Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity

Title
Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity
Authors
Keywords
cryo-EM, type III-A CRISPR-Cas complexes, T. onnurineus, Csm, ternary complex assembly with crRNA and target RNA, 5′ repeat tag pairing controls autoimmunity, RNA cleavage with 6-nt periodicity, DNase activity regulation by Glu residues
Journal
MOLECULAR CELL
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2018-11-30
DOI
10.1016/j.molcel.2018.11.007

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