Heat-shock protein 90α is involved in maintaining the stability of VP16 and VP16-mediated transactivation of α genes from herpes simplex virus-1

Could targeting the heat shock protein 90 revolutionize antiviral therapy?

(2018) Yiliang Wang et al.   Future Virology

Herpes simplex virus 1 infection dampens the immediate early antiviral innate immunity signaling from peroxisomes by tegument protein VP16

(2017) Chunfu Zheng et al.   Virology Journal

NEAT1 modulates herpes simplex virus-1 replication by regulating viral gene transcription

(2016) Ziqiang Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autophagy is involved in regulating influenza A virus RNA and protein synthesis associated with both modulation of Hsp90 induction and mTOR/p70S6K signaling pathway

(2016) Ge Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells

(2016) WEI HE et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

HSP90 regulates temperature-dependent seedling growth in Arabidopsis by stabilizing the auxin co-receptor F-box protein TIR1

(2016) Renhou Wang et al.   Nature Communications

Inhibition of HSV-1 Replication by Gene Editing Strategy

(2016) Pamela C. Roehm et al.   Scientific Reports

Hsp90, the Concertmaster: Tuning Transcription

(2015) Nidhi Khurana et al.   Frontiers in Oncology

Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells

(2014) MASAKI MORI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Heat-Shock Protein 90 Promotes Nuclear Transport of Herpes Simplex Virus 1 Capsid Protein by Interacting with Acetylated Tubulin

(2014) Meigong Zhong et al.   PLoS One

Epidermal Growth Factor Receptor-PI3K Signaling Controls Cofilin Activity To Facilitate Herpes Simplex Virus 1 Entry into Neuronal Cells

(2014) K. Zheng et al.   mBio

Herpes Simplex Virus 1-Encoded Tegument Protein VP16 Abrogates the Production of Beta Interferon (IFN) by Inhibiting NF- B Activation and Blocking IFN Regulatory Factor 3 To Recruit Its Coactivator CBP

(2013) J. Xing et al.   JOURNAL OF VIROLOGY

HSP90 Protects the Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax Oncoprotein from Proteasomal Degradation To Support NF- B Activation and HTLV-1 Replication

(2013) L. Gao et al.   JOURNAL OF VIROLOGY

Heat shock protein-90-beta facilitates enterovirus 71 viral particles assembly

(2013) Robert Y.L. Wang et al.   VIROLOGY

Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors

(2012) Yang-Fei Xiang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cofilin 1-Mediated Biphasic F-Actin Dynamics of Neuronal Cells Affect Herpes Simplex Virus 1 Infection and Replication

(2012) Yangfei Xiang et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus 1 ICP22 Inhibits the Transcription of Viral Gene Promoters by Binding to and Blocking the Recruitment of P-TEFb

(2012) Lei Guo et al.   PLoS One

Autophagy Inhibitor Chloroquine Enhanced the Cell Death Inducing Effect of the Flavonoid Luteolin in Metastatic Squamous Cell Carcinoma Cells

(2012) Lien Verschooten et al.   PLoS One

West Nile virus growth is independent of autophagy activation

(2012) Erica Beatman et al.   VIROLOGY

Roles of the Nuclear Lamina in Stable Nuclear Association and Assembly of a Herpesviral Transactivator Complex on Viral Immediate-Early Genes

(2012) L. Silva et al.   mBio

Hsp90 Inhibitors Are Efficacious against Kaposi Sarcoma by Enhancing the Degradation of the Essential Viral Gene LANA, of the Viral Co-Receptor EphA2 as well as Other Client Proteins

(2012) Wuguo Chen et al.   PLoS Pathogens

Quality control and fate determination of Hsp90 client proteins

(2011) Maria A. Theodoraki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Synthesis and in vitro anti-HSV-1 activity of a novel Hsp90 inhibitor BJ-B11

(2011) Huai-Qiang Ju et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

SNX-2112, an Hsp90 inhibitor, induces apoptosis and autophagy via degradation of Hsp90 client proteins in human melanoma A-375 cells

(2011) Kai-Sheng Liu et al.   CANCER LETTERS

Proteomic analyses of the SMYD family interactomes identify HSP90 as a novel target for SMYD2

(2011) Mohamed Abu-Farha et al.   Journal of Molecular Cell Biology

Pentagalloylglucose downregulates cofilin1 and inhibits HSV-1 infection

(2010) Ying Pei et al.   ANTIVIRAL RESEARCH

Integration of Clearance Mechanisms: The Proteasome and Autophagy

(2010) E. Wong et al.   Cold Spring Harbor Perspectives in Biology

The herpes simplex virus type 1 infected cell protein 22

(2010) Fu-sen Lin et al.   VIROLOGICA SINICA

The nuclear signaling of NF-κB: current knowledge, new insights and future perspectives

(2009) Fengyi Wan et al.   CELL RESEARCH

Transcriptomic and proteomic approach to studying SNX-2112-induced K562 cells apoptosis and anti-leukemia activity in K562-NOD/SCID mice

(2009) Lin Jin et al.   FEBS LETTERS

Inhibition of the histone demethylase LSD1 blocks α-herpesvirus lytic replication and reactivation from latency

(2009) Yu Liang et al.   NATURE MEDICINE

HSP90/70 chaperones are required for rapid nucleosome removal upon induction of the GAL genes of yeast

(2008) M. Floer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA