

The TCA cycle as a bridge between oncometabolism and DNA transactions in cancer

(2017) Fabio Ciccarone et al.   SEMINARS IN CANCER BIOLOGY

Metabolic stress-induced cardiomyopathy is caused by mitochondrial dysfunction due to attenuated Erk5 signaling

(2017) Wei Liu et al.   Nature Communications

NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture

(2017) Maria B. Olsen et al.   Cell Reports

Effect of diabetes status and hyperglycemia on global DNA methylation and hydroxymethylation

(2017) Jairo Arturo Pinzón-Cortés et al.   Endocrine Connections

Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells From Type2 Diabetes Patients

(2017) Francesco Spallotta et al.   CIRCULATION RESEARCH

Prolonged high-fat diet induces gradual and fat depot-specific DNA methylation changes in adult mice

(2017) Ramona A. J. Zwamborn et al.   Scientific Reports

Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study

(2016) Elisabetta Valentini et al.   Aging-US

Obesity, Diabetes, and Cardiovascular Diseases

(2016) Philipp E. Scherer et al.   CIRCULATION RESEARCH

Targeted Expression of Catalase to Mitochondria Protects Against Ischemic Myopathy in High-Fat Diet–Fed Mice

(2016) Terence E. Ryan et al.   DIABETES

Vitamin C enhances substantially formation of 5-hydroxymethyluracil in cellular DNA

(2016) Martyna Modrzejewska et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of TET enzymes in DNA methylation, development, and cancer

(2016) Kasper Dindler Rasmussen et al.   GENES & DEVELOPMENT

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

(2016) Bernard Thienpont et al.   NATURE

5'-Hydroxymethylcytosine Precedes Loss of CpG Methylation in Enhancers and Genes Undergoing Activation in Cardiomyocyte Maturation

(2016) David K. Kranzhöfer et al.   PLoS One

DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy

(2016) Carolina M. Greco et al.   Nature Communications

Mitochondrial Hormesis links nutrient restriction to improved metabolism in fat cell

(2015) Daniele Lettieri Barbato et al.   Aging-US

cAMP induces hypertrophy and alters DNA methylation in HL-1 cardiomyocytes

(2015) Xiefan Fang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex

(2015) Lanfeng Wang et al.   NATURE

5-Formylcytosine can be a stable DNA modification in mammals

(2015) Martin Bachman et al.   Nature Chemical Biology

D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2

(2015) An-Ping Lin et al.   Nature Communications

The Interaction between Epigenetics, Nutrition and the Development of Cancer

(2015) Karen Bishop et al.   Nutrients

Hearts from Mice Fed a Non-Obesogenic High-Fat Diet Exhibit Changes in Their Oxidative State, Calcium and Mitochondria in Parallel with Increased Susceptibility to Reperfusion Injury

(2014) Ben Littlejohns et al.   PLoS One

PGC-1α buffers ROS-mediated removal of mitochondria during myogenesis

(2014) S Baldelli et al.   Cell Death & Disease

Inhibition of DNA methylation reverses norepinephrine-induced cardiac hypertrophy in rats

(2013) DaLiao Xiao et al.   CARDIOVASCULAR RESEARCH

Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming

(2013) Chun-Xiao Song et al.   CELL

Left-ventricular hypertrophy and obesity

(2013) Cesare Cuspidi et al.   JOURNAL OF HYPERTENSION

A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation

(2013) Mario Iurlaro et al.   GENOME BIOLOGY

Mitochondrial Fatty Acid Oxidation in Obesity

(2012) Dolors Serra et al.   ANTIOXIDANTS & REDOX SIGNALING

Developmental expression and cardiac transcriptional regulation of Myh7b, a third myosin heavy chain in the vertebrate heart

(2012) Andrew S. Warkman et al.   Cytoskeleton

Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase

(2012) Eun-Ang Raiber et al.   GENOME BIOLOGY

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

(2011) C. E. Nestor et al.   GENOME RESEARCH

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

Cardiac electrical remodeling in health and disease

(2011) Michael J. Cutler et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The phosphate makes a difference: cellular functions of NADP

(2010) Line Agledal et al.   REDOX REPORT